Results 61 to 70 of about 45,050 (233)

The Lack of SNARE Protein Homolog Syn8 Influences Biofilm Formation of Candida glabrata

Frontiers in Cell and Developmental Biology, 2021
Biofilm formation of Candida species is considered to be a pathogenic factor of host infection. Since biofilm formation of Candida glabrata has not been as well studied as that of Candida albicans, we performed genetic screening of C. glabrata, and three
Xinyue Chen, Shun Iwatani, Toshitaka Kitamoto, Hiroji Chibana, Susumu Kajiwara   +4 more
doaj   +1 more source

Antimicrobial Activities and Mechanisms of Magnesium Oxide Nanoparticles (nMgO) against Pathogenic Bacteria, Yeasts, and Biofilms. [PDF]

, 2018
Magnesium oxide nanoparticle (nMgO) is a light metal based antimicrobial nanoparticle that can be metabolized and fully resorbed in the body. To take advantage of the antimicrobial properties of nMgO for medical use, it is necessary to determine the ...
Grelling, Nathaniel, Liu, Huinan, Nguyen, Nhu-Y Thi, Rosario, Romeo, Wetteland, Cheyann Lee   +4 more
core   +3 more sources

Use of Clotrimazole in Finfish Aquaculture: Mechanistic Insights, Limitations, and Future Directions for Antifungal Therapy

Animal Research and One Health, EarlyView.
This review critically evaluates clotrimazole as a potential antifungal for finfish aquaculture, highlighting strong mechanistic and in vitro efficacy against aquatic mycoses alongside major gaps in in vivo evidence, toxicokinetics, residue safety, and environmental risk, outlining priorities for responsible therapeutic development and regulatory ...
Arya Sen, Debashri Mondal, Thangapalam Jawahar Abraham   +2 more
wiley   +1 more source

Anidulafungin for Candida glabrata Infective Endocarditis [PDF]

Antimicrobial Agents and Chemotherapy, 2012
Sir, we briefly report on a patient with infective endocarditis (IE) by Candida glabrata treated with double-dosage of anidulafungin.…
De Rosa F. G., D'Avolio A., Corcione S., Baietto L., Raviolo S., Centofanti P., Pasero D., Rinaldi M., Di Perri G.   +8 more
openaire   +2 more sources

Mechanisms underlying the exquisite sensitivity of Candida albicans to combinatorial cationic and oxidative stress that enhances the potent fungicidal activity of phagocytes [PDF]

, 2014
Copyright © 2014 Kaloriti et al.Peer reviewedPublisher ...
Bohovych, Iryna, Brown, Alistair J P, Cook, Emily, Gow, Neil A R, Grebogi, Celso, Grimm, Melissa J, Haynes, Ken, Jacobsen, Mette, Kaloriti, Despoina, Patterson, Miranda, Quinn, Janet, Segal, Brahm H, Smith, Deborah A, Tillmann, Anna, Yin, Zhikang, You, Tao   +15 more
core   +2 more sources

Fungal Antimicrobial Resistance: Mechanisms, Drivers, and Global Clinical Burden

ChemFoodChem, EarlyView.
ABSTRACT Fungal antimicrobial resistance (AMR) is a growing concern for world health caused by an increase in multidrug‐resistant infections, an increase in environmental reservoirs, and the ineffectiveness of current antifungal treatments. Fungal infections continue to be largely excluded from AMR initiatives while causing over 1.6 million deaths ...
Bikash Baral
wiley   +1 more source

Lactate signalling regulates fungal β-glucan masking and immune evasion [PDF]

, 2016
AJPB: This work was supported by the European Research Council (STRIFE, ERC- 2009-AdG-249793), The UK Medical Research Council (MR/M026663/1), the UK Biotechnology and Biological Research Council (BB/K017365/1), the Wellcome Trust (080088; 097377).
A Hopke, B Ferwerda, BN Gantner, C Kuei, CA Johnston, CA Munro, CA Rappleye, CJ Barelle, CJ Heilmann, DH Owen, DO Inglis, E Leberer, FN Gravelat, G Bindea, GD Brown, GJ Sosinska, HJ Flint, I Jacobs, ID Iliev, IV Ene, IV Ene, IV Ene, IV Ene, JE Nett, JM Bain, K Lemaire, LE Lewis, LM Graham, M Galán-Díez, M Karababa, M Santos, MG Netea, MG Netea, MJ Marakalala, MM Maidan, MT Kelly, N Vieira, NAR Gow, P Shannon, PR Desai, RA Hall, RT Wheeler, RT Wheeler, RT Wheeler, S Lev, S Shahana, SdJ Carrion, SE Hardison, SM Noble, TR O'Meara, YL Chen   +50 more
core   +1 more source

Antioxidant and Cytotoxic Properties of Piper spp. Volatile Oils That Inhibit Pathogenic Microorganisms

Flavour and Fragrance Journal, EarlyView.
The samples were fungicidal against Candida, with MICs ranging from 62.5 to 250 μg/mL, and fungistatic against Penicillium adametzii, Aspergillus flavus and A. niger, with MICs of 1000 μg/mL. The volatile oils of Piper aduncum and Piper marginatum reduced the viability of MDA‐MB231 cells.
Midiã R. Oliveira, Ely D. Alfaia Neto, Carlos Eduardo C. Alves, Renata Galvão de Azevedo, Alice F. Gomes, Flávia Juliana Reis de Sousa, Juan Campos de Oliveira, Larissa Raquel S. Maciel, Gemilson S. Pontes, Ari F. Hidalgo, Antonia Q. L. Souza, Rita C. Saraiva Nunomura   +11 more
wiley   +1 more source

Candida glabrata displays pseudohyphal growth [PDF]

FEMS Microbiology Letters, 2000
The ability to undergo morphological change has been reported as an advantageous trait in fungal pathogenesis. Here we demonstrate that Candida glabrata ATCC2001, like diploid Saccharomyces cerevisiae strains, forms elongated chains of pseudohyphal cells on solid nitrogen starvation media (SLAD).
Ken Haynes, Csilla Csank
openaire   +4 more sources

Ibrexafungerp, a Novel Oral Triterpenoid Antifungal in Development: Overview of Antifungal Activity Against Candida glabrata

Frontiers in Cellular and Infection Microbiology, 2021
Systemic infections caused by Candida species are an important cause of morbidity and mortality among immunocompromised and non-immunocompromised patients.
Ahmed Gamal, Sherman Chu, Sherman Chu, Thomas S. McCormick, Katyna Borroto-Esoda, David Angulo, Mahmoud A. Ghannoum, Mahmoud A. Ghannoum   +7 more
doaj   +1 more source