Results 61 to 70 of about 5,708,022 (299)

Targeting purinergic pathway to enhance radiotherapy-induced immunogenic cancer cell death

Journal of Experimental & Clinical Cancer Research, 2022
Emerging evidence has demonstrated that radiotherapy (RT) can not only cause direct damage to cancer cells but also lead to immunogenic cell death (ICD), which involves the activation of host antitumor immune response in tumor immune microenvironment ...
Xuhui Bao, Liyi Xie
doaj   +1 more source

Virus-like Particles as Preventive and Therapeutic Cancer Vaccines

Vaccines, 2022
Virus-like particles (VLPs) are self-assembled viral protein complexes that mimic the native virus structure without being infectious. VLPs, similarly to wild type viruses, are able to efficiently target and activate dendritic cells (DCs) triggering the ...
A. Tornesello, M. Tagliamonte, F. Buonaguro, M. Tornesello, L. Buonaguro   +4 more
semanticscholar   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Detecting horizontal gene transfer with metagenomics co-barcoding sequencing

Microbiology Spectrum
Horizontal gene transfer (HGT) is the process through which genetic information is transferred between different genomes and that played a crucial role in bacterial evolution.
Kai Han, Jiarui Li, Duo Yang, Qinghui Zhuang, Hui Zeng, Chengbo Rong, Jinglin Yue, Na Li, Chaoyang Gu, Liang Chen, Chen Chen   +10 more
doaj   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

Peach extract induces systemic and local immune responses in an experimental food allergy model

Scientific Reports, 2023
Peach allergy is among the most frequent food allergies in the Mediterranean area, often eliciting severe anaphylactic reactions in patients. Due to the risk of severe symptoms, studies in humans are limited, leading to a lack of therapeutic options ...
H. Steigerwald, M. Krause, I. Gonzalez-Menendez, L. Quintanilla-Martinez, S. Vieths, S. Scheurer, M. Albrecht, F. Blanco-Pérez   +7 more
doaj   +1 more source

RNA neoantigen vaccines prime long-lived CD8+ T cells in pancreatic cancer

Nature
A fundamental challenge for cancer vaccines is to generate long-lived functional T cells that are specific for tumour antigens. Here we find that mRNA–lipoplex vaccines against somatic mutation-derived neoantigens may solve this challenge in pancreatic ...
Z. Sethna, Pablo Guasp, Charlotte Reiche, Martina Milighetti, N. Ceglia, Erin Patterson, J. Lihm, George Payne, O. Lyudovyk, Luis A. Rojas, N. Pang, Akihiro Ohmoto, M. Amisaki, Abderezak Zebboudj, Z. Odgerel, Emmanuel M Bruno, Siqi Linsey Zhang, Charlotte Cheng, Y. Elhanati, E. Derhovanessian, Luisa Manning, Felicitas Müller, I. Rhee, Mahesh Yadav, T. Merghoub, J. Wolchok, O. Basturk, M. Gönen, Andrew S. Epstein, Parisa Momtaz, Wungki Park, R. Sugarman, A. Varghese, E. Won, A. Desai, Alice C. Wei, M. D'Angelica, T. Kingham, Kevin C Soares, W. Jarnagin, J. Drebin, E. O’Reilly, I. Mellman, U. Şahin, Ö. Türeci, Benjamin D. Greenbaum, Vinod P. Balachandran   +46 more
semanticscholar   +1 more source

Cancer Vaccines: Promising Therapeutics or an Unattainable Dream

Vaccines, 2021
The advent of cancer immunotherapy has revolutionized the field of cancer treatment and offers cancer patients new hope. Although this therapy has proved highly successful for some patients, its efficacy is not all encompassing and several cancer types ...
H. Donninger, Chi Li, J. Eaton, K. Yaddanapudi   +3 more
semanticscholar   +1 more source

Building a Framework for Sexual and Reproductive Health Care in the Rheumatology Context: Content and Approaches

Arthritis Care &Research, EarlyView.
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley   +1 more source

Functional properties and sequence variation of HTLV-1 p13

Retrovirology, 2020
Human T cell leukemia virus type-1 (HTLV-1) was the first retrovirus found to cause cancer in humans, but the mechanisms that drive the development of leukemia and other diseases associated with HTLV-1 infection remain to be fully understood. This review
Maria Omsland, Micol Silic-Benussi, Ramona Moles, Sarkis Sarkis, Damian F. J. Purcell, David Yurick, Georges Khoury, Donna M. D’Agostino, Vincenzo Ciminale, Genoveffa Franchini   +9 more
doaj   +1 more source