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Echinocandin-Resistenzen in \(Candida\) \(glabrata\)

2022
Candida glabrata ist die zweithäufigste Ursache von Candidämien und invasiven Hefepilzinfektionen in Europa. Im Gegensatz zu C. albicans zeigt C. glabrata eine reduzierte Empfindlichkeit gegen bestimmte Antimykotika und kann unter Therapie rasch Resistenzen entwickeln.
openaire   +1 more source

Candida glabrata: a deadly companion?

Yeast, 2014
AbstractThe yeast Candida glabrata has become a major fungal opportunistic pathogen of humans since the 1980s. Contrary to what its name suggests, it is much closer, phylogenetically, to the model yeast Saccharomyces cerevisiae than to the most prevalent human fungal pathogen, Candida albicans. Its similarity to S.
Cécile Fairhead   +1 more
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Biosynthesis of chemical compounds by Candida albicans and Candida glabrata

Revista Iberoamericana de Micología, 2019
In the last three decades the species of Candida have been of great interest due to the high mortality rates that they cause in immunocompromised and hospitalized patients. These species are opportunistic pathogens and they have inhabited other environments long before colonizing human cells.
Mayra Cuéllar-Cruz   +3 more
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Microevolution of Candida glabrata (Nakaseomyces glabrata) during an infection

Fungal Genetics and Biology
Candida glabrata (Nakaseomyces glabrata) is an emergent and opportunistic fungal pathogen that colonizes and persists in different niches within its human host. In this work, we studied five clinical isolates from one patient (P7), that have a clonal origin, and all of which come from blood cultures except one, P7-3, obtained from a urine culture.
Ana L. López-Marmolejo   +6 more
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Candida glabrata

Der Hautarzt, 2012
Chronic recurrent vulvovaginal candidiasis caused by Candida glabrata is still rare in comparison to C. albicans infection, but therapy remains more difficult. Standard agents as fluconazole or itraconazole often fail, as well as the newer systemic triazoles like voriconazole or posaconazole. Micafungin is a new echinocandin drug with a wide antifungal
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Management of infections caused by Candida glabrata

Current Infectious Disease Reports, 2000
Candida glabrata infections undoubtedly have become more frequent, and are now common. They appear to be the consequence of widespread and often indiscriminate use of azoles, especially fluconazole. This species constitutes the Achilles heel of all available azoles, including newer ones in the pipeline.
openaire   +3 more sources

Analysis of Subtelomeric Silencing in Candida glabrata

2011
Analysis of gene function often involves detailed studies of when a given gene is expressed or silenced. Transposon mutagenesis is a powerful tool to generate insertional mutations that provide with a selectable marker and a reporter gene that can be used to analyze the transcriptional activity of a specific locus in a variety of microorganisms to ...
Alejandro De Las Peñas   +2 more
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Parotid abscess by Candida glabrata

Medicina Clínica, 2020
Susana Arroyo Rodriguez   +2 more
openaire   +3 more sources

Candida glabrata prosthetic hip infection.

American journal of orthopedics (Belle Mead, N.J.), 2012
We present a case of a 60-year-old Caucasian woman carrying a 2-year-old hip prosthesis infected by Candida glabrata dose-dependent susceptible to fluconazole and voriconazole. Resection arthroplasty was performed. Six weeks of caspofungin plus liposomal amphotericin combination therapy achieved joint sterilization and allowed a successfully ...
Bartalesi F   +9 more
openaire   +2 more sources

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