Results 321 to 330 of about 1,632,468 (362)
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Bioinformatics and Systems Biology of Cancers
2010Molecular databases and bioinformatics methods and tools are essential for modern cancer research. Multilevel analyses of all the protein-coding genes, thousands of proteins, and hundreds of metabolites require integration in terms of signaling and metabolic pathways and networks.
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Systems Biology of MicroRNAs in Cancer
2022This book provides an update on the latest development in the field of microRNAs in cancer research with an emphasis on translational research. Since the early 2000s, microRNAs have been recognized as important and ubiquitous regulators of gene expression. Soon it became evident that their deregulation can cause human diseases including cancer.
Schmitz, Ulf +2 more
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Introduction: Cancer Systems and Integrative Biology
2023The insights provided by the holistic approaches of systems and integrative biology offer a means to address the multiple levels of complexity evident in cancer biology. Often focused on the use of large-scale, high-dimensional omics data for discovery in silico, integration with lower-dimensional data and lower-throughput wet laboratory studies allows
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The chemokine system in cancer biology and therapy
Cytokine & Growth Factor Reviews, 2010Chemokines are a key component of cancer-related inflammation. Chemokines and chemokine receptors are downstream of genetic events that cause neoplastic transformation and are components of chronic inflammatory conditions, which predispose to cancer. Components of the chemokine system affect in a cell autonomous or non-autonomous way multiple pathways ...
A. Mantovani +5 more
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Medecine sciences : M/S, 2010
Cancer Systems Biology is now accepted and recognized as a promising field both in biological and clinical research. It relies on a rigorous formalization of regulation networks into precise and unambiguous languages. It provides both detailed and modular views of the complex biological system of interest (which in cancer research is typically an ...
Emmanuel, Barillot +2 more
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Cancer Systems Biology is now accepted and recognized as a promising field both in biological and clinical research. It relies on a rigorous formalization of regulation networks into precise and unambiguous languages. It provides both detailed and modular views of the complex biological system of interest (which in cancer research is typically an ...
Emmanuel, Barillot +2 more
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Systems biology of cancer biomarker detection
Cancer Biomarkers, 2013Cancer systems-biology is an ever-growing area of research due to explosion of data; how to mine these data and extract useful information is the problem. To have an insight on carcinogenesis one need to systematically mine several resources, such as databases, microarray and next-generation sequences. This review encompasses management and analysis of
Sanga, Mitra +2 more
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Systems Biology Applied to Cancer Research
2009Complex diseases such as cancer have multiple origins and are therefore difficult to understand and cure. Highly parallel technologies such as DNA microarrays are now available. These provide a data deluge which needs to be mined for relevant information and integrated to existing knowledge at different scales.
Seigneuric, Renaud +6 more
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2010
Foreword Hiroaki Kitano, President, The Systems Biology Institute, Tokyo, Japan CANCER SYSTEMS BIOLOGY: CONCEPTS AND APPLICATIONS A Roadmap of Cancer Systems Biology Edwin Wang Network Biology, the Framework of Systems Biology Jing-Dong Han Reconstructing Gene Networks Using Gene Expression Profiles Mario Lauria and Diego di Bernardo Understanding ...
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Foreword Hiroaki Kitano, President, The Systems Biology Institute, Tokyo, Japan CANCER SYSTEMS BIOLOGY: CONCEPTS AND APPLICATIONS A Roadmap of Cancer Systems Biology Edwin Wang Network Biology, the Framework of Systems Biology Jing-Dong Han Reconstructing Gene Networks Using Gene Expression Profiles Mario Lauria and Diego di Bernardo Understanding ...
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