Results 51 to 60 of about 16,111 (225)

Identification of Drug Resistant Candida auris [PDF]

Frontiers in Microbiology, 2019
Candida auris is a multidrug resistant yeast, recognized as a cause of invasive infections and health care associated outbreaks around the world. C. auris is of great public health concern, due to its propensity for drug resistance, mode and pace of its transmission, and the possibility that biologic and epidemiologic factors could exacerbate worldwide
Milena Kordalewska, David S. Perlin
openaire   +3 more sources

Is Candida auris sexual?

PLOS Pathogens, 2020
We are grateful to Dr Gustavo Bravo Ruiz and Dr Delma Childers for critically reading the manuscript. Funding: We acknowledge funding from the Medical Research Council (MRC) Centre for Medical Mycology at the University of Exeter [grant number MR/P501955/1] (https://mrc.ukri.org/, https://www.exeter.ac.uk/medicalmycology/).
Zoe K. Ross, Alexander Lorenz
openaire   +5 more sources

Candida auris: Diagnostic challenges and outbreak control in paediatric and neonatal intensive care unit in a tertiary care hospital - the first of many in Eastern India

Clinical Epidemiology and Global Health
Problem considered: An emerging global threat, Candida auris infections have poor prognosis, high transmission rate, and potential for outbreaks. In India, prevalence of Candida auris invasive infection has been calculated to be 5.3 %.
K.P. Anirima, Prathyusha Kokkayil, Asim Sarfraz, Bhabesh Kant Chowdhry, Bhaskar Thakuria, Binod Kumar Pati   +5 more
doaj   +1 more source

Nucleic acids enrichment of fungal pathogens to study host-pathogen interactions [PDF]

, 2019
Fungal infections, ranging from superficial to life-threatening infections, represent a major public health problem that affects 25% of the worldwide population.
Coucke, Paul, Guillemyn, Brecht, Rodriguez Sánchez, Antonio, Vaneechoutte, Mario   +3 more
core   +1 more source

Candida auris: an Emerging Fungal Pathogen [PDF]

Journal of Clinical Microbiology, 2018
ABSTRACT Candida auris has emerged globally as a multidrug-resistant health care-associated fungal pathogen. Recent reports highlight ongoing challenges due to organism misidentification, high rates of antifungal drug resistance, and significant patient mortality.
Emily S, Spivak, Kimberly E, Hanson
openaire   +2 more sources

A Cationic Supramolecule With Potent Antifungal Activity, Single‐Species Selectivity, and Strong Synergy With Echinocandins

Advanced Science, EarlyView.
We introduce a new membrane‐active antifungal design, Gua‐SMACS‐16, that exhibits high potency and single‐species selectivity for C. tropicalis while sparing other close species in the Candida genus. Moreover, when combining with caspofungin, a clinical antifungal drug inhibiting 1,3‐β‐glucan synthase, they exhibit ultra‐strong synergy across a panel ...
Tianjiao Dai, Adrielle Xianwen Chen, Eve Wai Ling Chow, Li Mei Pang, Jianguo Li, Chandra Shekhar Verma, Stefan H. Oehlers, Yue Wang, Ning Li   +8 more
wiley   +1 more source

Epidemiologic Shift in Candidemia Driven by Candida auris, South Africa, 2016–2017

Emerging Infectious Diseases, 2019
Candida auris is an invasive healthcare-associated fungal pathogen. Cases of candidemia, defined as illness in patients with Candida cultured from blood, were detected through national laboratory-based surveillance in South Africa during 2016–2017.
Erika van Schalkwyk, Ruth S. Mpembe, Juno Thomas, Liliwe Shuping, Husna Ismail, Warren Lowman, Alan S. Karstaedt, Vindana Chibabhai, Jeannette Wadula, Theunis Avenant, Angeliki Messina, Chetna N. Govind, Krishnee Moodley, Halima Dawood, Praksha Ramjathan, Nelesh P. Govender   +15 more
doaj   +1 more source

Candida auris Forms High-Burden Biofilms in Skin Niche Conditions and on Porcine Skin

mSphere, 2020
Emerging pathogen Candida auris causes nosocomial outbreaks of life-threatening invasive candidiasis. It is unclear how this species colonizes skin and spreads in health care facilities. Here, we analyzed C.
Mark V. Horton, Chad J. Johnson, John F. Kernien, Tarika D. Patel, Brandon C. Lam, J. Z. Alex Cheong, Jennifer J. Meudt, Dhanansayan Shanmuganayagam, Lindsay R. Kalan, Jeniel E. Nett   +9 more
doaj   +1 more source

Differential skin immune responses in mice intradermally infected with Candida auris and Candida albicans

Microbiology Spectrum, 2023
Candida auris, an emerging multi-drug-resistant fungal pathogen, uniquely colonizes the human skin long term, leading to subsequent development of life-threatening invasive infections in humans. The factors regulating skin colonization of C.
Abhishek Datta, Diprasom Das, Jeniel E. Nett, Jatin M. Vyas, Michail S. Lionakis, Shankar Thangamani   +5 more
doaj   +1 more source

Sentinel Case of Candida auris in the Western United States Following Prolonged Occult Colonization in a Returned Traveler from India. [PDF]

, 2019
Candida auris is an emerging multidrug-resistant yeast with high mortality. We report the sentinel C. auris case on the United States West Coast in a patient who relocated from India.
Crawford, Emily D, Derisi, Joseph L, Doernberg, Sarah B, Dynerman, David, Langelier, Charles, Li, Lucy M, Lyden, Amy, Miller, Steve, Nichols, Amy, Ramirez-Avila, Lynn, Serpa, Paula Hayakawa, Tato, Cristina M, Woodworth, Michael H   +12 more
core   +1 more source