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Statin resistance in Candida glabrata [PDF]

open access: possibleBiotechnology Letters, 2018
Reduced efficacy of statins has been observed in people but the mechanism of this resistance is unclear and no statin-resistance mutations in the catalytic domain of HMGCR have been reported. The present study focused on looking for statin-resistance mutations and examining the mechanism of statin resistance using Candida glabrata as a model organism.C.
Ian Macreadie   +3 more
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Candida (Torulopsis) glabrata

Infection Control, 1987
Candida (Torulopsis) glabratais a fungus with a diversity of habitats and an enlarging clinical spectrum. It is found as normal human flora in the gastrointestinal tract, skin, and vagina and also found in nature in soil and in animals. It was initially thought to represent a nonpathogenic saprophyte, however, it has been recovered with increasing ...
M P Sweeney   +2 more
openaire   +2 more sources

Candida glabrata Meningitis

Southern Medical journal, 1986
We have reported an unusual case of Candida glabrata meningitis causing acute changes in mental status in a chronically ill, elderly patient with non-insulin-dependent diabetes mellitus. Candida glabrata was identified by Gram stain, culture, and fermentation pattern from the CSF.
J Alvarez, E Anhalt, R Berg
openaire   +3 more sources

Evidence for recombination in Candida glabrata

Fungal Genetics and Biology, 2005
Despite its clinical importance, little is known of the epidemiology and population structure of Candida glabrata. C. glabrata possesses a mating type system similar to that in Saccharomyces cerevisiae, however mating, meiosis and recombination have not been demonstrated.
Dodgson, Andrew R.   +4 more
openaire   +4 more sources

Azole Resistance in Candida glabrata

Current Infectious Disease Reports, 2016
Candida infections have increased due to the growth and expansion of susceptible patient populations. The azole fluconazole is the most widely prescribed antifungal, but rising rates of clinical resistance among Candida glabrata isolates have greatly limited its utility.
P. David Rogers, Sarah G. Whaley
openaire   +2 more sources

Candida glabrata Spinal Osteomyelitis

The American Journal of the Medical Sciences, 2011
Invasive disease caused by Candida spp. is being appreciated with increased frequency especially associated with widespread use of immunosuppressive drug therapy. We report a case of spinal osteomyelitis and epidural abscess caused by Candida glabrata occurring in a patient who had been diagnosed with candidemia 3 months before that patient was treated
Natalie J.M. Dailey, Edward J. Young
openaire   +2 more sources

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