Treatment outcomes in pediatric intestinal failure patients with ambulatory Candida central line-associated bloodstream infections with and without central venous line removal: A retrospective case series. [PDF]
Abstract Background Lack of central venous line (CVL) sites is a common indication for intestinal transplantation in intestinal failure (IF) patients. For treatment of central line‐associated bloodstream infections (CLABSIs), many pediatric gastroenterologists preserve CVL access, but line removal is typically recommended for Candida sp CLABSI due to ...
Khan HH +5 more
europepmc +2 more sources
A single‐cell atlas of cerebrospinal fluid in Alzheimer's disease [PDF]
Abstract Background Potential differences in immune characteristics between sporadic late‐onset Alzheimer's disease (sLOAD) and sporadic late‐onset AD (sEOAD) have not been well elucidate. Immune cells in the cerebrospinal fluid (CSF) can reflect the brain immune system dysregulation of patients.
Lin J, Shi J.
europepmc +2 more sources
Multi-omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine. [PDF]
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Concetti L +10 more
europepmc +2 more sources
Different Role of CSF MMPs in Amyloid Pathology and Cerebrovascular Pathology [PDF]
Abstract Background Amyloid and cerebrovascular pathologies play critical role in the pathogenesis of Alzheimer's disease (AD). Matrix metalloproteinases (MMPs) is known to degrade Aβ peptides, while they also contribute to cerebrovascular pathology. Presently, the precise roles of MMPs in AD remain unclear.
Gao F, Zhan Y, Shen Y.
europepmc +2 more sources
CSF NPTXs sensitively monitor neurodegeneration and cognitive decline in the Alzheimer's disease continuum [PDF]
Abstract Background Identifying reliable and sensitive biomarkers to track neurodegeneration and cognitive impairment in Alzheimer's Disease (AD) is crucial for staging the severity of the disease. Method This study enrolled 435 participants from the China Aging and Neurodegenerative Disorder Initiative (CANDI) cohort from 2018 through 2023.
Dai L, Gao F, Shen Y.
europepmc +2 more sources
Cerebrospinal fluid NPTXR changes and relationships with β‐amyloid load and metabolism by PET in Alzheimer’s disease [PDF]
Abstract Background Neuronal pentraxin receptor (NPTXR) has been identified as a cerebrospinal fluid (CSF) biomarker associated with synaptic pathology, demonstrating its significant correlation with progressive cognitive impairment in Alzheimer’s disease (AD).
Ni M +5 more
europepmc +2 more sources
Penemuan sebuah candi Bata di daerah Pantura Jawa Tengah [PDF]
Penemuan Candi Kayen di Kabupaten Pati, menambah jumlah bangunan candi berbahan bata di Jawa Tengah. Penelitian yang pernah dilakukan Balai Arkeologi Yogyakarta sebelumnya, dilakukan di kawasan sekitar Borobudur.
Istari, T.M. Rita
core +2 more sources
Legenda Kolam Petirtaan di Kabupaten Mojokerto: Kajian Sosiologi Sastra Lisan
Oral stories in the form of legend which spread in Mojokerto, is one form of oral literature which is inherited from generation to generation. The study of the Legend of Kolam Petirtaan in Mojokerto includes three objects, namely: (1) Kolam Segaran, (2 ...
Icha Fadhilasari
doaj +1 more source
Cinta Merek Sebagai Mediasi Antara Kepercayaan Merek, Gairah Merek Dan Niat Beli Kembali
The purpose of this study was to examine the effect of brand passion, brand trust on repurchase intention and brand love as a mediating variable. Brand passion, brand trust and brand love directly have a significant and positive effect on repurchase ...
Kadarusman Kadarusman +2 more
doaj +1 more source
Candi Bumi Ayu Sebagai Bentuk Toleransi Beragama Pada Masa Kerajaan Sriwijaya Abad IX – XIII M
Tujuan penelitian ini adalah untuk mengetahui kehidupan keberagaman masyarakat dan kehidupan toleransi beragama pada candi Bumi Ayu di Kabupaten Pali. Metode penelitian ini menggunakan metode historis dimana terdapat langkah-langkah awal yaitu heuristik,
Kabib Sholeh, W. Wandiyo
doaj +1 more source

