From single cell analysis to 3D micro physiological systems: microfluidic tools integrating cancer cell targets for delineating natural killer cell biology. [PDF]
Hangad MV, Ma H, Kung SKP, Lin F.
europepmc +1 more source
Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson +2 more
wiley +1 more source
Harnessing human tumor organoids for cancer modeling and precision therapy. [PDF]
Zhou T, Wang Q, Zhang M, Huang Y.
europepmc +1 more source
Correction: Holtkamp et al. Ultraviolet Radiation-Induced Mitochondrial Disturbances Are Attenuated by Metabolites of Melatonin in Human Epidermal Keratinocytes. <i>Metabolites</i> 2023, <i>13</i>, 861. [PDF]
Holtkamp CE +10 more
europepmc +1 more source
Strategic decoupling between grant and publication language in AI and cancer research: a cross-national LLM-assisted analysis. [PDF]
Wang X, Sun Y.
europepmc +1 more source
Engineered Bacterial Membranes as Next-Generation Platforms for Cancer Immunotherapy. [PDF]
Malik HA +4 more
europepmc +1 more source
Special Issue "<i>Drosophila</i>: A Versatile Model in Biology and Medicine-2nd Edition". [PDF]
Giansanti MG, Piergentili R.
europepmc +1 more source
Stress-specific 14-3-3-client modules in digestive cancers: an evidence-graded review of adaptive survival and therapy resistance. [PDF]
Li R, Zhao Z, Wang X.
europepmc +1 more source
Systems biology of cancer biomarker detection
Cancer systems-biology is an ever-growing area of research due to explosion of data; how to mine these data and extract useful information is the problem. To have an insight on carcinogenesis one need to systematically mine several resources, such as databases, microarray and next-generation sequences. This review encompasses management and analysis of
Sanga, Mitra +2 more
openaire +3 more sources
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Cancer is a complex and heterogeneous disease, not only at a genetic and biochemical level, but also at a tissue, organism, and population level. Multiple data streams, from reductionist biochemistry in vitro to high-throughput "-omics" from clinical material, have been generated with the hope that they encode useful information about phenotype and ...
Dana, Faratian +4 more
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