Results 71 to 80 of about 1,234,477 (312)

Analyzing the process of assessing the mental health of teaching candidates for admission to Farhangian University and providing solutions to improve it [PDF]

open access: yesFaṣlnāmah-i Farhang Mushavirah va Ravān/Darmānī
This study aimed to analyze the current status of the components considered for assessing the mental health of teaching candidates for admission to Farhangian University and to provide solutions for its improvement.
seyed sadegh nabavi
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Three-Candidate Competition When Candidates Have Valence: Stochastic Voting [PDF]

open access: yes
We study the effects of stochastic (probabilistic) voting on equilibrium locations, equilibrium vote shares and comparative statics in a setup with three heterogenous candidates and a single-dimensional issue space.
Kha, Dmitriy, Evrenk, Haldun
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Elemental Abundances Of Solar Sibling Candidates [PDF]

open access: yes, 2014
Dynamical information along with survey data on metallicity and in some cases age have been used recently by some authors to search for candidates of stars that were born in the cluster where the Sun formed.
Ramirez, Ivan   +15 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

[News Clip: Two Candidates]

open access: yes, 1961
Video footage from the WBAP-TV television station in Fort Worth, Texas, to accompany a news story about two liberal candidates, Maury Maverick and Henry Gonzales, vying for the newly-vacant senate seat left by Vice President Lyndon ...
WBAP-TV (Television station : Fort Worth, Tex.)
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Belgian Candidates in Search of a Constituency

open access: yes, 2009
Lieven De Winter, Belgian Candidates in Search of a Constituency, paper presented at the Comparative Candidate Survey workshop on “Candidates in Constituency Campaigns in Comparative Perspective”, Cornell University, Ithaca, October 2-3 ...
Candidates in Constituency Campaigns in Comparative Perspective   +1 more
core  

From the Unitary Patent Package to a Federal EU Patent Law

open access: yesPerspectives on Federalism, 2018
For the last forty years, the European Union has been pursuing the goal of a unified system of patent law, which would make it possible for an invention to be protected, by EU law, throughout the territory of the Member-States, with a single application.
Almeida Juliana   +1 more
doaj   +1 more source

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