Results 271 to 280 of about 1,972,453 (318)
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Glycosaminoglycans in cancer therapy
American Journal of Physiology-Cell Physiology, 2022Glycosaminoglycans (GAGs) are an important component of the tumor microenvironment (TME). GAGs can interact with a variety of binding partners and thereby influence cancer progression on multiple levels. GAGs can modulate growth factors and chemokine signaling, invasion, and metastasis formation. Moreover, GAGs are able to change the physical property
Ronja Wieboldt, Heinz Läubli
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Surgical Oncology Clinics of North America, 1998
Developments in molecular genetics, immunology, molecular and cellular biology, and tumor biology have given rise to the field of cancer gene therapy. Several gene delivery vehicles have been developed and are being examined in clinical trials. Most cancer gene therapy strategies involve introduction of genes to augment existing therapies.
J C, Cusack, K K, Tanabe
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Developments in molecular genetics, immunology, molecular and cellular biology, and tumor biology have given rise to the field of cancer gene therapy. Several gene delivery vehicles have been developed and are being examined in clinical trials. Most cancer gene therapy strategies involve introduction of genes to augment existing therapies.
J C, Cusack, K K, Tanabe
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Apoptosis, cancer and cancer therapy
Surgical Oncology, 1997Apoptosis is a specific process that leads to programmed cell death through the activation of an evolutionary conserved intracellular pathway leading to pathognomic cellular changes distinct from cellular necrosis. Apoptosis is essential in the homeostasis of normal tissues of the body, especially those of the gastrointestinal tract, immune system and ...
R J, Bold, P M, Termuhlen, D J, McConkey
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2023
Abstract Heart failure can be caused by a range of cardiotoxic cancer therapies. The most common are anthracycline chemotherapy and human epidermal growth factor receptor 2 (HER2)-targeted therapies. However, with the development of targeted molecular cancer therapies, the number of cancer treatments causing heart failure are increasing ...
Dimitrios Farmakis +3 more
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Abstract Heart failure can be caused by a range of cardiotoxic cancer therapies. The most common are anthracycline chemotherapy and human epidermal growth factor receptor 2 (HER2)-targeted therapies. However, with the development of targeted molecular cancer therapies, the number of cancer treatments causing heart failure are increasing ...
Dimitrios Farmakis +3 more
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MEK in cancer and cancer therapy
Pharmacology & Therapeutics, 2014The mitogen-activated extracellular signal-regulated kinase (MEK) pathway is one of the best-characterized kinase cascades in cancer cell biology. It is triggered by either growth factors or activating mutations of major oncogenic proteins in this pathway, the most common being Ras and Raf.
Cindy, Neuzillet +5 more
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The microbiome, cancer, and cancer therapy
Nature Medicine, 2019With the advent of next-generation sequencing, we have an unprecedented ability to study tumor and host genomes as well as those of the vast array of microorganisms that exist within living organisms. Evidence now suggests that these microbes may confer susceptibility to certain cancers and may also influence response to therapeutics.
Beth A, Helmink +4 more
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Cancer Letters, 2007
Several groups have reported in recent years that members of the plant stress hormones family of jasmonates, and some of their synthetic derivatives, exhibit anti-cancer activity in vitro and in vivo. Jasmonates increased the life span of EL-4 lymphoma-bearing mice, and exhibited selective cytotoxicity towards cancer cells while sparing normal blood ...
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Several groups have reported in recent years that members of the plant stress hormones family of jasmonates, and some of their synthetic derivatives, exhibit anti-cancer activity in vitro and in vivo. Jasmonates increased the life span of EL-4 lymphoma-bearing mice, and exhibited selective cytotoxicity towards cancer cells while sparing normal blood ...
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Cancer Nursing, 1994
Advances in molecular biology and technology now being made will open the way to using gene transfer as a therapeutic option for patients with cancer. Since there are > 5,000 known genetic diseases, the potential impact of these techniques is enormous.
J, Jenkins, V, Wheeler, L, Albright
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Advances in molecular biology and technology now being made will open the way to using gene transfer as a therapeutic option for patients with cancer. Since there are > 5,000 known genetic diseases, the potential impact of these techniques is enormous.
J, Jenkins, V, Wheeler, L, Albright
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Radiology, 1952
In the last few years we have all witnessed with varying degrees of interest a tremendous increase in the upper limits of supravoltage energies for possible therapeutic application. A variety of radiations have become available, some in adequate quantity for the first time. We have been using a 24,000,000-volt betatron which yields a very powerful beam
R A, HARVEY, L L, HAAS, J S, LAUGHLIN
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In the last few years we have all witnessed with varying degrees of interest a tremendous increase in the upper limits of supravoltage energies for possible therapeutic application. A variety of radiations have become available, some in adequate quantity for the first time. We have been using a 24,000,000-volt betatron which yields a very powerful beam
R A, HARVEY, L L, HAAS, J S, LAUGHLIN
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BioDrugs, 2010
Recent advances in understanding the biologic mechanisms underlying cancer development have driven the design of new therapeutic approaches, termed 'targeted therapies', that selectively interfere with molecules or pathways involved in tumor growth and progression.
Ciavarella S +3 more
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Recent advances in understanding the biologic mechanisms underlying cancer development have driven the design of new therapeutic approaches, termed 'targeted therapies', that selectively interfere with molecules or pathways involved in tumor growth and progression.
Ciavarella S +3 more
openaire +3 more sources