Results 61 to 70 of about 15,332 (223)

Candida auris Forms High-Burden Biofilms in Skin Niche Conditions and on Porcine Skin

mSphere, 2020
Emerging pathogen Candida auris causes nosocomial outbreaks of life-threatening invasive candidiasis. It is unclear how this species colonizes skin and spreads in health care facilities. Here, we analyzed C.
Mark V. Horton, Chad J. Johnson, John F. Kernien, Tarika D. Patel, Brandon C. Lam, J. Z. Alex Cheong, Jennifer J. Meudt, Dhanansayan Shanmuganayagam, Lindsay R. Kalan, Jeniel E. Nett   +9 more
doaj   +1 more source

Advancing Extracellular Vesicle Research: A Review of Systems Biology and Multiomics Perspectives

PROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound vesicles secreted by various cell types into the extracellular space and play a role in intercellular communication. Their molecular cargo varies depending on the cell of origin and its functional state.
Gloria Kemunto, Samaneh Ghadami, Kristen Dellinger   +2 more
wiley   +1 more source

Activity of rezafungin against Candida auris. [PDF]

J Antimicrob Chemother
Abstract The increasing prevalence of candidemia and invasive candidiasis infections caused by Candida auris represents a global health risk. Such infections are difficult to treat as they are often multidrug-resistant and are linked to high rates of mortality.
Locke JB, Andes D, Flanagan S, Redell M, Ong V, Aram JA, Pappas PG, Castanheira M, Thompson GR.   +8 more
europepmc   +3 more sources

International Survey on Antibiotic Prophylaxis Approaches for Solid Organ Transplant Recipients and Donors Colonized With Multidrug‐Resistant Organisms

Transplant Infectious Disease, EarlyView.
ABSTRACT Background Multidrug‐resistant organism colonization and infections cause significant morbidity and mortality in solid organ transplantation, affecting the perioperative antibiotic management. Yet, international practices for screening and antibiotic prophylaxis in colonized donors and recipients remain poorly defined.
Julia Bini Viotti, Stephanie M. Pouch, Maddalena Giannella, Monica Slavin, John W. Baddley, Ricardo M. La Hoz, Ligia Camera Pierrotti, Wanessa Trindade Clemente, Lilian M. Abbo   +8 more
wiley   +1 more source

Hog1 Regulates Stress Tolerance and Virulence in the Emerging Fungal Pathogen Candida auris

mSphere, 2018
Candida auris has recently emerged as an important, multidrug-resistant fungal pathogen of humans. Comparative studies indicate that despite high levels of genetic divergence, C.
Alison M. Day, Megan M. McNiff, Alessandra da Silva Dantas, Neil A. R. Gow, Janet Quinn   +4 more
doaj   +1 more source

Candida auris in skilled nursing facilities

Therapeutic Advances in Infectious Disease, 2023
Candida auris is a fungal organism resistant to several classes of antifungals. Since its identification in 2009, it has gained worldwide attention in healthcare for its virulence and resistance to commonly used antifungal therapeutics. Although its origin and mechanisms of transmission are not fully elucidated, it is widely recognized as a high ...
Philip S. Yune, Jared Coe, Mana Rao, Michael Y. Lin   +3 more
openaire   +2 more sources

Synergistic Antifungal Effects of Honokiol and Fluconazole Against Oral Candida: Implications for Managing Drug‐Resistant Infections

Clinical and Experimental Dental Research, Volume 12, Issue 1, February 2026.
ABSTRACT Objectives Antifungal drug resistance poses a major challenge in treating oral Candida infections. This study aimed to evaluate the antifungal activity of Honokiol, alone and combined with Fluconazole, against oral Candida isolates, and to investigate its mechanism of action via ergosterol biosynthesis inhibition and cell wall disruption ...
Maribasappa Karched, Mohammad Irshad, Jawad M. Behbehani   +2 more
wiley   +1 more source

Novel Chromogenic Medium CHROMagar^TM Candida Plus for Detection of Candida auris and Other Candida Species from Surveillance and Environmental Samples: A Multicenter Study

Journal of Fungi, 2022
Epidemiological trends show a dramatic increase in the prevalence of fungal infections, and in the isolation of multidrug-resistant species, such as Candida auris.
Juan Vicente Mulet Bayona, Carme Salvador García, Nuria Tormo Palop, Amparo Valentín Martín, Carmelo González Padrón, Javier Colomina Rodríguez, Javier Pemán, Concepción Gimeno Cardona   +7 more
doaj   +1 more source

Tumor Immunotherapy and Microbiome: From Bench‐to‐Bedside Applications

MedComm, Volume 7, Issue 2, February 2026.
The microbiome is related to the efficacy of immunotherapy and can be utilized to predict the efficacy and adverse reactions of immunotherapy. Microbiome‐targeted intervention strategies can improve the efficacy of ICI, but necessitating more comprehensive exploration.
Anqi Lin, Minying Xiong, Aimin Jiang, Li Chen, Lihaoyun Huang, Kailai Li, Hank Z. H. Wong, Jian Zhang, Zaoqu Liu, Quan Cheng, Bufu Tang, Pengpeng Zhang, Peng Luo   +12 more
wiley   +1 more source

Intestinal colonization with Candida auris and mucosal immune response in mice treated with cefoperazone oral antibiotic

Frontiers in Immunology, 2023
Candida auris, an emerging multi-drug resistant fungal pathogen, causes invasive infections in humans. The factors regulating the colonization of C. auris in host niches are not well understood. In this study, we examined the effect of antibiotic-induced
Diprasom Das, Harm HogenEsch, Harm HogenEsch, Shankar Thangamani, Shankar Thangamani   +4 more
doaj   +1 more source