Results 51 to 60 of about 148 (128)

Canine adenovirus serotype 2 isolation and determination of its cultivation parameters

Ветеринария сегодня
Adenovirus infection in dogs caused by canine adenovirus serotype 2 predominantly results in respiratory disease typically manifested by respiratory tract lesions. Infectious laryngotracheitis is the most often recorded in dogs in the central part of the
A. A. Klimova
doaj   +1 more source

Feasibility of Canine Adenovirus Type 2 (CAV2) Based Vector for the Locus Coeruleus Optogenetic Activation in Non-Transgenic Rats: Implications for Functional Studies

Brain Sciences, 2022
The locus coeruleus norepinephrine (LC-NE) system modulates many visceral and cognitive functions, while LC-NE dysfunction leads to neurological and neurodegenerative conditions such as sleep disorders, depression, ADHD, or Alzheimer’s disease ...
Anna Kabanova, Elena Cavani, Nikos K. Logothetis, Oxana Eschenko   +3 more
doaj   +1 more source

Safeguarding a Flagship Species: Integrated Surveillance of Cross‐Species Pathogen Transmission in Giant Panda Ecosystems

Ecology and Evolution, Volume 16, Issue 3, March 2026.
Emerging infectious diseases increasingly threaten giant pandas and cohabiting species. This review analyzes pathogen transmission risks from domestic animals, wildlife, and vectors and proposes an integrated genomic surveillance framework for early warning and biodiversity conservation.
Xiaoli Sun, Yi Peng, Xiaoye Hao, Rong Dong, Zhilin Wang, Le Wang, Chengdong Wang, Xiangdong Wu, Zheng Chen, Wenbo Zhang, Xiaoli Tang   +10 more
wiley   +1 more source

Functional organization of the major late transcriptional unit of canine adenovirus type 2

Journal of General Virology, 2009
Vectors derived from canine adenovirus type 2 (CAV-2) are attractive candidates for gene therapy and live recombinant vaccines. CAV-2 vectors described thus far have been generated by modifying the virus genome, most notably early regions 1 and 3 or the fiber gene.
Szelechowski, Marion, Fournier, Annie, Richardson, Jennifer, Eloit, Marc, Klonjkowski, Bernard   +4 more
openaire   +4 more sources

Non‐Canonical Subiculum Circuit Organization and Function

Hippocampus, Volume 36, Issue 2, March 2026.
ABSTRACT The subiculum is highly interconnected with the hippocampus, sub‐regions of the thalamus, and the entorhinal and retrosplenial cortices. Together, these regions form a distributed network that plays critical roles in spatial cognition and learning and memory.
Pan Gao, Wenhao Cao, Douglas A. Nitz, Xiangmin Xu   +3 more
wiley   +1 more source

Molecular detection of pathogens in an equine fever diagnostic panel: 2019–2023

Equine Veterinary Journal, Volume 58, Issue 2, Page 486-496, March 2026.
Abstract Background A common diagnostic approach for febrile horses is to test for a panel of potential pathogens. Panels are curated by expert opinion and vary between diagnostic laboratories. Objectives To report the results of a newly developed equine fever diagnostic panel (EFDP) between 2019 and 2023 and evaluate the frequency of positive results.
Toby L. Pinn‐Woodcock, Melissa S. Aprea, Manigandan Lejeune, Joy E. Tomlinson   +3 more
wiley   +1 more source

A novel recombinant Peste des petits ruminants-canine adenovirus vaccine elicits long-lasting neutralizing antibody response against PPR in goats. [PDF]

PLoS ONE, 2012
BACKGROUND: Peste des petits ruminants (PPR) is a highly contagious infectious disease of goats, sheep and small wild ruminant species with high morbidity and mortality rates.
Junling Qin, Hainan Huang, Yang Ruan, Xiaoqiang Hou, Songtao Yang, Chengyu Wang, Geng Huang, Tiecheng Wang, Na Feng, Yuwei Gao, Xianzhu Xia   +10 more
doaj   +1 more source

Gene therapy for epilepsy: An emerging, promising approach for a serious neurological disorder

Journal of Internal Medicine, Volume 299, Issue 3, Page 302-327, March 2026.
Abstract Gene therapy is emerging as a groundbreaking strategy for treating epilepsy, offering new hope to patients who do not respond to conventional medications. Despite advancements in anti‐seizure treatments, nearly 30%–40% of individuals with epilepsy continue to experience uncontrolled seizures, highlighting the urgent need for more effective and
Marco Ledri, Merab Kokaia
wiley   +1 more source

Development of indirect ELISA for the detection of canine adenovirus type 2 antibodies in dog sera

Journal of Veterinary Science, 2020
Canine adenovirus type 2 (CAV-2) induces infectious laryngotracheitis in members of the family Canidae, including dogs. To date, no ELISA kits specific for CAV-2 antibody have been commercialized for dogs in Korea.We aimed to develop new indirect enzyme-linked immunosorbent assay (I-ELISA) to perform rapid, accurate serological surveys of CAV-2 in dog ...
Dong-Kun Yang, Ha-Hyun Kim, Siu Lee, Dongryul Oh, Jae Young Yoo, Bang-Hun Hyun   +5 more
openaire   +2 more sources

CAV-2-Mediated GFP and LRRK2G2019S Expression in the Macaca fascicularis Brain

Frontiers in Molecular Neuroscience, 2020
Parkinson’s disease is characterized by motor and nonmotor symptoms that gradually appear as a consequence of the selective loss of dopaminergic neurons in the substantia nigra pars compacta.
Carla di Caudo, Carla di Caudo, Ivan Martínez-Valbuena, Ivan Martínez-Valbuena, Ivan Martínez-Valbuena, Iñaki-Carril Mundiñano, Aurelie Gennetier, Maria Hernandez, Maria Hernandez, Mar Carmona-Abellan, Mar Carmona-Abellan, Irene Marcilla Garcia, Eric J. Kremer, Rosario Luquin, Rosario Luquin, Rosario Luquin   +15 more
doaj   +1 more source