Results 61 to 70 of about 29,388,619 (175)
Abstract An 8‐year‐old, entire, male German shorthaired pointer presented with acute respiratory distress, pyrexia and coughing following a period of boarding. Thoracic radiographs identified a caudal mediastinal mass effect with severe multilobar bronchopneumonia.
Yi Gu +4 more
wiley +1 more source
Transductional retargeting of human adenovirus type 5 to ανβ6 integrin for cancer gene therapy [PDF]
PhDA key impediment to successful cancer therapy with adenoviral vectors is the inefficient transduction of malignant tissue in vivo. Compounding this problem is the lack of cancer-specific targets, coupled with a shortage of corresponding high ...
Coughlan, Lynda
core +4 more sources
Bovine babesiosis is an important disease of cattle where Rhipicephalus microplus acts as a vector for the two causal organisms Babesia bovis and Babesia bigemina.
Ana Paula Silva +4 more
doaj +1 more source
In this study, internal organs (tongue, intestine, and spleen) of 23 free-ranging Italian wolves (Canis lupus italicus) found dead between 2017 and 2019 were tested for Carnivore protoparvovirus 1, Canine adenovirus (CAdV), and Canine circovirus ...
Andrea Balboni +9 more
doaj +1 more source
Identification of genes differentially expressed as result of adenovirus type 5- and adenovirus type 12-transformation [PDF]
Background: Cells transformed by human adenoviruses (Ad) exhibit differential capacities to induce tumours in immunocompetent rodents; for example, Ad12-transformed rodent cells are oncogenic whereas Ad5-transformed cells are not. The E1A gene determines
Strath, Janet +15 more
core +1 more source
Techniques that allow the manipulation of specific neural circuits have greatly increased in the past few years. DREADDs (Designer receptors exclusively activated by designer drugs) provide an elegant way to manipulate individual brain structures and/or ...
Juan-Carlos Cerpa +10 more
doaj +1 more source
Deep Mutational Scanning for the Study and Engineering of Protein Assemblies
This review explores how deep mutational scanning (DMS) can be used to improve understanding and accelerate engineering of protein assemblies, from natural fibers to engineered nanocages. We discuss various types of protein assemblies and their characterization, provide an introduction to the DMS technique, and then highlight examples in which DMS has ...
Jenna B. Wolfanger +2 more
wiley +1 more source
Clinical outcome, imaging and histopathological findings of liver cirrhosis in dogs
Abstract Cirrhosis is a severe and irreversible condition resulting from chronic liver injury, characterised by extensive fibrosis and regenerative nodules. This report describes three dogs with cirrhosis. The main clinical findings included ascites, reduced body condition score and inappetence. Anaemia, thrombocytopenia, hypoalbuminaemia, and elevated
Wanderson Feliciano Duarte da Silva +4 more
wiley +1 more source
Chicken adenovirus (CELO virus) particles augment receptor-mediated DNA delivery to mammalian cells and yield exceptional levels of stable transformants. [PDF]
Delivery of genes via receptor-mediated endocytosis is severely limited by the poor exit of endocytosed DNA from the endosome. A large enhancement in delivery efficiency has been obtained by including human adenovirus particles in the delivery system ...
Malt Cotlen +12 more
core
The coxsackievirus and adenovirus receptor (CAR) is a single-pass transmembrane cell adhesion molecule (CAM). CAR is expressed in numerous mammalian tissues including the brain, heart, lung, and testes.
Amani Wehbi +2 more
doaj +1 more source

