Results 61 to 70 of about 1,379 (132)

Antifungal Susceptibility Profile and Biocide Tolerance in Clinically Relevant Yeasts: Implications for Therapy and Hospital Infection Control

Mycoses, Volume 69, Issue 9, September 2026.
ABSTRACT Background Opportunistic yeasts account for a substantial proportion of invasive fungal infections and are important agents of healthcare‐associated infections, especially in intensive care units (ICUs). Objectives To describe the clinical and epidemiological characteristics of hospitalized patients with positive cultures for medically ...
Yasmim Passos Lima, Letícia Rebello Machado, Ricardo Villela Bastos, Victor Quinet de Andrade Bastos, Lucas Quinet de Andrade Bastos, André Netto Bastos, Claudio Galuppo Diniz, Vania Lúcia da Silva, Vanessa Cordeiro Dias   +8 more
wiley   +1 more source

Environmental Contamination with Candida Species in Multiple Hospitals Including a Tertiary Care Hospital with a Candida auris Outbreak

Pathogens and Immunity, 2019
Background: Environmental sources have been implicated as a potential source for exogenous acquisition of Candida species, particularly the emerging multidrug-resistant Candida auris.
Jessica Ann Kumar, Brandon Eilertson, Jennifer L. Cadnum, Chauna S. Whitlow, Annette L. Jencson, Nasia Safdar, Sarah L. Krein, Windy D. Tanner, JeanMarie Mayer, Matthew H. Samore, Curtis J. Donskey   +10 more
doaj   +1 more source

Genotypes, Fluconazole Tolerance and Virulence Phenotypes of Candida albicans Bloodstream Isolates: A Multilocus Sequence Typing‐Based Analysis

Mycoses, Volume 69, Issue 9, September 2026.
ABSTRACT Background Fluconazole tolerance is an emerging phenotype in Candida albicans bloodstream infections, but its relationship to multilocus sequence typing (MLST) lineages and virulence traits is unclear. Objectives To investigate the relationships among MLST genotypes, fluconazole tolerance, and virulence phenotypes in C.
Shang‐Yi Lin, Yin‐Tse Huang, Ho‐Yin Huang, Wei‐Chun Hung, Yi‐Ting Tseng, Po‐Liang Lu   +5 more
wiley   +1 more source

Clinically Important Emerging and Uncommon Fungal Pathogens in Asia: Epidemiology, Antifungal Resistance and Challenges in Diagnosis and Management

Mycoses, Volume 69, Issue 9, September 2026.
ABSTRACT Fungal infections in Asia are influenced by warm, humid climates, high population density and expanding healthcare systems, which together facilitate the emergence, transmission and detection of both common and rare pathogens. While Candida and Aspergillus species remain the leading causes of invasive fungal disease, increasing attention has ...
Narut Chancharussin, Anupop Jitmuang, Arunaloke Chakrabarti, Methee Chayakulkeeree   +3 more
wiley   +1 more source

Structural Modifications of Nonsteroidal Anti‐Inflammatory Drugs (NSAIDs): New Horizons in Antimicrobial Drug Discovery

Archiv der Pharmazie, Volume 359, Issue 8, August 2026.
This review provides a comprehensive analysis of the molecular modifications applied to NSAIDs to develop novel antimicrobial agents. By focusing on structural changes and their impact on biological activity, the study highlights innovative strategies to combat the global challenge of antimicrobial resistance.
Ebru Koçak Aslan, Ayşe Karagüzel, Miyase Gözde Gündüz   +2 more
wiley   +1 more source

Thermogenic Characterization and Antifungal Susceptibility of Candida auris by Microcalorimetry

Journal of Fungi, 2019
Candida auris has emerged globally as a multidrug-resistant fungal pathogen. Isolates of C. auris are reported to be misidentified as Candida haemulonii. The aim of the study was to compare the heat production profiles of C.
Mariagrazia Di Luca, Anna Koliszak, Svetlana Karbysheva, Anuradha Chowdhary, Jacques F. Meis, Andrej Trampuz   +5 more
doaj   +1 more source

Frailty‐associated outcomes in geriatric emergency medicine ward patients: A retrospective cohort study informing program development

Hong Kong Journal of Emergency Medicine, Volume 33, Issue 4, August 2026.
Abstract Background Frail elderly patients require more interventions, and longer hospitalizations due to their complex health needs. The Emergency Medicine Ward (EMW) aims to provide acute care for patients with low‐acuity medical issues, often using a multidisciplinary approach for holistic care and discharge.
Tsz Kiu Chan, Man Ting Lau, Ka In Chan, Yuen Wa Ip, Wing Yuk Chan, Sze Yan Pui, Ying Ying Lam, Shing Ko, Oi Fung Wong, Sau Lai Chan, Candy Leung, Tsz Wah Patrick So, Po Fan Paul Chui, Wai Bik Geraldine Ng   +13 more
wiley   +1 more source

Candida auris: A Continuing Threat

Microorganisms
Candida auris is a World Health Organization critical-priority fungal pathogen that has variable resistance to antifungal treatments. Multiple clades have been identified through genomic analysis and have appeared in different geographic locations simultaneously.
Ashish Bhargava, Katherine Klamer, Mamta Sharma, Daniel Ortiz, Louis Saravolatz   +4 more
openaire   +3 more sources

Effects of the HDAC6/8 Inhibitor MC1568, Alone and in Combination With Fluconazole, in Non‐Albicans Candida Species Infections

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
This study explores new antifungal strategies to combat non‐albicans Candida species. We tested clinically approved HDAC inhibitors—Vorinostat, Romidepsin, Tucidinostat—and the HDAC6/8‐selective MC1568, alone and with Fluconazole. The Fluconazole/MC1568 combination significantly enhanced antifungal activity and reduced biofilm formation.
Andrea Giammarino, Chiara Lambona, Alessia Raucci, Giovanna Simonetti, Salvatore Macrì, Angela Iuzzolino, Daniela Trisciuoglio, Sergio Valente, Gustavo Giusiano, Letizia Angiolella, Antonello Mai   +10 more
wiley   +1 more source

Molecular Identification of Candida Species among Iranian Patients: Pursuing Candida auris

Advanced Biomedical Research
Background: Candida species are opportunistic pathogens that can cause local or systemic invasive infections in patients hospitalized in intensive care units (ICUs).
Fatemeh Safari, Mahboobeh Madani, Farshad Zare, Arman Ghahremanzadeh, Aydin Vaez, Hamid Morovati   +5 more
doaj   +1 more source