Results 31 to 40 of about 149,523 (218)

A Synthetic β‐Mannan Epitope Enables Immunization and Detection of Candida auris

Angewandte Chemie, EarlyView.
A synthetic β‐mannan epitope enables both active and passive immunization against Candida auris. Conjugation to the carrier protein CRM197 induces protective antibody responses, while monoclonal antibodies targeting the same epitope support detection using a lateral flow assay, linking glycochemistry with antifungal prevention and diagnostics ...
Emelie E. Reuber, Arnab Pradhan, Ian Leaves, Rajat K. Singh, Emer Hickey, Carola Geiler, Neil A. R. Gow, Alistair J. P. Brown, Peter H. Seeberger   +8 more
wiley   +2 more sources

A purine permease inCandida glabrata [PDF]

FEMS Microbiology Letters, 1995
Competition experiments revealed that adenine and guanine were transported by a purine permease in both Candida glabrata 4 and a C. glabrata 4 cytosine permease negative mutant. The C. glabrata 4 cytosine permease negative mutant was isolated using 5-fluorocytosine selection.
S, Sen Gupta, D, Kerridge, M R, Chevallier   +2 more
openaire   +3 more sources

Rapid identification of Candida glabrata in Candida bloodstream infections [PDF]

Journal of Medical Microbiology, 2007
Candida species are the fourth most common cause of bloodstream infection (BSI) in the hospitalized patient. Candida glabrata is the most common non-Candida albicans Candida species in England and Wales with an attributed mortality of 48 %. C.
Nicholas, Foster, Charlotte, Symes, Richard, Barton, Richard, Hobson   +3 more
openaire   +2 more sources

Antifungal activity of the non cytotoxic human peptide hepcidin 20 against fluconazole resistant Candida glabrata in human vaginal fluid [PDF]

, 2013
Vaginal infections due to Candida glabrata are difficult to eradicate, due to the scarce susceptibility to azoles of this species. Previous studies have shown that the human cationic peptide hepcidin 20 (Hep-20) exerts fungicidal activity in sodium ...
Semih Esin, ESIN, SEMIH, LOMBARDI, LISA, Lisa Lombardi, MAISETTA, GIUSEPPANTONIO, Giovanna Batoni, M. Sanguinetti, Giuseppantonio Maisetta, Sanguinetti, Maurizio, Arianna Tavanti, Gaetano Del Gaudio, Maurizio Sanguinetti, Sonia Senesi, SENESI, SONIA, DEL GAUDIO, GAETANO, BATONI, GIOVANNA, TAVANTI, ARIANNA   +16 more
core   +1 more source

Candida glabrata Has No Enhancing Role in the Pathogenesis of Candida-Associated Denture Stomatitis in a Rat Model

mSphere, 2019
Denture stomatitis (DS) is a condition characterized by inflammation of the oral mucosa in direct contact with dentures and affects a significant number of otherwise healthy denture wearers.
Junko Yano, Alika Yu, Paul L. Fidel, Mairi C. Noverr   +3 more
doaj   +1 more source

Uptake of pyrimidines and their derivatives into Candida glabrata and Candida albicans [PDF]

Journal of General Microbiology, 1990
The uptake of pyrimidines and their derivatives into Candida glabrata and Candida albicans was measured using a novel technique in which the cells were rapidly separated from their suspending medium by centrifugation through a layer of an inert oil. The uptake of [14C]cytosine was linear for 30 s for all concentrations of pyrimidine tested.
M O, Fasoli, D, Kerridge
openaire   +2 more sources

Effects of cationic antimicrobial peptides on Candida and Saccharomyces species [PDF]

, 2010
Electronic version does not contain associated previously published materialAntimicrobial peptides (AMPs) are found throughout the animal kingdom and act as a natural defence against a broad spectrum of pathogens.
Harris, Mark R.
core   +2 more sources

Genetic Transformation of Candida glabrata by Electroporation [PDF]

BIO-PROTOCOL, 2015
Here, we report a method for the transformation by electroporation of the human fungal pathogen Candida glabrata (C. glabrata). The protocol can be used for transformations in single well or in 96-well microtiter plates. It has been extensively used to generate a genome-scale gene deletion library using the C.
Fabian Istel, Tobias Schwarzm�ller, Michael Tscherner, Karl Kuchler   +3 more
openaire   +3 more sources

Unexpected effects of azole transporter inhibitors on antifungal susceptibility in Candida glabrata and other pathogenic Candida species. [PDF]

PLoS ONE, 2017
The pathogenic fungus Candida glabrata is often resistant to azole antifungal agents. Drug efflux through azole transporters, such as Cdr1 and Cdr2, is a key mechanism of azole resistance and these genes are under the control of the transcription factor ...
Yohsuke Nagayoshi, Taiga Miyazaki, Shintaro Shimamura, Hironobu Nakayama, Asuka Minematsu, Shunsuke Yamauchi, Takahiro Takazono, Shigeki Nakamura, Katsunori Yanagihara, Shigeru Kohno, Hiroshi Mukae, Koichi Izumikawa   +11 more
doaj   +1 more source

Phenotypic switching and filamentation in Candida glabrata [PDF]

Microbiology, 2002
Candida glabrata switches spontaneously, reversibly and at high frequency among the following four phenotypes distinguishable by graded colony colouration on CuSO(4)-containing agar: white (Wh), light brown (LB), dark brown (DB) and very dark brown (vDB). These phenotypes also differ in a graded fashion in the level of expression of the metallothionein
Salil A, Lachke, Sophie, Joly, Karla, Daniels, David R, Soll   +3 more
openaire   +2 more sources