Results 51 to 60 of about 34,996 (233)
Immune Markers and Risk of Pancreatic Cancer in the European EPIC Cohort
International Journal of Cancer, EarlyView.The immune system has been implicated as a major driver in pancreatic cancer etiology. Previous cohort studies have found associations between pancreatic cancer and single immune system‐derived markers, but omics‐based evidence remains scarce. In this prospective case–control study, the authors investigated 92 proteins involved in immune reactions and ...
Verena A. Katzke +28 more
wiley +1 more source
Revista de Enfermagem Referência, 2021 Contexto: O cancro está associado a perda e ameaça à vida, pelo que o seu diagnóstico configura carga emocional, tensão e sofrimento psicológico dos indivíduos e famílias, mediados por múltiplos fatores condicionantes dos processos adaptativos ...
Carla Alexandra Santos +3 more
doaj +1 more source
International Journal of Cancer, EarlyView.ABSTRACT Wilms Tumour (WT), the most common kidney cancer in children, presents features of altered kidney development and frequently exhibits molecular alterations at the 11p15.5 imprinted locus, affecting the IGF2 and H19 genes, which contribute to tumour growth and predisposition.
Abu Saadat +14 more
wiley +1 more source
Euromelanoma in Portugal 2010-2016
Revista da Sociedade Portuguesa de Dermatologia e Venereologia, 2018 Introdução: A incidência dos cancros da pele tem vindo a aumentar nos últimos anos em todo o mundo. O alerta das populações para a prevenção primária, promovendo o conhecimento sobre factores de risco e incentivando melhores comportamentos de proteção ...
Filipa Duarte +5 more
doaj +1 more source
The FGF/FGFR System in the Biology and Therapeutic Landscape of Pediatric CNS Tumors
Medicinal Research Reviews, EarlyView.ABSTRACT Central nervous system (CNS) tumors are the most common solid malignancies in children, comprising a highly heterogeneous group of neoplasms defined by distinct molecular alterations and clinical behaviors. Advances in molecular genetics have underscored the relevance of specific signaling pathways in driving pediatric tumorigenesis, among ...
Serena Filiberti +6 more
wiley +1 more source
Frontiers in Bioengineering and Biotechnology, 2015 The present work defines a modified critical size rabbit ulna defect model for bone regeneration in which a non-resorbable barrier membrane was used to separate the radius from the ulna to create a valid model for evaluation of tissue-engineered ...
Rania M El Backly +11 more
doaj +1 more source
The Journal of Pathology, EarlyView.Abstract Dedifferentiated endometrial carcinoma occurs when a prognostically favorable low‐grade endometrial carcinoma transforms into a highly aggressive undifferentiated carcinoma following genomic inactivation of core SWItch/Sucrose Non‐Fermentable (SWI/SNF) complex protein(s).
Antonio De Leo +15 more
wiley +1 more source
Journal of Orthopaedics and Traumatology, 2017 Background The purpose of this study was to summarize the available evidence about total lumbar disc replacement (TDR), focusing our attention on four main topics: clinical and functional outcomes, comparison with fusion surgery results, rate of ...
Matteo Formica +6 more
doaj +1 more source
Small, EarlyView.The study introduces a 3D sensing‐integrated platform enabling real‐time, non‐invasive monitoring of pH dynamics in patient‐derived PDAC tumorspheres. It revealed distinct extracellular acidification patterns under FOLFIRINOX, gemcitabine, and paclitaxel, correlating with therapeutic efficacy.
Stefania Forciniti +10 more
wiley +1 more source
Cancer Science, EarlyView.Comparison of extracellular vesicles with parental cells through proteomic profiling, followed by an integrated bioinformatic pipeline including disease association and transcriptomic analyses, identifies candidate biomarkers for multiple myeloma. Among these, MIF emerges as a clinically relevant marker, supported by validation in patient samples and ...
Natalia Platonova +13 more
wiley +1 more source