Results 21 to 30 of about 150,672 (260)
npj Vaccines, 2023 Development of SARS-CoV-2 vaccines that protect vulnerable populations is a public health priority. Here, we took a systematic and iterative approach by testing several adjuvants and SARS-CoV-2 antigens to identify a combination that elicits antibodies ...
Etsuro Nanishi +30 more
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Philosophical Transactions of the Royal Society B: Biological Sciences, 2011 Abstract While vaccines are primarily thought of in terms of their use for prevention of infectious diseases, they can potentially be used to prevent or treat cancer. This manuscript explores the rationale for vaccines and immunotherapies for cancer from both the scientific and the global needs perspectives.
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Aging, cancer, and cancer vaccines [PDF]
Immunity & Ageing, 2012 AbstractWorld population has experienced continuous growth since 1400 A.D. Current projections show a continued increase - but a steady decline in the population growth rate - with the number expected to reach between 8 and 10.5 billion people within 40 years.
MAZZOLA, PAOLO +6 more
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Isolation and characterization of cross-neutralizing coronavirus antibodies from COVID-19+ subjects
Cell Reports, 2021 Summary: SARS-CoV-2 is one of three coronaviruses that have crossed the animal-to-human barrier and caused widespread disease in the past two decades. The development of a universal human coronavirus vaccine could prevent future pandemics.
Madeleine F. Jennewein +28 more
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OncoImmunology, 2017 Purpose: Although local oncolytic viral therapy (OVT) may enhance tumor lysis, antigen release, and adaptive immune responses, systemic antitumor responses post-therapy are limited. Adoptive immunotherapy with autologous dendritic cells (DC) and cytokine-
Jun Ren +13 more
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Cancer Microenvironment and Cancer Vaccine [PDF]
Cancer Microenvironment, 2012 The cancer microenvironment is constituted of non-transformed host stromal cells such as endothelial cells, fibroblasts, various immune cells, and a complex extra-cellular matrix secreted by both the normal and neoplastic cells embedded in it. The importance of the microenvironment and its potential in cancer therapy is just being established.
Zhen-Yu, Ding +2 more
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PathogensThe transient depletion of monocytes alone prior to exposure of macaques to HTLV-1 enhances both HTLV-1WT (wild type) and HTLV-1p12KO (Orf-1 knockout) infectivity, but seroconversion to either virus is not sustained over time, suggesting a progressive ...
Anna Gutowska +12 more
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BMJ, 2015 Cancer vaccines are designed to promote tumor specific immune responses, particularly cytotoxic CD8 positive T cells that are specific to tumor antigens. The earliest vaccines, which were developed in 1994-95, tested non-mutated, shared tumor associated antigens that had been shown to be immunogenic and capable of inducing clinical responses in a ...
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Therapeutic cancer vaccines: Where do we stand?
Journal of Integrative Medicine and Research, 2023 Vaccines and immunotherapy have transformed the treatment modalities and prevention of several diseases including malignancy. Vaccines for infectious diseases have been in use for many decades, but very few cancer vaccines are approved for human use ...
Rajlaxmi Sarangi +4 more
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