Results 41 to 50 of about 608 (157)

Investigation of canine chaphamaparvovirus, canine bufavirus, and canine adenovirus in dogs with diarrhea: First report of novel canine bufavirus in Turkey

open access: yes, 2023
Viral enteritis is a significant cause of death among dogs younger than 6 months. In this study, the presence of canine chaphamaparvovirus (CaChPV), canine bufavirus (CBuV), and canine adenovirus (CAdV) was investigated in 62 diarrheal dogs previously ...
Tumer, Kenan Cagri   +10 more
core   +1 more source

An Oil-Based Adjuvant Improves Immune Responses Induced by Canine Adenovirus-Vectored Vaccine in Mice

open access: yesViruses, 2023
There is a significant need for highly effective vaccines against emerging and common veterinary infectious diseases. Canine adenovirus type 2 (CAV2) vectors allow rapid development of multiple vaccines and have demonstrated their potential in animal ...
Manon Broutin   +5 more
doaj   +1 more source

Ca2+‐Activated Cl− Channels: Do Bestrophins and TMEM16A Interact?

open access: yesActa Physiologica, Volume 242, Issue 6, June 2026.
ABSTRACT Aim Ca2+‐activated Cl– conductances are present in many cell types and are important for regulating membrane potential as well as other cellular functions. TMEM16A is widely accepted as the principal molecular basis for Ca2+‐activated Cl– conductances, but also members of the bestrophin family may be important for some Ca2+‐activated Cl ...
Christian Aalkjær   +4 more
wiley   +1 more source

Adenovirus-based gene therapy approaches for hemophilia B [PDF]

open access: yes, 2012
Gene therapy can be used to treat devastating inherited diseases, especially diseases and patients that are not suitable for a conventional cure. The blood clotting disorder hemophilia is one of the most extensively studied monogenetic diseases in gene ...
Zhang, Wenli
core  

Emerging Roles of Adenosine Metabolism in Astrocytes During Brain Injury

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 5, May 2026.
Adenosine, as a key metabolic and neurotransmitter in the brain, has become an important therapeutic target for improving the efficacy of immunotherapy for stroke. However, gaps in knowledge about its metabolic pathways have become a key factor limiting its clinical translation.
Shu Zhu   +4 more
wiley   +1 more source

Advances in Gene Therapy for Xerostomia: Current Perspectives and Future Directions: A Narrative Review

open access: yesHealth Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Xerostomia, or dry mouth, significantly impairs quality of life and oral health, particularly in patients subjected to radiation therapy or suffering from systemic disorders. This narrative review summarizes the current evidence on the efficacy and safety of gene therapy interventions for xerostomia, exploring innovative ...
Muhammad Usman Bilal   +6 more
wiley   +1 more source

Molecular evidence for vaccine-induced canine distemper virus and canine adenovirus 2 coinfection in a fennec fox

open access: yesJournal of Veterinary Diagnostic Investigation, 2020
A 61-d-old fennec fox ( Vulpes zerda), 11 d after receiving a multivalent, modified-live virus vaccine containing canine distemper virus (CDV), canine adenovirus 2 (CAdV-2), parainfluenza virus, parvovirus, and canine coronavirus, developed oculonasal discharge, and subsequently convulsions, and hemoptysis, and died. Microscopic changes in the cerebrum
Kenichi Tamukai   +6 more
openaire   +3 more sources

Integrated Use of Molecular Techniques to Detect and Genetically Characterise DNA Viruses in Italian Wolves (Canis lupus italicus)

open access: yesAnimals, 2021
In this study, internal organs (tongue, intestine, and spleen) of 23 free-ranging Italian wolves (Canis lupus italicus) found dead between 2017 and 2019 were tested for Carnivore protoparvovirus 1, Canine adenovirus (CAdV), and Canine circovirus ...
Andrea Balboni   +9 more
doaj   +1 more source

A Case of Sepsis Caused by ST80 Multidrug‐Resistant Enterococcus faecium With Concurrent Klebsiella pneumoniae Infection in a Dog

open access: yesVeterinary Medicine and Science, Volume 12, Issue 3, May 2026.
An 8‐year‐old dog developed acute respiratory distress that progressed to sepsis and death. Multidrug‐resistant Enterococcus faecium ST80 was isolated from the liver and kidney, while Klebsiella pneumoniae was detected in the lung by PCR. Whole‐genome sequencing showed that the ST80 isolates were genetically identical, suggesting hematogenous spread ...
Hyung‐min Seo   +5 more
wiley   +1 more source

Ischaemic dermatopathy associated with multiple vaccinations in a miniature poodle

open access: yesVeterinary Record Case Reports, Volume 14, Issue 2, May 2026.
Abstract A 10‐year‐old, spayed, female miniature poodle presented with hyperpigmented alopecia. Two months prior, it had received two polyvalent vaccines 2 weeks apart. Erythematous alopecia at the injection sites was initially observed. These rapidly expanded to the ventral neck and thoracic regions after further rabies vaccination.
Daekyung Kim   +3 more
wiley   +1 more source

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