Results 91 to 100 of about 148 (128)

Isolation and identification of canine adenovirus type-2 from the upper respiratory tract of a dog

New Zealand Veterinary Journal, 1998
To report on the isolation and identification of canine adenovirus type-2 (CAV-2) from a greyhound dog with tracheitis/tonsillitis.Virus isolation was performed with Madin and Darby canine kidney (MDCK) cell monolayers using standard virological techniques. The isolated virus was identified by haemagglutination inhibition and serum neutralisation tests.
K M Tham, G W Horner
exaly   +3 more sources

Evaluation of a Canine Adenovirus Type 2 Strain as a Replacement for Infectious Canine Hepatitis Vaccine

Journal of the American Veterinary Medical Association, 1980
SUMMARY A modified live strain of canine adenovirus type 2 (CAV-2) was developed and evaluated as a replacement for infectious canine hepatitis (canine adenovirus type 1; CAV-1) vaccines. In a genetic stability test, the vaccine strain remained nonpathogenic through five back passages in dogs and when given by the intranasal route.
E P, Bass, M A, Gill, W H, Beckenhauer
openaire   +2 more sources

Two genomic variations in the E1 region of canine adenovirus type 2 strains

Veterinary Microbiology, 1994
We amplified the E1 region of canine adenovirus type 2 genomes by the polymerase chain reaction (PCR) and analyzed the PCR products by using eight restriction endonucleases. Restriction patterns of the E1 region cleaved with HaeIII and RsaI revealed two genomic variations among the canine adenovirus type 2 strains. Although the clinical significance of
Yukinobu Tohya, Y Kataoka
exaly   +3 more sources

Canine adenovirus type 2 infection in four puppies with neurological signs

Veterinary Record, 2006
Four nine‐ to 11‐week‐old puppies developed respiratory and neurological signs due to an infection with canine adenovirus type 2 ( CAV‐2 ); three of these were euthanased. They had moderate, diffuse pneumonia but there were no histological abnormalities in the central nervous system ...
V, Benetka, H, Weissenböck, I, Kudielka, C, Pallan, G, Rothmüller, K, Möstl   +5 more
openaire   +2 more sources

Canine Adenovirus Type 2-Induced Immunity to Two Canine Adenoviruses in Pups with Maternal Antibody

American Journal of Veterinary Research, 1975
SUMMARY Twenty-four Beagle pups with high levels of maternal antibody to canine adenovirus type 1 (CAV-1) and canine adenovirus type 2 (CAV-2) were oronasally inoculated with CAV-2 at 4 weeks of age. The CAV-2 was isolated from pharyngeal swabs on postinoculation days 2 through 6. In spite of the infection, maternal antibody continued to decrease for 4
M, Appel, L E, Carmichael, D S, Robson
openaire   +2 more sources

In vitro functional genetic modification of canine adenovirus type 2 genome by CRISPR/Cas9

Laboratory Investigation, 2021
Genetically modified oncolytic adenoviruses have been proposed as a vehicle for cancer therapy. However, several concerns, such as toxicity to normal cells and organs, lack of suitable cell surface receptors to allow viral entry to the desired cell type(s), and activation of both innate and adaptive immune systems in patients, restrict the successful ...
Abdul Mohin Sajib, Payal Agarwal, Daniel J. Patton, Rebecca L. Nance, Natalie A. Stahr, Will P. Kretzschmar, Maninder Sandey, Bruce F. Smith   +7 more
openaire   +2 more sources

Identification and nucleotide sequence of the early region 1 from canine adenovirus types 1 and 2

Virus Research, 1989
The genome of canine adenovirus type 1 (CAV-1) has been cloned and restriction maps compiled. These maps are compared with those of canine adenovirus type 2 (CAV-2). The left ends of both genomes were further characterised by DNA sequence analysis. Several features of the DNA sequence and predicted polypeptide sequence are similar to those of the human
Heather M A Cavanagh
exaly   +3 more sources

SEROLOGICAL DETERMINATION OF CANINE ADENOVIRUS TYPE 2 (CAV-2) IN A CANINE SHELTER OF QUITO

2022
La traqueobronquitis infecciosa canina (TBIC) es una enfermedad frecuente y de alta morbilidad en lugares de hacinamiento como refugios o guarderías caninas. La aparición de brotes representa grandes dificultades tanto en la salud animal como el costo que genera el tratamiento de estos animales, por lo que es indispensable el diagnóstico oportuno para ...
Cepeda Ortiz, Grace Elizabeth, López Paredes, Nadia Valeria, Burgos Mayorga, Ana Rafaela   +2 more
openaire   +1 more source

Comparative pathogenicity of wild-type and E3-deleted canine adenovirus type 2 in experimental canine infections

Microbial Pathogenesis
Canine adenovirus type 2 (CAdV-2) is a major etiological agent of canine infectious respiratory disease (CIRD), responsible for acute laryngotracheitis and bronchopneumonia. In this study, we isolated and characterized three CAdV-2 strains from clinical cases in Guangxi, China.
Donglingzi Cao, Hui Zhang, Pingping Wang, Fanyuan Sun, Yefan Zhou, Luying Peng, Huabo Zhou, Yifeng Qin, Kang Ouyang, Yeshi Yin, Zuzhang Wei, Weijian Huang, Jianming Long, Ying Chen   +13 more
openaire   +2 more sources

Development of recombinant canine adenovirus type-2 expressing the Gn glycoprotein of Seoul virus

Biologicals, 2008
Seoul virus glycoprotein Gn is a major structural protein and candidate antigen of hantavirus that induces a highly immunogenic response for hantavirus vaccine. In this study, a replication-competent recombinant canine adenovirus type-2 expressing Gn was constructed by the in vitro ligation method.
Ziguo, Yuan, Xiuxiang, Zhang, Shoufeng, Zhang, Ye, Liu, Shengyan, Gao, Fei, Zhang, Huijuan, Xu, Xiaohu, Wang, Rongliang, Hu   +8 more
openaire   +2 more sources