Results 221 to 230 of about 1,632,468 (362)

Microengineered Biomaterials and Biosystems for Systems Immunology, Cancer Biology, and Stem Cell-based Regenerative Medicine

, 2014
Weiqiang Chen
openalex   +1 more source

Exploiting systems biology to investigate the gene modules and drugs in ovarian cancer: A hypothesis based on the weighted gene co-expression network analysis

, 2021
Samira Nomiri, Hassan Karami, Behzad Baradaran, Darya Javadrashid, Afshin Derakhshani, Niloufar Sadat Nourbakhsh, Mahdi Abdoli Shadbad, Antonio Giovanni Solimando, Neda Jalili Tabrizi, Oronzo Brunetti, Saeed Nasseri, Vito Racanelli, Hossein Safarpour, Nicola Silvestris   +13 more
openalex   +1 more source

A unified model for Duchenne muscular dystrophy gene involvement in cancer: context‐dependent tumour suppression and oncogenicity

FEBS Open Bio, EarlyView.
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado, Leanne Jones, Sonika Divakar, Michael Naidoo, Karen Anthony   +4 more
wiley   +1 more source

Editorial: Bioinformatics and systems biology strategies in disease management with a special emphasis on cancer, Alzheimer's disease and aging. [PDF]

Front Mol Biosci
Singh TR, Vannier B, Singh RR, Yadav HO, Fröhlich H.   +4 more
europepmc   +1 more source

Systems biology strategy for drug potentiating through drug repurposing:bisphosphonates beyond osteoporosis treatment [PDF]

, 2018
Goltsov, Alexey, Kowalczyk, Zuzanna, Papineni, Rao V. L.   +2 more
core   +2 more sources

Systems biology based elucidation and experimental validation of anticancer effects of warfarin in vulvar cancer [PDF]

Jianwei Liang, Qiang Yao, Xingtao Pi, Yuan Liu, Wendong Cao, Shanchen Wei, Wendong Feng   +6 more
openalex   +1 more source

Electrical pulse stimulation reflecting the episodic nature of real‐life exercise modulates metabolic and secretory profile of primary human myotubes

FEBS Open Bio, EarlyView.
Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová, Tímea Kurdiová, Daria Barkova, Natália Pálešová, Jana Babulicová, Silvia Tyčiaková, Marta Novotová, Mária Balážová, Miroslav Sabo, Václav Pustka, Jozef Ukropec, Barbara Ukropcová   +11 more
wiley   +1 more source

Supplementary Figure S8 from A Systems Biology Approach to Understand the Racial Disparities in Colorectal Cancer

Annabelle Nwaokorie, Walter Kölch, Dirk Fey   +2 more
openalex   +1 more source

Structural systems biology: from bacterial to cancer networks [PDF]

, 2014
Adam Godzik
openalex   +1 more source

Establishment and optimization of the two‐step induction system for generating primordial germ cell‐like cells from chicken embryonic stem cells

FEBS Open Bio, EarlyView.
This study optimizes a two‐step induction system to generate PGCLCs from chicken ESCs. The induced cells express germline markers and migrate to gonads in ovo, offering a novel approach for avian genetic resource conservation. Primordial germ cells (PGCs) are the progenitor cells of sperm and eggs.
Zeyu Li, XianShuai Xu, GuangZheng Liu, XiaoQian Lv, JiuZhou Song, HongYan Sun, YingJie Niu, QiSheng Zuo, Wei Han, BiChun Li, Kai Jin   +10 more
wiley   +1 more source