Results 121 to 130 of about 1,234,477 (312)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

The Hotelling-Downs Model with Runoff Voting [PDF]

open access: yes
We consider the Hotelling-Downs model with n >= 2 oce seeking candidates and runo voting. We show that Nash equilibria in pure strategies always exist and that there are typically multiple equilibria, both convergent (all candidates are located at the ...
Jaideep Roy   +2 more
core  

The Citizen-Candidate Model with Imperfect Policy Control [PDF]

open access: yes, 2012
We examine the two-candidate equilibria of the citizen-candidate model whenthe implemented policy arises from a compromise between the government andan unelected external power.
Aytimur, Emre   +3 more
core  

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Supporting Doctoral Candidates with Dyslexia

open access: yes
Dyslexia is a misunderstood condition that has a significant effect on peoples’ educational outcomes at all levels. There is a gap in the literature on supporting doctoral candidates with dyslexia. This small-scale qualitative study focuses on reflective
Benaton, T.
core  

How do Astronaut Candidate Profiles differ from Airline Pilot Profile

open access: yes, 2011
Sixteen years after the second Europe-wide astronaut selection campaign, the European Space Agency started the third campaign by putting out a call for new astronauts in 2008.
Peter Maschke   +5 more
core   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

The Right Look: Conservative Politicians Look Better and Voters Reward It [PDF]

open access: yes
Political candidates on the right are more beautiful or are seen as more competent than candidates on the left in Australia, Finland, France, and the United States.
Berggren, Niclas   +2 more
core  

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