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Candida albicans proteinases [PDF]
Candida species are ubiquitous commensal yeast that usually reside as part of an individual´s normal mucosal microflora and can be detected in approximately 50% of the population in this form. However, if the balance of the normal flora is disrupted or the immune defences are compromised, Candida species can invade mucosal surfaces and cause disease ...
Rita de Cássia Mardegan+3 more
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IntroductionCandida albicans is the primary cause of systemic candidiasis, which is involved in high morbidity and mortality. Drug resistance exacerbates these problems. In addition, there are limited antifungal drugs available.
Xiuyun Li+6 more
doaj +1 more source
Gene flow contributes to diversification of the major fungal pathogen Candida albicans
Elucidating population structure and levels of genetic diversity and recombination is necessary to understand the evolution and adaptation of species. Candida albicans is the second most frequent agent of human fungal infections worldwide, causing high ...
J. Ropars+27 more
semanticscholar +1 more source
Candiduria: Prevalence and Trends in Antifungal Susceptibility in A Tertiary Care Hospital of Mangalore [PDF]
Objective: The incidence of Candida has been on rise worldwide. Urinary tract infections (UTIs) as a result of Candida species are becoming, common in hospitalised patients. Clinicians face dilemma in differentiating colonization from true candiduria.
Yashavanth R.+4 more
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Candida albicans induces mucosal bacterial dysbiosis that promotes invasive infection
Infectious complications are a common cause of morbidity and mortality in cancer patients undergoing chemotherapy due to increased risk of oral and gastrointestinal candidiasis, candidemia and septicemia. Interactions between C.
M. Bertolini+6 more
semanticscholar +1 more source
Background Vulvovaginal candidiasis is an important cause of morbidity among women due to Candida species. In the last decades, resistance to azoles, first-line antifungals has increased.
Essi Etonam Dovo+13 more
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Candida albicans pathogenicity mechanisms
The polymorphic fungus Candida albicans is a member of the normal human microbiome. In most individuals, C. albicans resides as a lifelong, harmless commensal. Under certain circumstances, however, C.
François L. Mayer+2 more
semanticscholar +1 more source
Oral potentially malignant disorders (OPMDs) refer to all epithelial lesions and conditions with an increased risk for malignant transformation, including oral leukoplakia, oral submucous fibrosis, oral lichen planus, erythroplakia, etc.
TONG Ting, CHENG Lei, REN Biao
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Candida albicans-Induced Epithelial Damage Mediates Translocation through Intestinal Barriers
Life-threatening systemic infections often occur due to the translocation of pathogens across the gut barrier and into the bloodstream. While the microbial and host mechanisms permitting bacterial gut translocation are well characterized, these ...
Stefanie Allert+16 more
semanticscholar +1 more source
Mucosal biofilms of Candida albicans [PDF]
Biofilms are microbial communities that form on surfaces and are embedded in an extracellular matrix. C. albicans forms pathogenic mucosal biofilms that are evoked by changes in host immunity or mucosal ecology. Mucosal surfaces are inhabited by many microbial species; hence these biofilms are polymicrobial.
Shantanu Ganguly, Aaron P. Mitchell
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