Results 31 to 40 of about 34,909 (230)

Prevenção do Cancro do Colo do Útero

Onco.News, 2010
O cancro do colo do útero apresenta um importante impacto na vida das mulheres em todo o mundo, pois, embora o cancro seja mais frequente em pessoas idosas, o cancro do colo do útero afecta maioritariamente mulheres jovens, em idade activa, entre 35 e ...
Carla Alves dos Santos
doaj   +1 more source

Unraveling G‐Quadruplex and i‐Motif Coexistence Within a Double‐Stranded DNA

Angewandte Chemie, EarlyView.
The relative thermodynamic profiles of G‐quadruplex (G4), i‐Motif (iM), and the duplex counterpart tune the simultaneous G4 and iM formation within a double‐stranded (ds) DNA. ABSTRACT DNA can transiently fold into variable arrangements, which are expected to exploit regulatory functions. Guanine‐rich sequences can fold into G‐quadruplexes (G4s), while
Davide Auricchio, Michele Ghezzo, Uroš Zavrtanik, Luca Bertini, Valeria Libera, Riccardo Rigo, Jurij Lah, Claudia Sissi   +7 more
wiley   +2 more sources

A adaptação ao cancro da mama nas fases de diagnóstico e sobrevivência: Será o investimento na aparência um factor explicativo relevante? [PDF]

, 2011
O investimento na aparência é um factor importante na explicação das diferenças individuais na adaptação às alterações corporais associadas ao cancro da mama. Esta variável refere-se à importância atribuída pelo indivíduo à sua aparência física e engloba
Moreira, Helena, Agoglia, Bernardo Guiseppe, Almeida, Camila Rodrigues de, Elliot, Ligia Gomes, Morard, Maria Ribeiro Santos, Fiorelli, Rossano Kepler Alvim, Canavarro, Maria Cristina, Fiorelli, Stenio Karlos Alvim, Alvarenga, Regina Maria Papais   +8 more
core   +1 more source

Lay knowledge of cervical cancer in Manhiça district, Mozambique: a qualitative study

Reproductive Health, 2020
Resumo em Português Antecedentes Moçambique tem uma das maiores taxas de incidência de cancro do colo do útero no mundo. As intervenções de saúde para o cancro do colo do útero ainda têm sido concebidas apenas do ponto de vista de doenças não ...
Yara Alonso Menendez, Olga Cambaco, Carolina Mindú, Hoticha Nhantumbo, Titos Uamusse, Graça Matsinhe, Benigna Matsinhe, Rosa Marlene Manjate, Azucena Bardají, Clara Menendez, Esperança Sevene, Khátia Munguambe   +11 more
doaj   +1 more source

Analysis of sleep patterns in children with cancer and diabetes: associations with the psychological functioning of the child and the sleep quality of the mothers [PDF]

, 2022
openIl diabete mellito di tipo 1 è una malattia caratterizzata da una condizione di iperglicemia causata da una distruzione autoimmune delle cellule beta pancreatiche, le quali sono responsabili della produzione dell’insulina, un ormone che promuove il ...
CALVITTO, ANDREA
core  

Mitochondria‐Targeting Moieties Based on N‐Tethered Pyridinium Cations

Angewandte Chemie, EarlyView.
Pyridinium cations were benchmarked as mitochondria‐targeting moieties in a panel of N‐tethered fluorescent‐, bioactive‐, and inert‐cargo conjugates. 3,5‐Diphenylpyridinium (DPPy+) is a competent triphenylphosphonium (TPP+) surrogate, combining high mitochondria‐targeting efficiency with lower intrinsic effects on mitochondrial function.
Ivan Džajić, Natalija Trunkelj, Jernej Repas, Maša Kandušer, Lara Smrdel, Stane Pajk, Lovro Žiberna, Irena Mlinarič‐Raščan, Bostjan Markelc, Tim Bozic, Masa Omerzel, Tanja Jesenko, Maja Cemazar, Katja Kološa, Bojana Žegura, Miha Virant, Matic Lozinšek, Hai M. Nguyen, Joshua A. Nasburg, Heike Wulff, Maxime Gueguinou, Valerije Vrček, Veronica Carpanese, Ildiko Szabo, Luis A. Pardo, Tihomir Tomašič, Lucija Peterlin Mašič, Andrej Emanuel Cotman   +27 more
wiley   +2 more sources

Análise da Revisão Cochrane: Erradicação da Helicobacter pylori na Prevenção do Cancro Gástrico. Cochrane Database Syst Rev. 2015;7:CD005583.

Acta Médica Portuguesa, 2015
A infeção por Helicobacter pylori é um fator de risco para o desenvolvimento de cancro gástrico. A pesquisa e erradicação da Helicobacter pylori na população geral assintomática pode ser considerada para a prevenção primária do cancro gástrico, no ...
Diogo Libânio, Luís Filipe Azevedo
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source