Results 71 to 80 of about 23,500 (271)
Invasive candidiasis as a cause of sepsis in the critically ill patient. [PDF]
Invasive fungal infections are an increasingly frequent etiology of sepsis in critically ill patients causing substantial morbidity and mortality. Candida species are by far the predominant agent of fungal sepsis accounting for 10% to 15% of health-care ...
Calandra, T., Delaloye, J.
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In this issue, the article “Candida glabrata candidemia: An emerging threat in critically ill patients” demands discussion on this topic as C. glabrata candidemia is difficult to manage and the patients have high mortality. Clinicians, epidemiologists, microbiologists, and basic scientists across the world are working on the epidemiology, pathogenesis,
openaire +2 more sources
ABSTRACT Introduction Studies evaluating the incidence of infections after belatacept as a substitute for calcineurin inhibitors (CNI) or antimetabolite in kidney transplant (KT) yielded conflicting results. We compared infectious outcomes after belatacept‐use to no belatacept‐use in KT recipients.
Hareesh Singam +5 more
wiley +1 more source
Occurrence of yeast bloodstream infections between 1987 and 1995 in five Dutch university hospitals [PDF]
The aim of this study was to identify retrospectively trends in fungal bloodstream infections in The Netherlands in the period from 1987 to 1995. Results of over 395,000 blood cultures from five Dutch university hospitals were evaluated.
Hoogkamp-Korstanje, J.A.A. (J. A A) +9 more
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Persistent systemic microbial translocation, inflammation, and intestinal damage during Clostridioides difficile infection [PDF]
Background. Clostridioides difficile infection (CDI) might be complicated by the development of nosocomial bloodstream infection (n-BSI). Based on the hypothesis that alteration of the normal gut integrity is present during CDI, we evaluated markers of ...
Aversano, L. +13 more
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Patients with invasive fungal infections still have high morbidity and mortality despite an increasing number of antifungals and other therapies. Because of this problem, an accurate and rapid diagnosis is mandatory in order to improve clinical outcome in these patients. In this paper we review the tools for the diagnosis of candidemia, including blood
Vitale, Roxana Gabriela, Nucci, Marcio
openaire +2 more sources
The role of T cells in sepsis of distinct infectious aetiologies
Pathogen‐specific sepsis induces mitochondrial dysfunction in T cells, leading to functional alterations. Single‐cell transcriptomics reveals subtype‐specific impairments involving reactive oxygen species accumulation, mtDNA damage, calcium dysregulation, and metabolic reprogramming.
Xuanqi Liu +5 more
wiley +1 more source
Quantitative Analysis of Candida Cell Wall Components by Flow Cytometrywith Triple-Fluorescence Staining [PDF]
This work was supported by the European Commission within the FP7 Framework Programme [Fungitect-Grant No 602125]. We also thank Thomas Sauer, Vienna Biocenter Campus (VBC), Austria, for technical support at the FACS facility of the MFPL, Karl Kuchler ...
Gow, N +5 more
core +1 more source
C. anisata fruit extract and its compounds demonstrated potent broad‐spectrum antimicrobial activity, notably against Klebsiella pneumoniae (MIC 0.625 mg/mL; MLC 2.5 mg/mL) and Candida albicans (MIC 0.0781 mg/mL; MLC 0.625 mg/mL). The findings highlight promising bactericidal and fungicidal potential of stigmasteryl 3‐palmitate and phellopterin against
Emmanuel Kofi Kumatia +5 more
wiley +1 more source
Background Candidemia is the worldwide life-threaten disease, especially in cancer patients. This study was aimed to identify and evaluate the risk factors of candidemia in cancer patients, which will prompt the improvement on current therapeutic ...
Ding Li +5 more
doaj +1 more source

