Results 41 to 50 of about 34,909 (230)
Obstipação induzida pelos opióides em doentes oncológicos adultos
Onco.News, 2017 Os opióides são o gold-standard para o tratamento da dor oncológica, mas alguns dos seus efeitos adversos podem comprometer o seu potencial terapêutico, como é o caso da obstipação.
Daniela Dias +5 more
doaj +1 more source
COMPLETE RESPONSE OF CUTANEOUS METASTASIS IN A MELANOMA PATIENT TREATED WITH IPILIMUMAB. [PDF]
Euromediterranean Biomedical Journal, 2012 We present the case of a 58 year old woman, who achieved complete response for her cutaneous melanoma metastasis after treatment with ipilimumab at 3 mg/Kg.
Francesco Spagnolo +3 more
doaj +1 more source
Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis
Molecular Oncology, EarlyView.LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini +1 more
wiley +1 more source
Characterization of the Ecosole HCPV tracker and single module inverter
, 2015 BECAR, the Beghelli group's RampD company, is leading ECOSOLE (Elevated COncentration SOlar Energy), one of the largest European Demonstration projects in solar photovoltaic.
Cancro, C., Graditi, G.
core +1 more source
Revista de Enfermagem Referência, 2021 Contexto: O cancro está associado a perda e ameaça à vida, pelo que o seu diagnóstico configura carga emocional, tensão e sofrimento psicológico dos indivíduos e famílias, mediados por múltiplos fatores condicionantes dos processos adaptativos ...
Carla Alexandra Santos +3 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.This study investigates the M13 bacteriophage as a biomimetic nanovector capable of crossing in vitro models of the blood–brain barrier. By exploiting peculiar transcellular pathways, M13 avoids lysosomal degradation and preserves its structural integrity and functionality.
Silvia Vercellino +12 more
wiley +1 more source
Advanced Science, EarlyView.An optimized ex vivo human liver slice culture system preserves tissue architecture, hepatocyte function, and immune‐stromal complexity for at least five days. By refining slice thickness, oxygenation, air‐liquid interface, and extracellular matrix support, the platform enables human‐relevant hepatotoxicity testing and mechanistic studies, offering a ...
Huiche Feng +17 more
wiley +1 more source
Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing
Advanced Science, EarlyView.Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale +6 more
wiley +1 more source
Terapia de grupo cognitivo-comportamental para sobreviventes de cancro da mama: Descrição de um programa e avaliação preliminar da sua eficácia [PDF]
, 2012 Objetivo: A terapia de grupo cognitivo-comportamental (TCC) tem-se mostrado altamente eficaz, nomeadamente no âmbito da psico-oncologia. Existem poucas descrições de como os programas para grupos de doentes de cancro podem ser estruturados e aplicados ...
Pereira, Anabela +2 more
core +1 more source
Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.Quantitative phase maps of single cells recorded in flow cytometry modality feed a hierarchical architecture of machine learning models for the label‐free identification of subtypes of ovarian cancer. The employment of a priori clinical information improves the classification performance, thus emulating the clinical application of liquid biopsy during ...
Daniele Pirone +11 more
wiley +1 more source