Results 71 to 80 of about 1,567,650 (332)

Changes in Timisoara City Hall After 16 years – The 2012 Local Elections. A Case Study

open access: yesSfera Politicii, 2012
Local elections 2012 have found Timisoara in a long lasting situation of political exceptionalism: the mayor in office, coming from an almost dissoluted party was reaching the end of his forth mandate.
Corina Turșie
doaj  

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

"Why Do Political Action Committees Give Money to Candidates? Campaign Contributions, Policy Choices, and Election Outcomes" [PDF]

open access: yes
This paper examines political action committees' motivations for giving campaign contributions to candidates for political office. First, the paper estimates the effect of campaign contributions received by candidates on the outcomes of the 1996 ...
Christopher Magee
core   +2 more sources

INFORMAL ORGANIZATIONS AND THEIR PARTICIPATION IN REGIONAL ELECTIONS AT THE TURN OF THE 1980 - 1990-s

open access: yesГуманитарные и юридические исследования, 2021
Article is devoted to the analysis of activities of the informal organizations in the Stavropol Territory under the conditions of destruction of a monopoly position of CPSU in society.
E. Kalinina
doaj  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

150 new transiting planet candidates from Kepler Q1-Q6 data [PDF]

open access: yes, 2012
We have performed an extensive search for planet candidates in the publicly available Kepler long cadence data from quarters Q1 through Q6. The search method consists of initial detrending of the data, applying the trend filtering algorithm, searching ...
Huang, X   +5 more
core   +1 more source

Diversity in Spanish Politics? Dynamics of Descriptive Representation of Immigrant‐Origin Minorities in Local Elections

open access: yesPolitics and Governance
Research has identified an alarming gap in migrants’ descriptive representation across Western European countries with long-standing immigration while showing that not all migrant groups are equally (un)successful in gaining elected office.
Daniela Vintila   +3 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Intra-party ideological heterogeneity: Are candidates agents of their parties?

open access: yes, 2020
Party cohesion is a necessary condition for parties functioning as a mechanism of democratic accountability. However, if candidates represent a wide range of policy views, the concept of programmatic party representation may be weakened.
Daniela Giannetti, Luca Pinto
core   +1 more source

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