Results 11 to 20 of about 34,940 (229)

Invasive Candida parapsilosis Bloodstream Infections in Children: The Antifungal Susceptibility, Clinical Characteristics and Impacts on Outcomes

Microorganisms, 2023
Background: Candida parapsilosis is the most common non-albicans candida species that causes invasive candidiasis, but little is known about its impacts on the outcomes of pediatric patients.
Yao-Sheng Wang, Jen-Fu Hsu, Wei-Ju Lee, Shao-Hung Wang, Shih-Ming Chu, Hsuan-Rong Huang, Peng-Hong Yang, Ren-Huei Fu, Ming-Horng Tsai   +8 more
doaj   +1 more source

Signaling through Syk or CARD9 Mediates Species-Specific Anti-Candida Protection in Bone Marrow Chimeric Mice

mBio, 2021
The spleen tyrosine kinase (Syk) and the downstream adaptor protein CARD9 are crucial signaling molecules in antimicrobial immunity. Candida parapsilosis is an emerging fungal pathogen with a high incidence in neonates, while Candida albicans is the most
Erik Zajta, Katalin Csonka, Adél Tóth, Laszló Tiszlavicz, Tamás Németh, Anita Orosz, Ádám Novák, Máté Csikós, Csaba Vágvölgyi, Attila Mócsai, Attila Gácser   +10 more
doaj   +1 more source

Paradigm Shift: Candida parapsilosis sensu stricto as the Most Prevalent Candida Species Isolated from Bloodstream Infections with Increasing Azole-Non-Susceptibility Rates: Trends from 2015–2022 Survey

Journal of Fungi, 2023
Candidemia is the fourth most common healthcare-related bloodstream infection. In recent years, incidence rates of Candida parapsilosis have been on the rise, with differences in prevalence and antifungal susceptibility between countries.
Iacopo Franconi, Cosmeri Rizzato, Arianna Tavanti, Marco Falcone, Antonella Lupetti   +4 more
doaj   +1 more source

Dependence on Mincle and Dectin-2 Varies With Multiple Candida Species During Systemic Infection

Frontiers in Microbiology, 2021
More than 95% of invasive Candida infections are caused by four Candida spp. (C. albicans, C. glabrata, C. tropicalis, C. parapsilosis). C-type lectin-like receptors (CLRs), such as Dectin-1, Dectin-2, and Mincle mediate immune responses to C.
Aiysha Thompson, Aiysha Thompson, Diogo M. da Fonseca, Diogo M. da Fonseca, Louise Walker, James S. Griffiths, James S. Griffiths, Philip R. Taylor, Philip R. Taylor, Neil A. R. Gow, Neil A. R. Gow, Selinda J. Orr, Selinda J. Orr   +12 more
doaj   +1 more source

Candida parapsilosis culture extracts: in vitro, antagonistic action against Candida albicans, Candida auris and Candida parapsilosis

Brazilian Journal of Case Reports, 2022
Fungal infections caused by Candida species has increased significantly in recent years. Additionally, resistance to conventional therapy is an aggravating factor causing high morbidity and mortality, especially in immunocompromised patients or those undergoing treatment with another antimicrobials.
Thiago Henrique Lemes, Julyanna Andrade Silva Nascentes, Luis Octávio Regasini, Taiza Maschio-Lima, Bianca Gottardo De Almeida, Mariela Domiciano Ribeiro, Veridianna Camilo Pattini, Leticia de Queiroz Mozaner, João Paulo Zen Siqueira, Margarete Teresa Gottardo De Almeida   +9 more
openaire   +1 more source

Ultrastructure of Candida parapsilosis endocarditis [PDF]

Infection and Immunity, 1984
We used light microscopy and scanning and transmission electron microscopy to study the structure of Candida parapsilosis vegetations on five surgically removed porcine bioprosthetic valves. Scanning electron microscopy revealed a "mossy" amorphous surface. In some areas, C. parapsilosis cells could be seen below the surface layer.
T J, Marrie, J H, Cooper, J W, Costerton
openaire   +2 more sources

Degradation of human kininogens with the release of kinin peptides by extracellular proteinases of Candida spp. [PDF]

, 2010
The secretion of proteolytic enzymes by pathogenic microorganisms is one of the most successful strategies used by pathogens to colonize and infect the host organism.
Ben Nasr A., Ben Nasr A., Bergmann S., Boskey E.R., Colman R.W., De Bernardis F., Frick I.M., Imamura T., Kaminishi H., Karkowska-Kuleta J., Koelsch G., Maeda H., Maruo K., Matsudaira P., Molla A., Tapper H., White T.C.   +16 more
core   +1 more source

Postantifungal Effect of Micafungin against the Species Complexes of Candida albicans and Candida parapsilosis. [PDF]

PLoS ONE, 2015
Micafungin is an effective antifungal agent useful for the therapy of invasive candidiasis. Candida albicans is the most common cause of invasive candidiasis; however, infections due to non-C.
Sandra Gil-Alonso, Nerea Jauregizar, Elena Eraso, Guillermo Quindós   +3 more
doaj   +1 more source

Kinetic studies of Candida parapsilosis phagocytosis by macrophages and detection of intracellular survival mechanisms [PDF]

, 2014
Peer reviewedPublisher ...
Alonso, Maria F, Bain, Judith M, Erwig, Lars Peter, Gácser, Attila, Jankovics, Ferenc, Papp, Csaba, Tóth, Adél, Tóth, Renáta, Vágvölgyi, Csaba   +8 more
core   +4 more sources

Combination antifungal therapy for treatment of Candida parapsilosis prosthetic valve endocarditis and utility of T2Candida Panel®: A case series

IDCases, 2019
Although Candida species are common pathogens for nosocomial infections, Candida endocarditis is still considered a rare entity. Here, we report two cases of Candida parapsilosis endovascular infections in patients with prosthetic valves, both of which ...
Tania Ahuja, Karen Fong, Eddie Louie
doaj   +1 more source