Results 291 to 300 of about 15,755,427 (366)

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

Arginine Methylation in Alternative Splicing: Implications for Cancer Therapy. [PDF]

J Cell Physiol
Li Y, Chen S, Ding W, Pan B, Yin Y, Xin X, Xia D, Wei X, Bao S, Xu M.   +9 more
europepmc   +1 more source

Autophagy Modulation in Cancer Therapy: Navigating the Dual Roles to Overcome Chemoresistance. [PDF]

Health Sci Rep
Mohiuddin M, Ahsan MAM.
europepmc   +1 more source

Antitumor properties of fungal-derived compounds: potential applications in skin cancer therapy. [PDF]

Mol Biol Rep
Kloc M, Jonderko L, Herbetko K, Kublińska K, Wojno A, Cichy O, Wojno A, Karwowska A, Suwała S, Choromańska A.   +9 more
europepmc   +1 more source

Preclinical characterization of a reversible XPO1 inhibitor for cancer therapy. [PDF]

Nat Commun
Van Hauwenhuyse J, Reniers F, Persoons L, Noppen S, Wing CE, Niesman AB, Fung HYJ, Vanstreels E, Jacquemyn M, Boel E, Vankerckhoven A, Berckmans Y, Kwanten B, Coosemans A, Van den Mooter G, Chook YM, Dehaen W, Daelemans D.   +17 more
europepmc   +1 more source

Protein-Based Nanomaterials for Cancer Therapy: A Comparative and Translational Perspective. [PDF]

Pharmaceutics
Gonzalez-Valdivieso J, Gutiérrez J, Vásquez Calero JA, Escalera-Anzola S, Muñoz R, Arias FJ, Rojo MÁ, Girotti A.   +7 more
europepmc   +1 more source

Adipocytes as Orchestrators of Multimodal Cancer Therapy Resistance. [PDF]

Biomol Ther (Seoul)
Park J, Cho J.
europepmc   +1 more source

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Endocytosis in cancer and cancer therapy

Nature Reviews Cancer, 2023
Endocytosis is a complex process whereby cell surface proteins, lipids and fluid from the extracellular environment are packaged, sorted and internalized into cells. Endocytosis is also a mechanism of drug internalization into cells. There are multiple routes of endocytosis that determine the fate of molecules, from degradation in the lysosomes to ...
B. Banushi, Shannon R. Joseph, Benedict Lum, Jason J. Lee, F. Simpson   +4 more
semanticscholar   +5 more sources

Nanocarriers as an Emerging Platform for Cancer Therapy

Nano-Enabled Medical Applications, 2020
Nanotechnology has the potential to revolutionize cancer diagnosis and therapy. Advances in protein engineering and materials science have contributed to novel nanoscale targeting approaches that may bring new hope to cancer patients. Several therapeutic
D. Peer, J. Karp, Seungpyo Hong, O. Farokhzad, R. Margalit, R. Langer   +5 more
semanticscholar   +1 more source