Results 41 to 50 of about 10,840 (135)

Antifungal Activity of Hedychium spicatum Essential Oil Against Candidemia‐Causing Candida tropicalis and Candida parapsilosis: In Vitro Evaluation and Computational Identification of Cis‐γ‐Bisabolene as a Putative CYP51‐Binding Constituent

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Hedychium spicatum essential oil (HSEO) exhibited concentration‐dependent antifungal activity against Candida parapsilosis and Candida tropicalis. GC‐MS identified 29 phytoconstituents, with τ‐cadinol as the major component. Computational analysis identified cis‐γ‐bisabolene as a promising CYP51 inhibitor, showing favorable binding, ADMET properties ...
Preeti Verma, Devesh Singh Baral, Rakesh Verma   +2 more
wiley   +1 more source

Diagnostic efficiency of inflammatory signatures to distinguish isolated candidemia from candidemia with bacterial co-infection

Frontiers in Immunology
IntroductionTo identify the differences in inflammatory response between critically ill patients responding to combined bacterial-fungal sepsis and those with isolated fungal sepsis.MethodsA retrospective case-control study compared ICU patients who were
Magdalena Mnichowska-Polanowska, Bartłomiej Grygorcewicz, Bartłomiej Grygorcewicz, Barbara Dołęgowska, Agnieszka Boroń, Agata Michnowska, Agata Michnowska, Konrad Jarosz, Magdalena Adamowicz, Bartosz Wojciuk   +9 more
doaj   +1 more source

Economic Evaluation of Voriconazole for the Treatment of Candidemia in Canadian Adults

Canadian Journal of Infectious Diseases and Medical Microbiology, 2008
BACKGROUND: Candidemia is a common cause of nosocomial bloodstream infection. When selecting therapeutic treatments for candidemia, cost-effectiveness is an important consideration.
Coleman Rotstein, Lael Cragin, Michel Laverdière, Gary Garber, Eric J Bow, Alissa Scalera, Craig Roberts, Sonja V Sorenson, the Canadian Expert Panel   +8 more
doaj   +1 more source

Trends in the Epidemiology of Candidemia in Intensive Care Units From 2006 to 2017: Results From the Korean National Healthcare-Associated Infections Surveillance System

Frontiers in Medicine, 2020
Candidemia is an important healthcare-associated infection (HAI) in intensive care units (ICUs). However, limited research has been conducted on candidemia in the Republic of Korea. We aimed to analyze the secular trends in the incidence and distribution
Eun Jin Kim, Eunyoung Lee, Eunyoung Lee, Yee Gyung Kwak, Hyeon Mi Yoo, Ji Youn Choi, Sung Ran Kim, Myoung Jin Shin, So-Yeon Yoo, Nan-Hyoung Cho, Young Hwa Choi   +10 more
doaj   +1 more source

A quality improvement initiative to improve the appropriateness of candidemia management by the implementation of a comprehensive candidemia care bundle at a tertiary care hospital in South India

Medicine, 2022
. Management of candidemia in developing countries like India encounters laxity in appropriate clinical management and challenges in terms of healthcare capacity, despite its association with high morbidity and mortality.
Merlin Moni, MD, Neeraj Sidharthan, DM, Sangita Sudhir, Pharm D, Binny Prabhu, MD, Vrinda Nampoothiri, Pharm D, Jini James, Pharm D, Jeslyn Mary Philip, Pharm D, Jisha Thomas, Pharm D, Remya Antony, Pharm D, Zubair Umer Mohamed, MD, Anil Kumar, MD, Preetha Prasanna, MBA, Fabia Edathadathil, MSc, Sanjeev Singh, MD, PhD, Dipu Sathyapalan, MD, Max Carlos Ramírez-Soto   +15 more
doaj   +1 more source

Fungal Antimicrobial Resistance: Mechanisms, Drivers, and Global Clinical Burden

ChemFoodChem, Volume 2, Issue 3, September 2026.
ABSTRACT Fungal antimicrobial resistance (AMR) is a growing concern for world health caused by an increase in multidrug‐resistant infections, an increase in environmental reservoirs, and the ineffectiveness of current antifungal treatments. Fungal infections continue to be largely excluded from AMR initiatives while causing over 1.6 million deaths ...
Bikash Baral
wiley   +1 more source

In Vitro and In Silico Analysis of Antioxidant and Antifungal Activity of Essential Oil From Achillea biebersteinii

ChemPlusChem, Volume 91, Issue 9, September 2026.
Essential oil of Achillea biebersteinii Afan. flowers exhibits moderate antioxidant activity in DPPH• and ABTS+ assays, while it demonstrates high anticandidal activity, with MFC (0.937−3.75 μL/mL) values. α‐Terpineol and trans‐Pinocarveol are antifungal compounds responsible for the effect against both C. glabrata and C.
Zehra Torun, Tuba Unver, M. Abdullah Alagoz   +2 more
wiley   +1 more source

Development of a Gold Nanoparticle‐Assisted Multiplex Polymerase Chain Reaction Assay for Selected Hospital‐Acquired Infections‐Associated Bacterial and Fungal Pathogens

ChemistryOpen, Volume 15, Issue 9, September 2026.
Gold nanoparticle‐assisted multiplex PCR enables the simultaneous detection of six major hospital‐acquired infection‐associated pathogens by improving amplification performance and assay specificity, providing an analytical proof‐of‐concept for rapid molecular identification.
Kubra Aslan, Emre Erden Kopar, Serap Evran   +2 more
wiley   +1 more source

Long‐Term Use of Rezafungin: A Case Report and Insights Into Real‐World Access

Transplant Infectious Disease, EarlyView.
Jian Mei Li, Jacqueline E. Clark, Tiffany Wu   +2 more
wiley   +1 more source

Antifungal Susceptibility Profile and Biocide Tolerance in Clinically Relevant Yeasts: Implications for Therapy and Hospital Infection Control

Mycoses, Volume 69, Issue 9, September 2026.
ABSTRACT Background Opportunistic yeasts account for a substantial proportion of invasive fungal infections and are important agents of healthcare‐associated infections, especially in intensive care units (ICUs). Objectives To describe the clinical and epidemiological characteristics of hospitalized patients with positive cultures for medically ...
Yasmim Passos Lima, Letícia Rebello Machado, Ricardo Villela Bastos, Victor Quinet de Andrade Bastos, Lucas Quinet de Andrade Bastos, André Netto Bastos, Claudio Galuppo Diniz, Vania Lúcia da Silva, Vanessa Cordeiro Dias   +8 more
wiley   +1 more source