Complete Genome Characterization of Canine Adenovirus From Türkiye With Next‐Generation Sequencing
Background Determining the complete genome sequence data of adenoviruses has recently become greatly important due to their use by scientists as vectors in cancer studies and other fields, including vaccine development.
Secil Sevinc Temizkan +1 more
doaj +1 more source
Bovine babesiosis is an important disease of cattle where Rhipicephalus microplus acts as a vector for the two causal organisms Babesia bovis and Babesia bigemina.
Ana Paula Silva +4 more
doaj +1 more source
Development of one-step multiplex real-time PCR for the detection of CHV-1, CAdV-2, and CDV
Canine Infectious Respiratory Disease Complex (CIRDC) is a highly contagious disease that frequently affects canine populations and has emerged as a global epidemic. It has been reported that CIRDC can have a serious impact on related life.
Yifan Li +8 more
doaj +1 more source
Molecular Detection of Viral and Bacterial Pathogens in Red Foxes (Vulpes vulpes) from Italy
Animals, including wildlife, are part of One-Health concept since many infectious diseases can affect both humans and animals. In this study, 126 red foxes (Vulpes vulpes) from Northern Italy in 2022–2023 were tested by molecular assays for ...
Martina Magliocca +12 more
doaj +1 more source
Studies of the adenovirus 5 L1 gene aimed at developing L1 gene deficiencies for use in gene therapy vectors [PDF]
Gene therapy is a novel approach to the treatment of human disease that is in its very early stages of development. Its purpose is to add to and/or alter the pattern of gene expression in cells so as to achieve a therapeutic benefit and is being ...
Arslanoglu, Alper
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Antibody titer testing can be useful in controlling successful puppy immunization and can reduce unnecessary vaccinations in adult dogs. We evaluated three commercially available point-of-care tests (POCTs) for detecting antibodies against canine ...
Lena Janowitz +4 more
doaj +1 more source
CAV-2 Vector Development and Gene Transfer in the Central and Peripheral Nervous Systems
The options available for genetic modification of cells of the central nervous system (CNS) have greatly increased in the last decade. The current panoply of viral and nonviral vectors provides multifunctional platforms to deliver expression cassettes to
Danila del Rio +7 more
doaj +1 more source
Carrier cell-mediated cell lysis of squamous cell carcinoma by squamous cell carcinoma antigen 1 promoter-driven oncolytic adenovirus [PDF]
The squamous cell carcinoma antigen (SCCA) serves as a serological marker for squamous cell carcinomas. Molecular cloning of the SCCA genomic region has revealed the presence of two tandemly arrayed genes, SCCA1 and SCCA2.
Yoshiyuki Koyama +7 more
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Canine Infectious Respiratory Disease Complex (CIRDC), caused by a diverse range of viral and bacterial pathogens, is the leading cause of respiratory illness in dogs.
Côme J. Thieulent +7 more
doaj +1 more source
Lipopolysaccharide is a frequent contaminant of plasmid DNA preparations and can be toxic to primary cells in the presence of adenovirus [PDF]
Endotoxin (lipopolysaccharide, LPS) is commonly found as a contaminant in plasmid DNA preparations. We demonstrate here that the quantities of LPS typically contaminating DNA preparations can generate a toxicity to primary cells (primary human skin ...
Cotten, M. +7 more
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