Results 51 to 60 of about 9,067 (180)

Phylogenetic and Structural Analysis of Miconazole Susceptibility in Malassezia pachydermatis Isolates From Dogs With Otitis Externa

Veterinary Dermatology, EarlyView.
ABSTRACT Background An increased number of dogs with unresolved yeast otitis externa (OE) after miconazole treatment was observed at a tertiary practice. Hypothesis/Objectives To evaluate miconazole susceptibility in Malassezia pachydermatis isolates from canine OE.
Cole M. Belcher, Clarissa P. Souza, Elyas McGuire, Chien‐Che Hung, Joel D. A. Tyndall, Lois L. Hoyer   +5 more
wiley   +1 more source

Prevalence of Antimicrobial Use in Small Animal Dermatology Referral Practices in the United States

Veterinary Dermatology, EarlyView.
ABSTRACT Background Antimicrobial resistance is a critical global health concern driven by antimicrobial use. Dermatological conditions are common reasons for antimicrobial prescriptions in small animal practice, yet data on prescribing patterns in veterinary dermatology referral settings are lacking. Hypothesis/Objectives To characterise the frequency,
Domenico Santoro, Emma R. Bollig, Jennifer L. Granick   +2 more
wiley   +1 more source

Novel Chromogenic Medium CHROMagar^TM Candida Plus for Detection of Candida auris and Other Candida Species from Surveillance and Environmental Samples: A Multicenter Study

Journal of Fungi, 2022
Epidemiological trends show a dramatic increase in the prevalence of fungal infections, and in the isolation of multidrug-resistant species, such as Candida auris.
Juan Vicente Mulet Bayona, Carme Salvador García, Nuria Tormo Palop, Amparo Valentín Martín, Carmelo González Padrón, Javier Colomina Rodríguez, Javier Pemán, Concepción Gimeno Cardona   +7 more
doaj   +1 more source

Frailty‐associated outcomes in geriatric emergency medicine ward patients: A retrospective cohort study informing program development

Hong Kong Journal of Emergency Medicine, Volume 33, Issue 4, August 2026.
Abstract Background Frail elderly patients require more interventions, and longer hospitalizations due to their complex health needs. The Emergency Medicine Ward (EMW) aims to provide acute care for patients with low‐acuity medical issues, often using a multidisciplinary approach for holistic care and discharge.
Tsz Kiu Chan, Man Ting Lau, Ka In Chan, Yuen Wa Ip, Wing Yuk Chan, Sze Yan Pui, Ying Ying Lam, Shing Ko, Oi Fung Wong, Sau Lai Chan, Candy Leung, Tsz Wah Patrick So, Po Fan Paul Chui, Wai Bik Geraldine Ng   +13 more
wiley   +1 more source

Intestinal colonization with Candida auris and mucosal immune response in mice treated with cefoperazone oral antibiotic

Frontiers in Immunology, 2023
Candida auris, an emerging multi-drug resistant fungal pathogen, causes invasive infections in humans. The factors regulating the colonization of C. auris in host niches are not well understood. In this study, we examined the effect of antibiotic-induced
Diprasom Das, Harm HogenEsch, Harm HogenEsch, Shankar Thangamani, Shankar Thangamani   +4 more
doaj   +1 more source

Effects of the HDAC6/8 Inhibitor MC1568, Alone and in Combination With Fluconazole, in Non‐Albicans Candida Species Infections

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
This study explores new antifungal strategies to combat non‐albicans Candida species. We tested clinically approved HDAC inhibitors—Vorinostat, Romidepsin, Tucidinostat—and the HDAC6/8‐selective MC1568, alone and with Fluconazole. The Fluconazole/MC1568 combination significantly enhanced antifungal activity and reduced biofilm formation.
Andrea Giammarino, Chiara Lambona, Alessia Raucci, Giovanna Simonetti, Salvatore Macrì, Angela Iuzzolino, Daniela Trisciuoglio, Sergio Valente, Gustavo Giusiano, Letizia Angiolella, Antonello Mai   +10 more
wiley   +1 more source

Analysis of Candida auris resistance and associated risk factors in hospitalized patients at a tertiary care hospital in China

Scientific Reports
Candida auris (Candidozyma auris, C. auris) is a significant concern in infection prevention. This study aims to analyze the antifungal susceptibility of C. auris isolates and risk factors of C.
Ting Fan, Zihuan Li, Zhenyao Zhao, Baohong Liu, Cuiqiong Fan, Tian Wang, Miao Yang, Yundao Li, Maorui Lin, Guanwen Lin   +9 more
doaj   +1 more source

From Oral Candidiasis to Candidemia: A Review of Superficial to Invasive Progression

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Recent and limited evidence indicates that oral candidiasis can disseminate Candida albicans throughout the body, leading to invasive candidiasis, such as candidemia, a life‐threatening infection. Considering antifungal resistance and global outbreaks of emergent non‐albicans Candida and related yeasts, murine models help understand dissemination ...
Julia Robledo Jerez, Marcella Vieira Ambrosio, Marcela Eduarda Olegario Fernandes, Ewerton Garcia de Oliveira Mima   +3 more
wiley   +1 more source

Candida auris: Epidemiology, biology, antifungal resistance, and virulence.

PLoS Pathogens, 2020
First described in 2009 in Japan, the emerging multidrug-resistant fungal pathogen Candida auris is becoming a worldwide public health threat that has been attracting considerable attention due to its rapid and widespread emergence over the past decade ...
Han Du, Jian Bing, Tianren Hu, Craig L Ennis, Clarissa J Nobile, Guanghua Huang   +5 more
doaj   +1 more source

A Cationic Supramolecule With Potent Antifungal Activity, Single‐Species Selectivity, and Strong Synergy With Echinocandins

Advanced Science, Volume 13, Issue 41, 22 July 2026.
We introduce a new membrane‐active antifungal design, Gua‐SMACS‐16, that exhibits high potency and single‐species selectivity for C. tropicalis while sparing other close species in the Candida genus. Moreover, when combining with caspofungin, a clinical antifungal drug inhibiting 1,3‐β‐glucan synthase, they exhibit ultra‐strong synergy across a panel ...
Tianjiao Dai, Adrielle Xianwen Chen, Eve Wai Ling Chow, Li Mei Pang, Jianguo Li, Chandra Shekhar Verma, Stefan H. Oehlers, Yue Wang, Ning Li   +8 more
wiley   +1 more source