Results 221 to 230 of about 89,333 (284)

Synthesis of Dendritic Oligo‐Glycerol Amphiphiles with Different Hydrophobic Segments to Improve their Performance as Nanocarriers

open access: yesChemistryOpen, EarlyView.
The synthesized dendritic oligoglycerol amphiphiles with different hydrophobic moieties show efficient micelle formation at low concentrations (CMC: 0.3–1.1 mg/mL) and a strong drug loading capacity, especially for Nile red and nimodipine. Long alkyl chains (C12) improve cargo encapsulation and biocompatibility, while release kinetics suggest potential
Pooja Kumari   +9 more
wiley   +1 more source

A 66‐Year‐old Woman With Submammary Brownish Hyperkeratotic Plaques

open access: yes
JEADV Clinical Practice, EarlyView.
Antonia Kössinger   +2 more
wiley   +1 more source

Studies Concerned with the Structure and Synthesis of the Anti‐viral Tropolone Glycoside Liriosmaside A

open access: yesChemistryOpen, EarlyView.
The core of the anti‐viral troponoid natural product liriosmaside A lacking the 3‐hydroxy‐3‐methylglutaric acid (HMGA) side‐chain at C6′ has been prepared. The early steps involved the gem‐dibromocyclopropane‐mediated ring‐expansion of a readily‐obtained Robinson annulation product.
Qi Chen   +9 more
wiley   +1 more source

Harnessing Molecular and Bioactivity Network Analysis to Prioritize Antibacterial Compound Isolation From Ant‐Associated Fungi

open access: yesPhytochemical Analysis, EarlyView.
ABSTRACT Introduction Antimicrobial resistance is a global public health problem that requires the development of new bioactive compounds. In this context, metabolomic analyses can expedite the research of fungal metabolites as a valuable resource. Objectives To investigate the metabolic profiles and isolate antibacterial compounds from micromycetes ...
Ángel S. Aguilar‐Colorado   +2 more
wiley   +1 more source

Investigation of antibacterial, antifungal, and antioxidant activities in novel poly(DEAEMA‐co‐EMA)/polyindole composites

open access: yesPolymer Engineering &Science, EarlyView.
Schematic illustration of prepared poly(DEAEMA‐co‐EMA)/PIN composities and 3D AFM image. Abstract In the current study, in the first stage, amphiphilic poly(2‐diethylamino ethylmethacrylate‐co‐ethyl methacrylate) [Poly(DEAEMA‐co‐EMA)] was synthesized from the 2‐diethylamino ethylmethacrylate (DEAEMA) and the ethyl methacrylate (EMA) using the free ...
Safiye Elif Korcan   +4 more
wiley   +1 more source

Pharmacokinetics of continuous infusion ceftolozane/tazobactam in two patients with extensive total body surface area burns

open access: yesPharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, EarlyView.
Abstract Introduction Treatment of infections in patients with burn injuries is challenging due to altered antimicrobial pharmacokinetics. Continuous infusion β‐lactam therapy may be a useful antimicrobial stewardship strategy to improve pharmacodynamic target attainment in this population.
Jay D. Olivet   +8 more
wiley   +1 more source

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