Results 251 to 260 of about 1,393,284 (302)

Candidate Genes for Insulin Resistance

Diabetes Care, 1996
Insulin resistance confers increased susceptibility to NIDDM, atherosclerotic cardiovascular disease, ovarian hyperandrogenism, and possibly hypertension. Insulin resistance is largely inherited, in rare cases as a monogenic disorder or more commonly as a complex trait.
D E, Moller, C, Bjørbaek, A, Vidal-Puig
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Candidate Genes for Osteoporosis

American Journal of PharmacoGenomics, 2001
Osteoporosis, which afflicts 10 million Americans, is a complex disease characterized by decreased bone mass, microarchitectural deterioration of bone tissue, and an increase in fracture risk. Family and twin studies have established a genetic contribution to the etiology of osteoporosis.
T, Niu, X, Xu
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SNPing Away at Candidate Genes

Genetic Epidemiology, 2001
We develop regression methodology to identify subsets of single nucleotide polymorphisms (SNPs) within candidate genes related to quantitative traits and apply our methods to the simulated Genetic Analysis Workshop (GAW) 12 data set. In the data set we find 694 SNP loci with minimum allele frequencies of at least 0.01.
M A, Suchard, J N, Bailey, D A, Elashoff, J S, Sinsheimer   +3 more
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Pharmacogenetic Candidate Genes for Melanoma

Pharmacogenomics, 2003
The incidence of melanoma is rising at an alarming rate and has become an important public health concern. If detected early, melanoma carries an excellent prognosis after appropriate surgical resection. Unfortunately, advanced melanoma has a poor prognosis and is notoriously resistant to radiation and chemotherapy.
Christopher, Hull, April, Larson, Sancy, Leachman   +2 more
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Polymorphisms in Candidate Asthma Genes

The American Journal of the Medical Sciences, 2001
The triad of reversible airway obstruction, bronchial hyperresponsiveness, and airway inflammation characterizes asthma. The etiology of asthma is complex and involves the interaction of multiple genetic foci and a variety of environmental factors, such as protein allergens, chemical sensitizers, and viral or bacterial proteins.
U, Nanavaty, A D, Goldstein, S J, Levine
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Candidate genes for behavioural ecology

Trends in Ecology & Evolution, 2005
In spite of millions of years of evolutionary divergence, the conservation of gene function is common across distant lineages. As such, genes that are known to influence behaviour in one organism are likely to influence similar behaviours in other organisms.
Fitzpatrick, M.J., Ben-Sahar, Y., Smid, H.M., Vet, L.E.M., Robinson, G.E., Sokolowski, M.B.   +5 more
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Candidate Genes in Eating Disorders

Current Drug Target -CNS & Neurological Disorders, 2003
Environmental influences, as well as biological and genetic factors influence risk for eating disorders. Family and twin studies have shown that eating disorders are familial and suggest the influence of genetic factors on their etiology. Positive associations have been observed for some candidate genes that have been studied (such as 5HT2A receptor ...
Federica, Tozzi, Cynthia M, Bulik
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POLYMORPHISMS OF CANDIDATE GENES IN ESSENTIAL HYPERTENSION

Clinical and Experimental Pharmacology and Physiology, 1992
SUMMARY1. Family and population studies have reported that blood pressure has a heritability of 30–50%, but simple genetic models do not readily explain the patterns of inheritance of hypertension.2. Restriction fragment length polymorphisms were used to study allele frequencies of a selection of candidate genes that may be important in determining the
West, M. J., Summers, K. M., Huggard, P. R.   +2 more
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Candidate genes turning sour

Journal of Animal Breeding and Genetics, 2010
Lehden pääkirjoitus ; v ; 2011 ...
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Selection of Candidate Genes in Hypertension

2005
Essential hypertension is a common disease with multifactorial etiology affecting up to 10 million individuals in the United Kingdom alone. Current knowledge of the genetic contribution to this trait is restricted to a number of rare variants that produce hypertensive phenotypes in a Mendelian fashion and to genes highlighted by work on blood pressure ...
Charles A, Mein, Mark J, Caulfield, Patricia B, Munroe   +2 more
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