Results 301 to 310 of about 5,770,101 (353)
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Current Protocols in Human Genetics, 1997
AbstractThis unit describes the use of retroviral vectors that can be successfully employed for gene transfer into both primary tumor cultures and established cell lines. The unit includes procedures for assaying the stability of the vaccine following gene transfer.
T F, Greten, E M, Jaffee
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AbstractThis unit describes the use of retroviral vectors that can be successfully employed for gene transfer into both primary tumor cultures and established cell lines. The unit includes procedures for assaying the stability of the vaccine following gene transfer.
T F, Greten, E M, Jaffee
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mRNA Cancer Vaccines: Construction and Boosting Strategies.
ACS Nano, 2023In late 2020, the U.S. Food and Drug Administration (FDA) approved a lipid-based mRNA vaccine for the prevention of COVID-19, which has pushed this field to be more closely studied and motivated researchers to delve deeper into mRNA therapeutics. To date,
Xiaoqing Liu +3 more
semanticscholar +1 more source
Targeting tumor heterogeneity with neoantigen-based cancer vaccines.
Cancer Research, 2023Neoantigen-based cancer vaccines have emerged as a promising immunotherapeutic approach to treat cancer. Nevertheless, the high degree of heterogeneity in tumors poses a significant hurdle for developing a vaccine that targets the therapeutically ...
Saranya Pounraj +5 more
semanticscholar +1 more source
Science Translational Medicine, 2021
A nanovaccine based on bacterial cytoplasmic membranes and cell membranes from resected tumor tissue prevents tumor recurrence in mice. More effective personalized cancer vaccines Cancer-targeting vaccines are a promising therapy for patients after tumor
Long Chen +17 more
semanticscholar +1 more source
A nanovaccine based on bacterial cytoplasmic membranes and cell membranes from resected tumor tissue prevents tumor recurrence in mice. More effective personalized cancer vaccines Cancer-targeting vaccines are a promising therapy for patients after tumor
Long Chen +17 more
semanticscholar +1 more source
Hematology/Oncology Clinics of North America, 2019
Cancer vaccines are a promising strategic approach within the rapidly growing field of immuno-oncology. Therapeutic cancer vaccines are distinct from prophylactic vaccines and vary by both target antigen and vaccine platform. There are currently 3 FDA-approved therapeutic cancer vaccines: intravesical BCG live, sipuleucel-T, and T-VEC.
Peter J, DeMaria, Marijo, Bilusic
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Cancer vaccines are a promising strategic approach within the rapidly growing field of immuno-oncology. Therapeutic cancer vaccines are distinct from prophylactic vaccines and vary by both target antigen and vaccine platform. There are currently 3 FDA-approved therapeutic cancer vaccines: intravesical BCG live, sipuleucel-T, and T-VEC.
Peter J, DeMaria, Marijo, Bilusic
openaire +2 more sources
Cancer vaccines and the future of immunotherapy.
The LancetVaccines have had a major impact on the control of infectious disease, most recently by helping to combat the COVID-19 pandemic. Prophylactic cancer vaccines have prevented several malignancies by protecting against cancer-causing pathogens. By contrast,
O. Pail +4 more
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Recent advances and perspectives on the development of circular RNA cancer vaccines
npj VaccinesEngineered circular RNAs (circRNAs) are emerging as promising platforms for RNA-based vaccines in cancer treatment. We summarize the recent advances of design, synthesis, and delivery of circRNA-based cancer vaccines, and highlight the applications and ...
Zhaohui Gong +5 more
semanticscholar +1 more source
Next-generation cancer vaccines and emerging immunotherapy combinations.
Trends in CancerTherapeutic cancer vaccines have been a subject of research for several decades as potential new weapons to tackle malignancies. Their goal is to induce a long-lasting and efficient antitumour-directed immune response, capable of mediating tumour ...
A. Brandenburg, A. Heine, P. Brossart
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Current Gene Therapy, 2007
Cytotoxic chemotherapy is associated with modest survival advantage as initial treatment of advanced lung cancer. However, toxicity and minimal benefit to use second line treatment justifies exploration of alternative approaches. Recent understanding of mechanisms by which tumor antigen recognition can be enhanced has justified development of a recent ...
Rob, Eager +2 more
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Cytotoxic chemotherapy is associated with modest survival advantage as initial treatment of advanced lung cancer. However, toxicity and minimal benefit to use second line treatment justifies exploration of alternative approaches. Recent understanding of mechanisms by which tumor antigen recognition can be enhanced has justified development of a recent ...
Rob, Eager +2 more
openaire +2 more sources
Bioinspired and Biomimetic Delivery Platforms for Cancer Vaccines
Advances in Materials, 2021Cancer vaccines aim at eliciting tumor‐specific responses for the immune system to identify and eradicate malignant tumor cells while sparing the normal tissues.
Jing Liu, S. S. Liew, Jun Wang, Kanyi Pu
semanticscholar +1 more source