Results 81 to 90 of about 3,274,672 (298)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Interpretation and acceptance of the term 'cancer survivor': A United Kingdom-based qualitative study

open access: yes, 2011
The concept of cancer survivorship and the term 'cancer survivor' remains widely interpreted. The aim is to explore the interpretations of the term 'cancer survivor' amongst British people living past a cancer diagnosis.
S. HARRISON   +4 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Understanding the delays in diagnosis of breast cancer in India using blogs and YouTube videos

open access: yesBMC Public Health
Background Globally, breast cancer is the most common cancer among women and is the second leading cause of cancer-related deaths. Breast cancer-related mortality has surged among Indian women, as a significant number of women present at an advanced ...
Nishita Sarah Thomas, Emma Norris
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Psychological Distress among Breast Cancer Survivor and Their Spousal Caregiver

open access: yesJournal of Nepal Health Research Council
Background: Cancer journey increases the risk for anxiety and depression not only for the breast cancer survivor but also for the spousal caregiver. The purpose of this study was to determine the relationship between psychological distress among breast ...
Abha Sharma   +3 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Survivor centrality among breast cancer survivors: implications for well-being.

open access: yes, 2018
OBJECTIVE: The goal of this research was to examine the extent to which 10-year breast cancer survivors integrated cancer into their self-concept (i.e.
Vicki Helgeson (3895396)
core   +1 more source

Role of Cardiovascular Health in the Bidirectional Progression Trajectories Between Cardiovascular Disease, Type 2 Diabetes, and Cancer

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background There existed bidirectional associations of cardiovascular disease (CVD) and type 2 diabetes (T2D) with cancer, partly attributed to their shared risk factors.
Yu Peng   +7 more
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

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