Results 81 to 90 of about 13,407 (217)
The role of T cells in sepsis of distinct infectious aetiologies
Pathogen‐specific sepsis induces mitochondrial dysfunction in T cells, leading to functional alterations. Single‐cell transcriptomics reveals subtype‐specific impairments involving reactive oxygen species accumulation, mtDNA damage, calcium dysregulation, and metabolic reprogramming.
Xuanqi Liu +5 more
wiley +1 more source
BackgroundThe incidence of nosocomial candidemia has increased in recently years, however, the epidemiological data remain insufficient in China.MethodsA total of 234 candidemia patients were included from Xiamen University Zhong Shan hospital between ...
Zhang Dai +11 more
doaj +1 more source
ABSTRACT Background and Aims Catheter‐associated bloodstream infections (CABSI) cause a significant clinical and financial burden in nephrology. This study aimed to identify the clinical risk factors and prevalent pathogens associated with CABSI among hemodialysis (HD) patients at a tertiary care hospital in Pakistan. Methods This cross‐sectional study
Muhammad Shaheer Bin Faheem +6 more
wiley +1 more source
C. anisata fruit extract and its compounds demonstrated potent broad‐spectrum antimicrobial activity, notably against Klebsiella pneumoniae (MIC 0.625 mg/mL; MLC 2.5 mg/mL) and Candida albicans (MIC 0.0781 mg/mL; MLC 0.625 mg/mL). The findings highlight promising bactericidal and fungicidal potential of stigmasteryl 3‐palmitate and phellopterin against
Emmanuel Kofi Kumatia +5 more
wiley +1 more source
Background We evaluated the epidemiology, clinical characteristics, microbiology, outcomes, and risk factors for mortality of candidemia in adult surgical patients in Shenyang from 2012 to 2018.
Wei Zhang +3 more
doaj +1 more source
A clinicopathological study of candidemia in the elderly.
Candidemias were reviewed in 22 elderly patients hospitalized in Yokufukai Geriatric Hospital. Their ages ranged from 62 to 101 years, with a mean age of 81 years. Sixteen patients had either old cerebrovascular disease or senile dementia. In seven patients, synchronous or metachronous bacteremia in the blood culture was associated with the candidemia.
Kawahata, Nobuya +2 more
openaire +3 more sources
Bloodstream infections (BSI) are one of the leading causes of mortality and morbidity in both civilian and military populations. This paper summarizes recent progress in novel treatment strategies to manage BSI arising from both bacterial and fungal pathogens using molecules, particles, and materials to elicit host‐directed immunity.
Thomas Thomou +11 more
wiley +1 more source
This paper describes the isolation and antifungal activity of secondary metabolites from the leaves and roots of Monotes kerstingii. The distribution of these metabolites in the roots and leaves was achieved through comprehensive RP‐UHPLC‐Orbitrap‐MS and MS/MS analysis.
Sorelle Kache Fotsing +12 more
wiley +1 more source
Cancer patients are at a high risk of Candida infections, and candidemia may aggravate the prognosis among patients with cancers. To investigate the incidence, mortality, risk factors, and antifungal resistance of candidemia among cancer patients, 100 ...
Limei Chen +8 more
doaj +1 more source
A case of 1-year- old male multivisceral transplant recipient with candidemia diagnosed by the T2Candida® test is presented. Optimal management of the candidemia complemented the treatment of the global clinical episode.
Iker Falces-Romero +8 more
doaj +1 more source

