Results 31 to 40 of about 29,388,619 (175)

Assessment and development of adenovirus type 11 for cancer therapy [PDF]

, 2010
PhDThe efficacy of oncolytic virotherapy is influenced by the interactions between the tumour, virus and host immunity. The first generation of oncolytic adenoviruses, based on serotype 5 (Ad5), has achieved limited success in clinical trials.
Wong, Han Hsi
core   +4 more sources

Bioprocess development for canine adenovirus type 2 vectors [PDF]

Gene Therapy, 2012
Canine adenovirus type 2 (CAV-2) vectors overcome many of the clinical immunogenic concerns related to vectors derived from human adenoviruses (AdVs). In addition, CAV-2 vectors preferentially transduce neurons with an efficient traffic via axons to afferent regions when injected into the brain.
Fernandes, P., Peixoto, C., Santiago, V. M., Kremer, E. J., Coroadinha, A. S., Alves, P. M.   +5 more
openaire   +3 more sources

Comparison of the diagnostic methods on the canine adenovirus type 2 infection [PDF]

Basic and Applied Pathology, 2010
ABSTRACT Background and aims: Canine adenovirus type 2 (CAV‐2) infection is typically diagnosed histopathologically since intranuclear inclusion bodies (IN/IBs) are demonstrable in the infected lung. However, it is sometimes difficult to identify IN/IBs, particularly in autolyzed tissues or samples from both early and late stages of infection, and ...
Soon-Seek, Yoon, Jae-Won, Byun, Young-Il, Park, Min-Jeong, Kim, You-Chan, Bae, Jae-Young, Song   +5 more
openaire   +2 more sources

Predominance of Canine Parainfluenza Virus and Mycoplasma in Canine Infectious Respiratory Disease Complex in Dogs

Pathogens, 2023
Canine infectious respiratory disease complex (CIRDC) is caused by different viruses and bacteria. Viruses associated with CIRDC include canine adenovirus type 2 (CAV-2), canine distemper virus (CDV), canine influenza virus (CIV), canine herpesvirus type
Aurelle Yondo, Allen A. Kalantari, Ingrid Fernandez-Marrero, Amy McKinney, Hemant K. Naikare, Binu T. Velayudhan   +5 more
doaj   +1 more source

Evaluation of tumor immunity after administration of conditionally replicative adenoviral vector in canine osteosarcoma patients

Heliyon, 2021
Osteosarcoma is one among the most common neoplasms in dogs. Current treatments show limited efficacy and fail to prevent metastasis. Conditionally replicative adenoviruses (CRAd) replicate exclusively in targeted tumor cells and release new virus ...
Payal Agarwal, Elizabeth A. Gammon, Maninder Sandey, Stephanie S. Lindley, Jey W. Koehler, Brad M. Matz, Annette N. Smith, Elena A. Kashentseva, Igor P. Dmitriev, David T. Curiel, Bruce F. Smith   +10 more
doaj   +1 more source

Proteomic Remodeling in the Failing Left Ventricle Adapting to Dyssynchrony. [PDF]

Proteomics Clin Appl
ABSTRACT Purpose In heart failure, dyssynchrony is associated with accelerated cardiac remodeling and a worse prognosis. Both restored with resynchronization. We have previously developed a mouse model of dyssynchrony and resynchronization and here assess changes in protein expression within that model.
Ljung K, Muntu NA, Reistam U, Kirk JA, Ståhlberg M.   +4 more
europepmc   +2 more sources

A Case of Sepsis Caused by ST80 Multidrug-Resistant Enterococcus faecium With Concurrent Klebsiella pneumoniae Infection in a Dog. [PDF]

Vet Med Sci
An 8‐year‐old dog developed acute respiratory distress that progressed to sepsis and death. Multidrug‐resistant Enterococcus faecium ST80 was isolated from the liver and kidney, while Klebsiella pneumoniae was detected in the lung by PCR. Whole‐genome sequencing showed that the ST80 isolates were genetically identical, suggesting hematogenous spread ...
Seo HM, La TM, Seo YR, Lee DY, Han HJ, Hyeon JY.   +5 more
europepmc   +2 more sources

Brain tumors induced in rats by human adenovirus type 12 [PDF]

, 1974
Oncogenesis of human adenovirus type 12 in the brain of rats was examined. Newborn rats of Sprague-Dawley and Donryu　strains were injected intracranially with human adenovirus type 12.　The incidence of intracranial tumors was 91% (30/33) in
Ogawa, Katsuo, Ohmori, Hiroyuki, Sonobe, Hiroshi, Murao, Tsuyoshi, Tsutsumi, Akira, Matsuo, Keisuke   +5 more
core   +1 more source

Adenovirus and its interaction with host cell proteins [PDF]

, 2007
The E1B55k gene in adenovirus type 5 was studied by generating recombinant viruses in which the E1B55k gene was N-terminally tagged with either a cyan fluorescent protein (CFP) tag or a tandem affinity purification (TAP) tag.
Carr, Sharon
core   +2 more sources

Transforming Genes of Canine Adenovirus Type 2

Journal of General Virology, 1988
Genes of canine adenovirus type 2 (CAd2) involved in transformation were localized and their functions investigated. Cells transformed by CAd2 whole DNA or the BamHI A fragment (leftmost 47%) totally lacked contact inhibition and were serum-independent, anchorage-independent and tumorigenic in newborn rats. All the cells transformed by the XbaI D (0 to
T, Tsukiyama, R, Shibata, Y, Katayama, M, Shinagawa   +3 more
openaire   +2 more sources