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Candida auris is an emerging multidrug-resistant fungal pathogen reported worldwide. Infections due to C. auris are usually nosocomial and associated with high rates of fluconazole resistance and mortality.
Mahmoud Ghannoum +11 more
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Emergence of multidrug-resistant and opportunistic fungal infections due to Candida auris in intensive care units [PDF]
Background and Purpose: An increasing number of invasive infections due to multidrug-resistant Candida species have been reported worldwide. Among these Candida species, Candida auris has attracted more attention in recent years due to major outbreaks in
Peetam Singh, Anita Pandey
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Conserved Role for Biofilm Matrix Polysaccharides in
Candida auris has emerged as an outbreak pathogen associated with high mortality. Biofilm formation and linked drug resistance are common among Candida species. Drug sequestration by the biofilm matrix accounts for much of the antifungal tolerance.
E. G. Dominguez +6 more
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Exploring Candida auris in its habitat [PDF]
Candida auris colonizes human skin and causes life-threatening fungal bloodstream infections. In this issue of Cell Host & Microbe, Huang et al. introduce a murine model of C. auris skin colonization to explore the role of distinct clades, immune signaling pathways, antibiotics, and disinfectants on fungal persistence in or clearance from its habitat.
Bing, Zhai +2 more
openaire +2 more sources
A Synthetic β‐Mannan Epitope Enables Immunization and Detection of Candida auris
A synthetic β‐mannan epitope enables both active and passive immunization against Candida auris. Conjugation to the carrier protein CRM197 induces protective antibody responses, while monoclonal antibodies targeting the same epitope support detection using a lateral flow assay, linking glycochemistry with antifungal prevention and diagnostics ...
Emelie E. Reuber +8 more
wiley +2 more sources
Different efficacies of common disinfection methods against candida auris and other candida species
Background: Candida auris can form long-lasting colonies in the hospital environment and on human skin. There is limited evidence regarding the efficacy of different methods and products for disinfecting hospitals and colonized patients to prevent the ...
Leiwen Fu +7 more
doaj +1 more source
The occurrence of multidrug-resistant Candida auris isolates and the increased mortality associated with invasive infections or outbreaks due to this Candida species have been reported in many healthcare settings.
Elena De Carolis +8 more
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Candida auris: What Have We Learned About Its Mechanisms of Pathogenicity?
Candida auris has emerged globally as a multidrug-resistant (MDR) medical care-associated fungal pathogen. Recent reports have demonstrated that C. auris usually expresses fewer virulence factors than does Candida albicans.
Luana Rossato, Arnaldo Lopes Colombo
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Are we ready for the global emergence of multidrug-resistant Candida auris in Taiwan?
Candida auris is a recently identified multi-resistant Candida species, first reported in Japan in 2009, and poses a serious global health threat. Lack of awareness of this new Candida species and difficulties with laboratory identification have impacted
Po-Liang Lu +11 more
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IntroductionCandida auris is a recently discovered yeast with a multi-drug resistant profile associated with high mortality rates. The rapid identification of Candida auris in hospital settings is crucial to allow appropriate therapeutic and rapid ...
Arnaud Chalin +6 more
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