Results 11 to 20 of about 20,990 (167)

Protein interactome of the Cancerous Inhibitor of protein phosphatase 2A (CIP2A) in Th17 cells [PDF]

Current Research in Immunology, 2020
Cancerous inhibitor of protein phosphatase 2A (CIP2A) is involved in immune response, cancer progression, and Alzheimer's disease. However, an understanding of the mechanistic basis of its function in this wide spectrum of physiological and pathological ...
Mohd Moin Khan, Tommi Välikangas, Meraj Hasan Khan, Robert Moulder, Ubaid Ullah, Santosh Dilip Bhosale, Elina Komsi, Umar Butt, Xi Qiao, Jukka Westermarck, Laura L. Elo, Riitta Lahesmaa   +11 more
doaj   +6 more sources

Cancerous inhibitor of protein phosphatase 2A regulates cisplatin resistance in ovarian cancer. [PDF]

Oncol Lett, 2019
Ovarian cancer is the most aggressive type of gynecological cancer. The cause of the poor survival rate is the development of chemotherapy resistance to platinum-based therapies, including cisplatin.
Li W, Zhang H, Yang L, Wang Y.
europepmc   +5 more sources

Oncogenic nexus of cancerous inhibitor of protein phosphatase 2A (CIP2A): an oncoprotein with many hands. [PDF]

Oncotarget, 2014
Oncoprotein CIP2A a Cancerous Inhibitor of PP2A forms an “oncogenic nexus” by virtue of its control on PP2A and MYC stabilization in cancer cells. The expression and prognostic function of CIP2A in different solid tumors including colorectal carcinoma ...
De P, Carlson J, Leyland-Jones B, Dey N.
europepmc   +5 more sources

Cancerous Inhibitor of Protein Phosphatase 2A as a Molecular Marker for Aggressiveness and Survival in Oral Squamous Cell Carcinoma. [PDF]

J Cancer Prev, 2020
Cancerous inhibitor of protein phosphatase 2A (CIP2A) has been identified as one of the most commonly altered proteins in human cancers. It blocks the tumor-suppressive action of protein phosphatase 2A (PP2A) complex and enhances malignancy.
Alzahrani R, Alrehaili AA, Gharib AF, Anjum F, Ismail KA, Elsawy WH.   +5 more
europepmc   +4 more sources

MicroRNA-383-5p acts as a prognostic marker and inhibitor of cell proliferation in lung adenocarcinoma by cancerous inhibitor of protein phosphatase 2A. [PDF]

Oncol Lett, 2017
Lung cancer is the leading cause of cancer-associated mortality worldwide. MicroRNAs (miRNAs/miRs) serve a role in the occurrence and development of lung cancer. The aim of the present study was to analyze the expression and function of the proliferation-
Zhao S, Gao X, Zang S, Li Y, Feng X, Yuan X.   +5 more
europepmc   +5 more sources

Tamoxifen induces apoptosis through cancerous inhibitor of protein phosphatase 2A-dependent phospho-Akt inactivation in estrogen receptor-negative human breast cancer cells. [PDF]

Breast Cancer Res, 2014
IntroductionTamoxifen, a selective estrogen receptor (ER) modulator, may affect cancer cell survival through mechanisms other than ER antagonism. In the present study, we tested the efficacy of tamoxifen in a panel of ER-negative breast cancer cell lines
Liu CY, Hung MH, Wang DS, Chu PY, Su JC, Teng TH, Huang CT, Chao TT, Wang CY, Shiau CW, Tseng LM, Chen KF.   +11 more
europepmc   +6 more sources

Cancerous inhibitor of protein phosphatase 2A contributes to human papillomavirus oncoprotein E7-induced cell proliferation via E2F1. [PDF]

Oncotarget, 2015
Cancerous inhibitor of protein phosphatase 2A (CIP2A) is a recently identified oncoprotein that is overexpressed in many human malignant tumors including cervical cancer.
Zhang W, Chen H, Chen Y, Liu J, Wang X, Yu X, Chen JJ, Zhao W.   +7 more
europepmc   +4 more sources

MicroRNA-218 inhibits the cell proliferation and migration in clear cell renal cell carcinoma through targeting cancerous inhibitor of protein phosphatase 2A. [PDF]

Oncol Lett, 2019
MicroRNAs (miRs) have emerged as critical modulators of tumor initiation and progression in numerous types of human cancer, including clear cell renal cell carcinoma (ccRCC), which is the most common subtype of renal cell carcinoma.
Wei R, Ye X, Zhao Y, Jia N, Liu T, Lian W, Wei H, Zhang G, Song L.   +8 more
europepmc   +5 more sources

Expression of cancerous inhibitor of protein phosphatase 2A in human triple negative breast cancer correlates with tumor survival, invasion and autophagy. [PDF]

Oncol Lett, 2016
Cancerous inhibitor of protein phosphatase 2A (CIP2A) is a recently characterized oncoprotein which is involved in the progression of several human malignancies.
Li S, Feng TT, Guo Y, Yu X, Huang Q, Zhang L, Tang W, Liu Y.   +7 more
europepmc   +5 more sources

Erratum: [Corrigendum] Expression of cancerous inhibitor of protein phosphatase 2A in human triple negative breast cancer correlates with tumor survival, invasion and autophagy. [PDF]

Oncol Lett
[This corrects the article DOI: 10.3892/ol.2016.5374.].
Li S, Feng TT, Guo Y, Yu X, Huang Q, Zhang L, Tang W, Liu Y.   +7 more
europepmc   +3 more sources