Results 71 to 80 of about 14,635 (217)

Development of a Gold Nanoparticle‐Assisted Multiplex Polymerase Chain Reaction Assay for Selected Hospital‐Acquired Infections‐Associated Bacterial and Fungal Pathogens

ChemistryOpen, Volume 15, Issue 9, September 2026.
Gold nanoparticle‐assisted multiplex PCR enables the simultaneous detection of six major hospital‐acquired infection‐associated pathogens by improving amplification performance and assay specificity, providing an analytical proof‐of‐concept for rapid molecular identification.
Kubra Aslan, Emre Erden Kopar, Serap Evran   +2 more
wiley   +1 more source

Antifungal Susceptibility Profile and Biocide Tolerance in Clinically Relevant Yeasts: Implications for Therapy and Hospital Infection Control

Mycoses, Volume 69, Issue 9, September 2026.
ABSTRACT Background Opportunistic yeasts account for a substantial proportion of invasive fungal infections and are important agents of healthcare‐associated infections, especially in intensive care units (ICUs). Objectives To describe the clinical and epidemiological characteristics of hospitalized patients with positive cultures for medically ...
Yasmim Passos Lima, Letícia Rebello Machado, Ricardo Villela Bastos, Victor Quinet de Andrade Bastos, Lucas Quinet de Andrade Bastos, André Netto Bastos, Claudio Galuppo Diniz, Vania Lúcia da Silva, Vanessa Cordeiro Dias   +8 more
wiley   +1 more source

Economic Evaluation of Voriconazole for the Treatment of Candidemia in Canadian Adults

Canadian Journal of Infectious Diseases and Medical Microbiology, 2008
BACKGROUND: Candidemia is a common cause of nosocomial bloodstream infection. When selecting therapeutic treatments for candidemia, cost-effectiveness is an important consideration.
Coleman Rotstein, Lael Cragin, Michel Laverdière, Gary Garber, Eric J Bow, Alissa Scalera, Craig Roberts, Sonja V Sorenson, the Canadian Expert Panel   +8 more
doaj   +1 more source

Candida glabrata candidemia

Indian Journal of Critical Care Medicine, 2015
In this issue, the article “Candida glabrata candidemia: An emerging threat in critically ill patients” demands discussion on this topic as C. glabrata candidemia is difficult to manage and the patients have high mortality. Clinicians, epidemiologists, microbiologists, and basic scientists across the world are working on the epidemiology, pathogenesis,
openaire   +2 more sources

Genotypes, Fluconazole Tolerance and Virulence Phenotypes of Candida albicans Bloodstream Isolates: A Multilocus Sequence Typing‐Based Analysis

Mycoses, Volume 69, Issue 9, September 2026.
ABSTRACT Background Fluconazole tolerance is an emerging phenotype in Candida albicans bloodstream infections, but its relationship to multilocus sequence typing (MLST) lineages and virulence traits is unclear. Objectives To investigate the relationships among MLST genotypes, fluconazole tolerance, and virulence phenotypes in C.
Shang‐Yi Lin, Yin‐Tse Huang, Ho‐Yin Huang, Wei‐Chun Hung, Yi‐Ting Tseng, Po‐Liang Lu   +5 more
wiley   +1 more source

A low serum uric acid concentration predicts a poor prognosis in adult patients with candidemia

Open Medicine, 2022
This study aimed to determine the relation of serum uric acid (UA) level with outcomes in adults with candidemia. Medical records of patients with candidemia treated from 2014 to 2017 were retrospectively reviewed. Patients were age- and sex-matched with
Zhou Yuqi, Li Wenjuan, Huang Yubo
doaj   +1 more source

Neonatal Bloodstream Infections: A Narrative Review on Diagnostic and Therapeutic Challenges and Prospects in Developing Countries

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Bloodstream infections (BSIs) pose a significant global health challenge, particularly in developing countries. Neonates are highly vulnerable due to underdeveloped immune systems and immature physical barriers, a risk amplified by poor hygiene and limited healthcare access in low‐ and middle‐income countries (LMICs), leading to an ...
Alex Odoom, Abdul‐Halim Osman, Onyansaniba K. Ntim, Fleischer C. N. Kotey, Eric S. Donkor   +4 more
wiley   +1 more source

Treatment of candidemia caused by Candida albicans and Candida non - albicans in patients with hematological malignancies [PDF]

Терапевтический архив, 2019
Aim. To study the risk factors, symptoms and outcomes of candidemia caused by C. albicans and C. non - albicans in patients with hematological malignancies. Materials and methods. The study included patients with hematological malignancies and candidemia.
G A Klyasova, A O Malchikova, K S Tandilova, E V Blohina, E N Parovichnikova, S K Kravchenko, V G Savchenko   +6 more
doaj   +1 more source

Effects of the HDAC6/8 Inhibitor MC1568, Alone and in Combination With Fluconazole, in Non‐Albicans Candida Species Infections

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
This study explores new antifungal strategies to combat non‐albicans Candida species. We tested clinically approved HDAC inhibitors—Vorinostat, Romidepsin, Tucidinostat—and the HDAC6/8‐selective MC1568, alone and with Fluconazole. The Fluconazole/MC1568 combination significantly enhanced antifungal activity and reduced biofilm formation.
Andrea Giammarino, Chiara Lambona, Alessia Raucci, Giovanna Simonetti, Salvatore Macrì, Angela Iuzzolino, Daniela Trisciuoglio, Sergio Valente, Gustavo Giusiano, Letizia Angiolella, Antonello Mai   +10 more
wiley   +1 more source

Diagnostic efficiency of inflammatory signatures to distinguish isolated candidemia from candidemia with bacterial co-infection

Frontiers in Immunology
IntroductionTo identify the differences in inflammatory response between critically ill patients responding to combined bacterial-fungal sepsis and those with isolated fungal sepsis.MethodsA retrospective case-control study compared ICU patients who were
Magdalena Mnichowska-Polanowska, Bartłomiej Grygorcewicz, Bartłomiej Grygorcewicz, Barbara Dołęgowska, Agnieszka Boroń, Agata Michnowska, Agata Michnowska, Konrad Jarosz, Magdalena Adamowicz, Bartosz Wojciuk   +9 more
doaj   +1 more source