Results 111 to 120 of about 1,234,477 (312)

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

When Winning is the Only Thing:  Pure Strategy Nash Equilibria in a Three-Candidate Spatial Voting Model [PDF]

open access: yes
It is well-known that there are no pure strategy Nash equilibria (PSNE) in the standard three-candidate spatial voting model when candidates maximize their share of the vote.
Richard Chisik, Robert J. Lemke
core  

Astrocyte heterogeneity in brain metastases

open access: yesMolecular Oncology, EarlyView.
Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver   +2 more
wiley   +1 more source

Student Teacher edTPA Panel

open access: yes, 2016
This panel discussion examines the experiences of student teacher candidates who recently completed the edTPA during their student teaching ...
Candidates, Student Teacher
core  

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

open access: yesMolecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard   +8 more
wiley   +1 more source

Picture are state queen and other queen candidates (photograph)

open access: yes, 1958
Picture are state queen and other queen ...

core  

Developing professional relationships between supervisors and doctorial candidates [PDF]

open access: yes, 2000
Theoretical models in the leadership, mentorship and relationship marketing domains study the relationship between partners. These models are integrated in this paper to propose a new approach to the dynamics of professional relationships between ...
Erwee, Ronel, McPhail, Janelle
core  

Pedagogical Transformation of Biology Teacher Candidates: Integration of Computational Thinking into STEM Learning [PDF]

open access: yes
This study analyzed the effectiveness of integrating Computational Thinking (CT)-based STEM learning in prospective biology teachers at PGRI Pontianak University, exploring students' perceptions, attitudes, challenges, and opportunities. This integration
Herditiya, Herditiya, Nawawi, Nawawi
core   +1 more source

The Looks of a Winner: Beauty, Gender and Electoral Success [PDF]

open access: yes
We study the role of beauty in politics. For the first time, focus is put on differences in how women and men evaluate female and male candidates and how different candidate traits relate to success in real and hypothetical elections.
Berggren, Niclas   +2 more
core   +2 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

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