Results 71 to 80 of about 30,750 (313)

Nosocomial candidemia; risk factors and prognosis revisited; 11 years experience from a Norwegian secondary hospital. [PDF]

PLoS ONE, 2014
The aim of the study was to review the epidemiology and prognosis of candidemia in a secondary hospital, and to examine the intra-hospital distribution of candidemia patients. Study design is a retrospective cohort study.
Jan-Erik Berdal, Rolf Haagensen, Trond Ranheim, Jørgen V Bjørnholt   +3 more
doaj   +1 more source

Degradation of human kininogens with the release of kinin peptides by extracellular proteinases of Candida spp. [PDF]

, 2010
The secretion of proteolytic enzymes by pathogenic microorganisms is one of the most successful strategies used by pathogens to colonize and infect the host organism.
Ben Nasr A., Ben Nasr A., Bergmann S., Boskey E.R., Colman R.W., De Bernardis F., Frick I.M., Imamura T., Kaminishi H., Karkowska-Kuleta J., Koelsch G., Maeda H., Maruo K., Matsudaira P., Molla A., Tapper H., White T.C.   +16 more
core   +1 more source

Clonal Candidemia Outbreak by Candida parapsilosis Carrying Y132F in Turkey: Evolution of a Persisting Challenge

Frontiers in Cellular and Infection Microbiology, 2021
As the second leading etiological agent of candidemia in Turkey and the cause of severe fluconazole-non-susceptible (FNS) clonal outbreaks, Candida parapsilosis emerged as a major health threat at Ege University Hospital (EUH).
A. Arastehfar, S. Hilmioğlu-Polat, F. Daneshnia, W. Pan, Ahmed Hafez, W. Fang, W. Liao, Zümrüt Şahbudak-Bal, D. Metin, J. N. D. A. Júnior, M. Ilkit, D. Perlin, C. Lass‐Flörl   +12 more
semanticscholar   +1 more source

First Report of Candidemia Clonal Outbreak Caused by Emerging Fluconazole-Resistant Candida parapsilosis Isolates Harboring Y132F and/or Y132F+K143R in Turkey

Antimicrobial Agents and Chemotherapy, 2020
Clonal outbreaks of fluconazole-resistant (FLZR) Candida parapsilosis isolates have been reported in several countries. Despite its being the second leading cause of candidemia, the azole resistance mechanisms and the clonal expansion of FLZR C ...
A. Arastehfar, F. Daneshnia, S. Hilmioğlu-Polat, W. Fang, Melike Yaşar, Furkan Polat, D. Metin, P. Rigole, T. Coenye, M. Ilkit, W. Pan, W. Liao, F. Hagen, M. Kostrzewa, D. Perlin, C. Lass‐Flörl, T. Boekhout   +16 more
semanticscholar   +1 more source

Delta neutrophil index as a predictive and prognostic factor for Candidemia patients: a matched case-control study

BMC Infectious Diseases, 2020
Background Delayed antifungal therapy for candidemia leads to increased mortality. Differentiating bacterial infection from candidemia in systemic inflammatory response syndrome (SIRS) patients is complex and difficult.
So Yeon Park, Jin Seo Lee, Jihyu Oh, Ji-Young Park   +3 more
doaj   +1 more source

Incidence, clinical characteristics, risk factors and outcomes of patients with mixed Candida/bacterial bloodstream infections: a retrospective study

Annals of Clinical Microbiology and Antimicrobials, 2022
Purpose The mixed Candida/bacterial bloodstream infections (mixed C/B-BSIs) is worthy of particular attention recently, and we analyzed the incidence, co-pathogens, clinical characteristics, risk factors, and outcomes of mixed C/B-BSIs compared with ...
Li Zhong, Zhaohui Dong, Fengqi Liu, Haidong Li, Kankai Tang, Cheng Zheng, Lifang Wang, Kai Zhang, Jiachang Cai, Hongwei Zhou, Wei Cui, Yanqiu Gao, Gensheng Zhang   +12 more
doaj   +1 more source

A complete clinico-epidemiological and microbiological profile of candidemia cases in a tertiary-care hospital in Western India

Antimicrobial Stewardship and Healthcare Epidemiology, 2022
Objective: To identify different Candida spp along with antifungal susceptibility pattern and risk factors associated with candidemia. Design, setting, and patients: This retrospective observational study was conducted in a tertiary-care academic ...
E. Rajni, P. Chaudhary, V. Garg, Rajani Sharma, Manisha Malik   +4 more
semanticscholar   +1 more source

Candidemia due to uncommon Candida species in children: new threat and impacts on outcomes

Scientific Reports, 2018
Many uncommon Candida spp. (species other than C. albicans, C. parapsilosis, C. glabrata, C. tropicalis, and C. krusei) have been shown to emerge in tertiary care facilities. We aimed to investigate these uncommon candidemia in children.
Ming-Horng Tsai, Jen-Fu Hsu, Lan-Yan Yang, Yu-Bin Pan, Mei-Yin Lai, Shih-Ming Chu, Hsuan-Rong Huang, Ming-Chou Chiang, Ren-Huei Fu, Jang-Jih Lu   +9 more
doaj   +1 more source

Epidemiology and risk factors of candidemia due to Candida parapsilosis in an intensive care unit

Revista do Instituto de Medicina Tropical de São Paulo, 2021
We analyzed the clinical features and risk factors of candidemia due to C. parapsilosis (n=104) in the intensive care unit of a tertiary hospital over six years.
Xiao-shu Zuo, Yanan Liu, Ke Hu
doaj   +1 more source

Outcomes by Candida spp. in the ReSTORE Phase 3 trial of rezafungin versus caspofungin for candidemia and/or invasive candidiasis

Antimicrobial Agents and Chemotherapy
Rezafungin is a long-acting, intravenously administered echinocandin for the treatment of candidemia and invasive candidiasis (IC). Non-inferiority of rezafungin vs caspofungin for the treatment of adults with candidemia and/or IC was demonstrated in the
J. B. Locke, C. Pillar, M. Castanheira, C. Carvalhaes, David R. Andes, J. Aram, Christina Andrzejewski, Ken Bartizal, Anita F Das, T. Sandison, George R Thompson, Peter G. Pappas   +11 more
semanticscholar   +1 more source