Results 101 to 110 of about 1,234,477 (312)
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Comparing candidates’ beliefs and exam performance in speaking tests
Language Value, 2019 Author/s Cristina Pérez-Guillot Julia Zabala-Delgado Universitat Politècnica de València, Spain ABSTRACT The development of a language exam is not a linear process but rather a round cycle in which, by using the test, we obtain information ...
lvalue lvalue
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
How Black Candidates Affect Voter Turnout [PDF]
Both Black and White voter turnout increases 2-3 percentage points with each Black Democrat on the ballot. Given the groups' representations in the population, the White response is numerically greater.
Ebonya Washington
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The exoplanet eccentricity distribution from Kepler planet candidates [PDF]
, 2012 The eccentricity distribution of exoplanets is known from radial velocity surveys to be divergent from circular orbits beyond 0.1 au. This is particularly the case for large planets where the radial velocity technique is most sensitive.
Kane, Stephen R. +3 more
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Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Independent Candidates in a Parliamentary Election in India: A Poisson Regression Model
The paper attempts to explain the number of independent candidates in Indian parliamentary election in the year 2004. The statistical models developed are applications and generalizations of Poisson and Negative Binomial distributions.
Bhattacharya, Kaushik
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Changes in Timisoara City Hall After 16 years – The 2012 Local Elections. A Case Study
Sfera Politicii, 2012 Local elections 2012 have found Timisoara in a long lasting situation of political exceptionalism: the mayor in office, coming from an almost dissoluted party was reaching the end of his forth mandate.
Corina Turșie
doaj
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
, 2013 "January 16, 2013."; Discusses which states permit political parties to cross-endorse candidates and how cross-endorsement works in these states, including Connecticut.
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