Results 81 to 90 of about 44,509 (223)

Intensive care unit-related fluconazole use in Spain and Germany: patient characteristics and outcomes of a prospective multicenter longitudinal observational study [PDF]

, 2013
Background: Candida spp. are a frequent cause of nosocomial bloodstream infections worldwide. Objective: To evaluate the use patterns and outcomes associated with intravenous (IV) fluconazole therapy in intensive care units in Spain and Germany ...
Ballus, Jose, Bingold, Tobias Michael, Kaskel, Peter, Krobot, Karl J., Kumar, Ritesh N., Mavros, Panagiotis, Nocea, Gonzalo, Wissing, Heimo   +7 more
core   +1 more source

CRISPR/Cas9 Genome Engineering in Non‐Conventional Oleaginous Yeasts: Applications, Challenges, and Prospects

Yeast, EarlyView.
ABSTRACT Given the biotechnological potential of yeast‐derived oils for oleochemical production, genes encoding lipid metabolism enzymes are key targets for metabolic engineering. Genetic engineering tools such as Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9, Transcription Activator‐Like Effector Nucleases (TALENs), Zinc ...
Rodrigo Gonçalves Dias, Fernanda Pinheiro Moreira Freitas, Eduardo Luís Menezes de Almeida, Luciano Gomes Fietto, Agustin Zsögön, Wendel Batista da Silveira   +5 more
wiley   +1 more source

In vitro Antifungal Effect of Aqueous Garlic (Allium Sativum) Extract and its Combination with Fluconazole Against Five Common Clinical Candida Isolated from Candidiasis Lesions [PDF]

Journal of Kerman University of Medical Sciences, 2007
Introduction: Increasing rate of candidiasis prevalence and consequently use of antifungal drugs as prophylactic and curative agents has led to the widespread emergence of resistant strains.
A.A Jafari Nodoushan, M Dehghani, S.M Mirbagheri   +2 more
doaj  

Pre-exposure to Candida glabrata protects Galleria mellonella against subsequent lethal fungal infections

Virulence, 2020
Commensal fungi are an important part of human microbial community, among which Candida albicans and Candida glabrata are two common opportunistic pathogens. Unlike the high pathogenicity of C. albicans, C.
Xiao-Wen Huang, Mei-Nian Xu, Huan-Xin Zheng, Meng-Lei Wang, Li Li, Kang Zeng, De-Dong Li   +6 more
doaj   +1 more source

Platelet‐Rich Fibrins as Local Drug‐Delivery Carriers

Journal of Periodontal Research, EarlyView.
Autologous platelet concentrates (APCs), particularly platelet‐rich fibrin (PRF), act as biologically active fibrin scaffolds, capable of entrapping and gradually releasing therapeutic agents in oral and periodontal therapy. The incorporation of bioactive compounds, such as antibiotics, antifungals, vitamins, antidiabetic drugs, and exosomes, enhances ...
Karim M. Fawzy El‐Sayed, Christof E. Dörfer   +1 more
wiley   +1 more source

Calli Essential Oils Synergize with Lawsone against Multidrug Resistant Pathogens. [PDF]

, 2017
The fast development of multi-drug resistant (MDR) organisms increasingly threatens global health and well-being. Plant natural products have been known for centuries as alternative medicines that can possess pharmacological characteristics, including ...
Alsaadi, Abrar I, Husseiny, Mohamed I, Ibrahim, Ashraf S, Khitrov, Gregory, Noreddin, Ayman M, Soliman, Sameh SM, Youssef, Eman G   +6 more
core   +2 more sources

Performance of the BioFire FilmArray Pneumonia Panel Plus Compared to Standard Microbiology in Lung Transplant Donor and Recipient Samples: A Prospective Cohort Study

Transplant Infectious Disease, EarlyView.
A prospective study demonstrating that the BioFire Pneumonia Panel Plus shows substantial concordance with culture in donor samples and moderate concordance in recipient samples, supporting its potential role in guiding perioperative antibiotic prophylaxis in lung transplantation.
Andrea Lombardi, Giulia Renisi, Lorenzo Rosso, Letizia Morlacchi, Jacopo Fumagalli, Lisa Cariani, Ilaria Righi, Valeria Rossetti, Arianna Liparoti, Cecilia Azzarà, Davide Mangioni, Laura Alagna, Paola Saltini, Maria Francesca Liporace, Chiara Abbruzzese, Annapaola Callegaro, Francesco Blasi, Giacomo Grasselli, Mario Nosotti, Alessandra Bandera   +19 more
wiley   +1 more source

Candida albicans biofilm heterogeneity does not influence denture stomatitis but strongly influences denture cleansing capacity [PDF]

, 2017
Approximately 20  % of the UK population wear some form of denture prosthesis, resulting in denture stomatitis in half of these individuals. Candida albicans is primarily attributed as the causative agent, due to its biofilm -forming ability.
Allen, Christopher J. Nile, Craig Williams, David F. Lappin, Douglas Robertson, Gareth Calvert, Gordon Ramage, Hasanain K. A. Alalwan, Leighann Sherry, Lindsay E. O’Donnell, Newton, Paranhos, Park, Pavarina, Radford, Ryan Kean, Salerno, Shulman, Wright   +18 more
core   +2 more sources

Phenotypic switching and filamentation in Candida glabrata [PDF]

Microbiology, 2002
Candida glabrata switches spontaneously, reversibly and at high frequency among the following four phenotypes distinguishable by graded colony colouration on CuSO(4)-containing agar: white (Wh), light brown (LB), dark brown (DB) and very dark brown (vDB). These phenotypes also differ in a graded fashion in the level of expression of the metallothionein
Salil A, Lachke, Sophie, Joly, Karla, Daniels, David R, Soll   +3 more
openaire   +2 more sources

An Update on Invasive Fungal Infections in Solid Organ Transplant Recipients

Transplant Infectious Disease, EarlyView.
ABSTRACT Invasive fungal infections (IFI) remain a significant infection‐related complication in solid organ transplant recipients (SOTRs), the incidence of which has not changed overtime. With a focus on studies and data published after 2019, this narrative review provides an update on the epidemiology and prevention of IFIs in SOTRs and highlights ...
Tina Marinelli, Shahid Husain
wiley   +1 more source