A case is reported of Candida glabrata microbial invasion of the amniotic cavity and maternal candidemia with a negative 1,3-β-D-glucan test. A 28-year-old singleton pregnant woman (gravida 1, para 0) presented at 18 weeks and 3 days of gestation ...
Michihisa Shiro +3 more
doaj +1 more source
CO(2) acts as a signalling molecule in populations of the fungal pathogen Candida albicans. [PDF]
When colonising host-niches or non-animated medical devices, individual cells of the fungal pathogen Candida albicans expand into significant biomasses. Here we show that within such biomasses, fungal metabolically generated CO(2) acts as a communication
Topal Hüsnü +69 more
core +1 more source
Rapid identification of Candida glabrata in Candida bloodstream infections [PDF]
Candida species are the fourth most common cause of bloodstream infection (BSI) in the hospitalized patient. Candida glabrata is the most common non-Candida albicans Candida species in England and Wales with an attributed mortality of 48 %. C.
Nicholas, Foster +3 more
openaire +2 more sources
Antifungal activity of the non cytotoxic human peptide hepcidin 20 against fluconazole resistant Candida glabrata in human vaginal fluid [PDF]
Vaginal infections due to Candida glabrata are difficult to eradicate, due to the scarce susceptibility to azoles of this species. Previous studies have shown that the human cationic peptide hepcidin 20 (Hep-20) exerts fungicidal activity in sodium ...
Semih Esin +16 more
core +1 more source
Denture stomatitis (DS) is a condition characterized by inflammation of the oral mucosa in direct contact with dentures and affects a significant number of otherwise healthy denture wearers.
Junko Yano +3 more
doaj +1 more source
Uptake of pyrimidines and their derivatives into Candida glabrata and Candida albicans [PDF]
The uptake of pyrimidines and their derivatives into Candida glabrata and Candida albicans was measured using a novel technique in which the cells were rapidly separated from their suspending medium by centrifugation through a layer of an inert oil. The uptake of [14C]cytosine was linear for 30 s for all concentrations of pyrimidine tested.
M O, Fasoli, D, Kerridge
openaire +2 more sources
Functional Characterization of the Small Heat Shock Protein Hsp12p from Candida albicans [PDF]
Hsp12p is considered to be a small heat shock protein and conserved among fungal species. To investigate the expression of this heat shock protein in the fungal pathogen Candida albicans we developed an anti-CaHsp12p antibody.
Mühlschlegel, Fritz A. +16 more
core +1 more source
Molecular Typing of Candida glabrata
The yeast Candida glabrata has emerged, second only to Candida albicans, to be one of the most frequently isolated fungi in clinical specimen from human. Its frequent resistance towards azole antifungal drugs and the high capacity to form biofilms on indwelling catheters of individual isolates render it an often difficult to treat pathogen.
Toni Gabaldón +2 more
openaire +3 more sources
Mechanisms of azole resistance in clinical isolates of Candida glabrata collected during a hospital survey of antifungal resistance. [PDF]
The increasing use of azole antifungals for the treatment of mucosal and systemic Candida glabrata infections has resulted in the selection and/or emergence of resistant strains.
Fadda G. +5 more
core +1 more source
Unexpected effects of azole transporter inhibitors on antifungal susceptibility in Candida glabrata and other pathogenic Candida species. [PDF]
The pathogenic fungus Candida glabrata is often resistant to azole antifungal agents. Drug efflux through azole transporters, such as Cdr1 and Cdr2, is a key mechanism of azole resistance and these genes are under the control of the transcription factor ...
Yohsuke Nagayoshi +11 more
doaj +1 more source

