Results 111 to 120 of about 2,949,455 (301)
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Politics and GovernanceResearch has identified an alarming gap in migrants’ descriptive representation across Western European countries with long-standing immigration while showing that not all migrant groups are equally (un)successful in gaining elected office.
Daniela Vintila +3 more
doaj +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Of Candidates and Character [PDF]
We study the characteristics of self-selected candidates in corrupt political systems. Potential candidates differ along two dimensions of unobservable character: public spirit (altruism toward others) and honesty (the disutility suffered when selling ...
B. Douglas Bernheim, Navin Kartik
core
First Impressions, America\u27s Paper and Pre-Primary Black Presidential Candidates: The New York Times Coverage of Rev. Jesse Jackson (1983), Rev. AI Sharpton (2003), and Sen. Barack Obama (2007) Campaign Announcements and Initial Days [PDF]
, 2010 Recent research documents how party rules, election reforms, and the growth of primaries and caucuses have greatly changed the presidential nomination process.
Perry, Ravi
core +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Beware of a Naive Perspective: A Prebuttal to Possible U.S. Supreme Court Rulings in McCutcheon v. Federal Election Commission (Part 2) [PDF]
, 2014 Many believe that U.S. Supreme Court Chief Justice Roberts will provide the swing vote in the court's decision in Shaun McCutcheon v. Federal Election Commission (McCutcheon), a case challenging the constitutionality of caps on the total amount of ...
Adam Crowther, Taylor Lincoln
core
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
On committed citizen-candidates. [PDF]
I study if the equilibria of the citizen-candidate model analyzed in Osborne and Slivinski (1996) are robust to some degree of commitment from candidates.
Maravall Rodríguez, Carlos
core