Results 41 to 50 of about 554,235 (252)

Pathological Signal‐Responsive Nanoplatforms for Sepsis: Integrating Biomarker Sensing With Spatiotemporal Drug Delivery and Immunomodulation

Advanced Science, EarlyView.
Biomarker‐triggered nanoplatforms transform sepsis therapy by coupling pathological sensing with precision drug release. This review reveals how microenvironment‐responsive nanomedicines enable stage‐specific intervention, improve therapeutic efficacy, and minimize systemic toxicity, while highlighting emerging opportunities for AI‐assisted and ...
Yukun Liu, Kang Wang, Kwet Kyawl Yan, Zhikai Xu, Xuan Zhao, Xiangjun Bai, Zhanfei Li, Yuchang Wang   +7 more
wiley   +1 more source

Effects of cationic antimicrobial peptides on Candida and Saccharomyces species [PDF]

, 2010
Electronic version does not contain associated previously published materialAntimicrobial peptides (AMPs) are found throughout the animal kingdom and act as a natural defence against a broad spectrum of pathogens.
Harris, Mark R.
core   +2 more sources

Efficacy and Safety of Nanoencapsulated Sirolimus Plus Pegadricase: Results From the Randomized, Placebo‐Controlled Phase 3 Trials

Arthritis &Rheumatology, EarlyView.
Objective DISSOLVE I and II examined the efficacy and safety of nanoencapsulated sirolimus (NAS) plus pegadricase (NASP) in patients with uncontrolled gout (UG). Methods In these double‐blind, placebo‐controlled Phase 3 trials of NASP, patients were randomized 1:1:1 to infusions of high‐dose (HD) or low‐dose (LD) NAS plus pegadricase (HD NASP, LD NASP,
Herbert S. B. Baraf, Puja P. Khanna, Milan Petronijevic, Mamuka Lortkipanidze, Anand Patel, Kwabena Ayesu, Michael H. Pillinger, Atul Singhal, Joanna Sobierska, Jacquie Christie, Peter Traber, Rehan Azeem, Wesley DeHaan, Hugues Santin‐Janin, Bhavisha Desai, Alan Kivitz   +15 more
wiley   +1 more source

Functional Characterization of the Small Heat Shock Protein Hsp12p from Candida albicans [PDF]

, 2012
Hsp12p is considered to be a small heat shock protein and conserved among fungal species. To investigate the expression of this heat shock protein in the fungal pathogen Candida albicans we developed an anti-CaHsp12p antibody.
Mühlschlegel, Fritz A., Fritz A. Mühlschlegel, De Sordi Luisa, Luisa De Sordi (146209), Fritz A. Mühlschlegel (146212), Fu Man-Shun, De Sordi, L, Fu, Man Shun, Fu, MS, Fritz A Mühlschlegel, Man-Shun Fu, Luisa De Sordi, Mühlschlegel Fritz A., De Sordi, Luisa, Mühlschlegel, FA, Luisa De Sordi¤b, Man-Shun Fu (146203)   +16 more
core   +1 more source

Intralesional Immunotherapy with Measles-Mumps-Rubella Vaccine for Recalcitrant Facial Warts: A Report of Two Cases

Oman Medical Journal, 2022
Warts are common benign skin tumors caused by human papilloma viruses. Recalcitrant facial warts tend to be cosmetically embarrassing to patients and difficult to treat for doctors.
Al Mutasim Al-Qassabi, Abdulrahman Al Kindi   +1 more
doaj   +1 more source

Beyond antimicrobials: Ecological nano‐strategies for rebalancing dysbiotic oral microbial homeostasis

BMEMat, EarlyView.
Oral microbial homeostasis, a dynamic host‐microbe balance, is vital in infectious diseases. Conventional antibiotics often disrupt this homeostasis, spurring interest in nanomaterials for oral microbial homeostasis rebalancing. This review outlines nanomaterial strategies across three ecological levels (population/community, ecosystem, and cross ...
Chen Hu, Aohan Luan, Yujun Yang, Linlin Wang, Huilin Wang, Ning Wang, Guixin He, Yajie Yang, Rabiya Noor, Jawad Hussain, Longquan Shao   +10 more
wiley   +1 more source

Antigenic cell wall mannoproteins in Candida albicans isolates and in other Candida species [PDF]

Journal of General Microbiology, 1991
Polyclonal antibodies (pAbs) and monoclonal antibodies (mAbs), raised against mannoprotein components from Candida albicans ATCC 26555 (serotype A) blastoconidia and mycelial cell walls, were used to investigate antigenic similarities among wall mannoproteins from other C. albicans serotype A and B strains, and from C. tropicalis and C. guilliermondii.
M L, Gil, M, Casanova, J P, Martínez, R, Sentandreu   +3 more
openaire   +2 more sources

Guidelines for Immunomodulatory Assays of Food Bioactives on Drosophila melanogaster Model

Future Postharvest and Food, EarlyView.
Guidelines are proposed for evaluating the immunomodulatory effects of food bioactives in Drosophila melanogaster, involving treatment with bioactives, pathogen preparation, infection routes, and immune response assessment. This model highlights the conserved mechanisms of cellular and humoral immunity for studying host‐microbe interactions.
Wenqi Huang, Shiye Lin
wiley   +1 more source

The Study of Immunological And Cytogenetic Effects of Polyvinyl Alcohol [PDF]

Engineering and Technology Journal, 2010
This study has been designed to investigate the toxicity effects ofpolyvinyl alcohol at different concentrations on peripheral blood lymphocytes by measuring each of blastogenic index, mitotic index and chromosomal aberration in addition to the polymorph
Falak O. Abas, Azhar M. Halim
doaj   +1 more source

Enzyme immunoassays for invasive Candida infections: reactivity of somatic antigens of Candida albicans [PDF]

Journal of Clinical Microbiology, 1991
The main problem encountered with serodiagnostic tests for Candida infections is their failure to differentiate between invasive and superficial candidosis. Recent immunoblotting studies suggested that the use of selective somatic proteins of Candida albicans as antigens might be a promising approach toward developing a new generation of serodiagnostic
L, Zöller, I, Krämer, R, Kappe, H G, Sonntag   +3 more
openaire   +2 more sources