Results 201 to 210 of about 29,327 (237)
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Evidence for recombination in Candida glabrata
Fungal Genetics and Biology, 2005Despite its clinical importance, little is known of the epidemiology and population structure of Candida glabrata. C. glabrata possesses a mating type system similar to that in Saccharomyces cerevisiae, however mating, meiosis and recombination have not been demonstrated.
Dodgson, Andrew R. +4 more
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Candida glabrata Spinal Osteomyelitis
The American Journal of the Medical Sciences, 2011Invasive disease caused by Candida spp. is being appreciated with increased frequency especially associated with widespread use of immunosuppressive drug therapy. We report a case of spinal osteomyelitis and epidural abscess caused by Candida glabrata occurring in a patient who had been diagnosed with candidemia 3 months before that patient was treated
Natalie J M, Dailey, Edward J, Young
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Azole Resistance in Candida glabrata
Current Infectious Disease Reports, 2016Candida infections have increased due to the growth and expansion of susceptible patient populations. The azole fluconazole is the most widely prescribed antifungal, but rising rates of clinical resistance among Candida glabrata isolates have greatly limited its utility.
Sarah G, Whaley, P David, Rogers
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Statin resistance in Candida glabrata
Biotechnology Letters, 2018Reduced efficacy of statins has been observed in people but the mechanism of this resistance is unclear and no statin-resistance mutations in the catalytic domain of HMGCR have been reported. The present study focused on looking for statin-resistance mutations and examining the mechanism of statin resistance using Candida glabrata as a model organism.C.
Mishal, Subhan +2 more
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Biguanides enhance antifungal activity against Candida glabrata [PDF]
Candida spp. are the fourth leading cause of nosocomial blood stream infections in North America. Candida glabrata is the second most frequently isolated species, and rapid development of antifungal resistance has made treatment a challenge.
Michael Mansour +2 more
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Biosynthesis of chemical compounds by Candida albicans and Candida glabrata
Revista Iberoamericana de Micología, 2019In the last three decades the species of Candida have been of great interest due to the high mortality rates that they cause in immunocompromised and hospitalized patients. These species are opportunistic pathogens and they have inhabited other environments long before colonizing human cells.
Abel, Moreno +2 more
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Microevolution of Candida glabrata (Nakaseomyces glabrata) during an infection
Fungal Genetics and BiologyCandida glabrata (Nakaseomyces glabrata) is an emergent and opportunistic fungal pathogen that colonizes and persists in different niches within its human host. In this work, we studied five clinical isolates from one patient (P7), that have a clonal origin, and all of which come from blood cultures except one, P7-3, obtained from a urine culture.
Ana L. López-Marmolejo +6 more
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Candida glabrata: a deadly companion?
Yeast, 2014AbstractThe yeast Candida glabrata has become a major fungal opportunistic pathogen of humans since the 1980s. Contrary to what its name suggests, it is much closer, phylogenetically, to the model yeast Saccharomyces cerevisiae than to the most prevalent human fungal pathogen, Candida albicans. Its similarity to S.
Monique, Bolotin-Fukuhara +1 more
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Candida nivariensis in comparison to different phenotypes of Candida glabrata
Mycoses, 2014SummaryThe purpose of the study was to establish the prevalence of new Candida glabrata complex species: Candida nivariensis and Candida bracarensis isolated from clinical material, evaluate their phenotypes and the prevalence of gene family encoding extracellular glycosylphosphatidylinositol‐linked aspartyl proteases, crucial for C. glabrata virulence.
Ewa Swoboda-Kopeć +5 more
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Management of infections caused by Candida glabrata
Current Infectious Disease Reports, 2000Candida glabrata infections undoubtedly have become more frequent, and are now common. They appear to be the consequence of widespread and often indiscriminate use of azoles, especially fluconazole. This species constitutes the Achilles heel of all available azoles, including newer ones in the pipeline.
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