Results 191 to 200 of about 286,222 (357)

Personalizing DNA Cancer Vaccines. [PDF]

J Pers Med
Wu AA, Peng K, Vukovich M, Zhu M, Lin Y, Bagga A, Wu TC, Hung CF.   +7 more
europepmc   +1 more source

Female Secondary School Students Sexual Exposure, Anti HPV Vaccine Awareness and Practice in High Cervical Cancer Prevalence Environment

, 2019
Mve Koh Valère, Essome Henri, Eta Vivian Enow Ayamba, T Marie   +3 more
openalex   +1 more source

Therapeutic cancer vaccine: phase I clinical tolerance study of Hu-rhEGF-rP64k/Mont in patients with newly diagnosed advanced non-small cell lung cancer [PDF]

, 2018
Puyuan Xing, Hongyu Wang, Sheng Yang, Xiaohong Han, Yan Sun, Yuankai Shi   +5 more
openalex   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Cancer vaccines: advances, hurdles, and future directions. [PDF]

Explor Target Antitumor Ther
Vlachostergios PJ.
europepmc   +1 more source

1034 Development of HLA class I expressing humanized patient-derived xenograft (hu-PDX) mouse models for the study of mRNA-based cancer vaccines in triple-negative breast cancer [PDF]

María F. Chervo, Wei Qian, Karina A. Ortega Martinez, Jianying Zhou, Raghav Shroff, Chiara Mancino, Leonardo Rojas, Francesca Taraballi, John P. Cooke, Jimmy Gollihar, Jenny C. Chang   +10 more
openalex   +1 more source

Soft‐Drug‐Inspired MnSTF Nano‐Adjuvant for Safe and Synergistic cGAS–STING Activation in Tumor Immunotherapy

Advanced Science, EarlyView.
This study introduces MnSTF, a soft‐drug‐inspired nanoadjuvant that overcomes the systemic toxicity of STING agonists. Through Mn2+ coordination with an ENPP1 inhibitor, it enables safe cGAS‐STING activation, remodels the tumor immune microenvironment, and synergizes with radiotherapy or vaccines to elicit robust antitumor immunity.
Guangfei Sun, Jiancheng Pan, Rui Li, Ruoxi Li, Ziyan Liu, Jinhui Wu, Tingsheng Lin, Yiqiao Hu, Ahu Yuan   +8 more
wiley   +1 more source

Therapeutic cancer vaccines in pancreatic cancer. [PDF]

Front Immunol
Wang Y, Huang P, Li C, Tu S, Yang H.
europepmc   +1 more source

Targeting DNA‐LNPs to Endothelial Cells Improves Expression Magnitude, Duration, and Specificity

Advanced Science, EarlyView.
Attaching antibodies against endothelial cell surface proteins redirects the delivery and expression of DNA‐lipid nanoparticles to organs of interest. Our targeted nanoparticles enable organ‐selective DNA expression in the endothelium of the lungs, brain, or spleen, providing a therapeutic platform for dozens of endothelial‐centric diseases.
Nicolas Marzolini, Taylor V. Brysgel, Ryan J. Rahman, Eno‐Obong Essien, Saw Y. Nwe, Jichuan Wu, Aparajeeta Majumder, Manthan N. Patel, Sachchidanand Tiwari, Carolann L. Espy, Fengyi Dong, Sabrina A. Santos‐De León, Anit Shah, Vladimir V. Shuvaev, Elizabeth D. Hood, Liam S. Chase, Drew Weissman, Jeremy B. Katzen, David B. Frank, Mariko L. Bennett, Oscar A. Marcos‐Contreras, Jacob W. Myerson, Vladimir R. Muzykantov, Sahily Reyes‐Esteves, Jacob S. Brenner   +24 more
wiley   +1 more source

Application of carbon nanotubes in cancer vaccines: Achievements, challenges and chances

, 2019
Hatem A. F. M. Hassan, Sandra S. Diebold, Lesley A. Smyth, Adam A. Walters, Giovanna Lombardi, Khuloud T. Al‐Jamal   +5 more
openalex   +1 more source