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Systems Biology Approaches in Cancer Pathology
2018The complex network of the tissue system, in both pre-neoplastic tissues and tumors, demonstrates the need for a systems biology approach to cancer pathology, in which quantification of key tissue system processes is combined with informatics tools to produce actionable scores to aid clinical decision-making.
Aaron, DeWard +1 more
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Systems Biology Applied to Cancer Research
2009Complex diseases such as cancer have multiple origins and are therefore difficult to understand and cure. Highly parallel technologies such as DNA microarrays are now available. These provide a data deluge which needs to be mined for relevant information and integrated to existing knowledge at different scales.
Seigneuric, Renaud +6 more
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Abstract In contrast to prevailing wisdom that cancer is a genetic disease that evolves via Darwinian selection, it is increasingly recognized that in addition to genetic mutations, intratumoral heterogeneity also results through non-genetic mechanisms.
Ravi Salgia +3 more
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Ravi Salgia +3 more
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Blueprint for cancer research: Critical gaps and opportunities
Ca-A Cancer Journal for Clinicians, 2021exaly
Inflammatory Breast Cancer: The Disease, the Biology, the Treatment
Ca-A Cancer Journal for Clinicians, 2010Luc Bidaut, Thomas Buchholz
exaly