Results 51 to 60 of about 44,509 (223)

Oropharyngeal Candida Colonization in Patients with Acute Myeloid Leukemia

Frontiers in Dentistry, 2020
Objectives: Oral candidiasis has increased in recent years because of the increasing number of high-risk populations. The prevalence of Candida species is different worldwide because of the difference between population characteristics, sampling ...
Shiva Shirazian, Soheila Manifar, Reza Safaei Nodehi, Mohaddeseh Shabani   +3 more
doaj   +1 more source

Fungi at the scene of the crime: innocent bystanders or accomplices in oral infections? [PDF]

, 2018
Purpose of Review: Over the last decade, microbiome studies have enhanced our knowledge and understanding of the polymicrobial nature of oral infections.
Delaney, Christopher, Kean, Ryan, McLean, William, Nile, Christopher, Ramage, Gordon, Short, Bryn, Tumelty, Maria   +6 more
core   +2 more sources

Differential Virulence of Candida glabrata Glycosylation Mutants [PDF]

Journal of Biological Chemistry, 2013
The fungus Candida glabrata is an important and increasingly common pathogen of humans, particularly in immunocompromised hosts. Despite this, little is known about the attributes that allow this organism to cause disease or its interaction with the host immune system. However, in common with other fungi, the cell wall of C.
West, L., Lowman, D.W., Mora-Montes, H.M., Grubb, S., Murdoch, C., Thornhill, M.H., Gow, N.A.R., Williams, D., Haynes, K.   +8 more
openaire   +4 more sources

Phosphate in Virulence of Candida albicans and Candida glabrata [PDF]

Journal of Fungi, 2020
Candida species are the most commonly isolated invasive human fungal pathogens. A role for phosphate acquisition in their growth, resistance against host immune cells, and tolerance of important antifungal medications is becoming apparent. Phosphorus is an essential element in vital components of the cell, including chromosomes and ribosomes. Producing
Julia R. Köhler, Maikel Acosta-Zaldívar, Wanjun Qi   +2 more
openaire   +3 more sources

A Cationic Supramolecule With Potent Antifungal Activity, Single‐Species Selectivity, and Strong Synergy With Echinocandins

Advanced Science, EarlyView.
We introduce a new membrane‐active antifungal design, Gua‐SMACS‐16, that exhibits high potency and single‐species selectivity for C. tropicalis while sparing other close species in the Candida genus. Moreover, when combining with caspofungin, a clinical antifungal drug inhibiting 1,3‐β‐glucan synthase, they exhibit ultra‐strong synergy across a panel ...
Tianjiao Dai, Adrielle Xianwen Chen, Eve Wai Ling Chow, Li Mei Pang, Jianguo Li, Chandra Shekhar Verma, Stefan H. Oehlers, Yue Wang, Ning Li   +8 more
wiley   +1 more source

Synergistic Interactions between Pseudomonas aeruginosa and Candida albicans, Candida glabrata, Candida krusei, Candida parapsilosis as well as Candida tropicalis in the Formation of Polymicrobial Biofilms

Journal of Pure and Applied Microbiology
The interactions between pathogens during infection and the impact of these interactions on drug effectiveness are poorly understood, making polymicrobial infections challenging to treat. During an infection, cross-interactions between bacteria and fungi
Yenni Andriana, Agung Dwi Wahyu Widodo, Muhammad Vitanata Arfijanto   +2 more
doaj   +1 more source

Lactate signalling regulates fungal β-glucan masking and immune evasion [PDF]

, 2016
AJPB: This work was supported by the European Research Council (STRIFE, ERC- 2009-AdG-249793), The UK Medical Research Council (MR/M026663/1), the UK Biotechnology and Biological Research Council (BB/K017365/1), the Wellcome Trust (080088; 097377).
A Hopke, B Ferwerda, BN Gantner, C Kuei, CA Johnston, CA Munro, CA Rappleye, CJ Barelle, CJ Heilmann, DH Owen, DO Inglis, E Leberer, FN Gravelat, G Bindea, GD Brown, GJ Sosinska, HJ Flint, I Jacobs, ID Iliev, IV Ene, IV Ene, IV Ene, IV Ene, JE Nett, JM Bain, K Lemaire, LE Lewis, LM Graham, M Galán-Díez, M Karababa, M Santos, MG Netea, MG Netea, MJ Marakalala, MM Maidan, MT Kelly, N Vieira, NAR Gow, P Shannon, PR Desai, RA Hall, RT Wheeler, RT Wheeler, RT Wheeler, S Lev, S Shahana, SdJ Carrion, SE Hardison, SM Noble, TR O'Meara, YL Chen   +50 more
core   +1 more source

Use of Clotrimazole in Finfish Aquaculture: Mechanistic Insights, Limitations, and Future Directions for Antifungal Therapy

Animal Research and One Health, EarlyView.
This review critically evaluates clotrimazole as a potential antifungal for finfish aquaculture, highlighting strong mechanistic and in vitro efficacy against aquatic mycoses alongside major gaps in in vivo evidence, toxicokinetics, residue safety, and environmental risk, outlining priorities for responsible therapeutic development and regulatory ...
Arya Sen, Debashri Mondal, Thangapalam Jawahar Abraham   +2 more
wiley   +1 more source

Candida and Porphyromonas gingivalis: the effect on wound closure in vitro

Journal of Oral Microbiology, 2017
Microorganisms play a role in oral mucositis after cancer therapy. The current study explored the hypothesis that Candida spp. alone and together with Porphyromonas gingivalis cause delayed healing of oral ulcerations due to the inhibition of wound ...
Thijs M. Haverman, Alexa M. G. A. Laheij, Johannes J. de Soet, Jan de Lange, Frederik R. Rozema   +4 more
doaj   +1 more source

Essential metals at the host-pathogen interface : nutritional immunity and micronutrient assimilation by human fungal pathogens [PDF]

, 2015
AC and DW are supported by a Sir Henry Dale Fellowship jointly funded by the Wellcome Trust and the Royal Society (Grant Number 102549/Z/13/Z).Peer reviewedPublisher ...
Crawford, Aaron, Wilson, Duncan
core   +1 more source