Immunogenicity of a novel inactivated canine adenovirus type 2 variant vaccine for dogs. [PDF]
The immunogenicity of vaccines containing the canine adenovirus (CAdV) type 2 (CAdV-2) variant has not yet been reported. We prepared a novel inactivated CAdV-2 variant vaccine using the CAV2232-41 strain, and evaluated its safety and immunogenicity in raccoon dogs.The growth kinetics of CAV2232-41 were determined using Madin-Darby Canine Kidney (MDCK)
Yang DK +6 more
europepmc +3 more sources
Preclinical Safety Evaluation of a Replication-Defective Canine Adenovirus Type 2 Vector-Based SARS-CoV-2 Vaccine Candidate in Murine Models [PDF]
Background: Adenoviral vectors are widely used in vaccine development; however, pre-existing immunity to common human adenovirus serotypes can limit their effectiveness.
Denis Omara +19 more
doaj +2 more sources
Molecular detection of canine viral infectious diseases in China: an investigation from 2018 to 2024 [PDF]
To analyze the prevalence of canine viral diseases in China, including canine parvovirus type 2 (CPV-2), canine coronavirus (CCoV), canine distemper virus (CDV), canine herpesvirus type 1 (CHV-1), canine parainfluenza virus (CPIV), canine influenza virus
Caihong Liu +17 more
doaj +2 more sources
Canine Adenovirus 2: A Natural Choice for Brain Circuit Dissection
Canine adenovirus-2 (CAV) is a canine pathogen that has been used in a variety of applications, from vaccines against more infectious strains of CAV to treatments for neurological disorders.
Andréanne Lavoie +3 more
exaly +3 more sources
IFNL3 reduces replication of CIRDC-associated viruses in canine airway epithelial cells [PDF]
Canine infectious respiratory disease complex (CIRDC) causes contagious respiratory disease in dogs and encompasses several etiologic agents. Viral pathogens associated with CIRDC include canine adenovirus type 2 (CAV-2), canine distemper virus (CDV ...
Swati Sharma +4 more
doaj +2 more sources
Molecular Epidemiology of Highly Diffusive DNA Viruses in Dogs and Cats from Romania [PDF]
Protoparvovirus carnivoran 1 (PPVC-1), Canine adenovirus type 1 and 2 (CAdV-1 and CAdV-2), and Canine circovirus (CanineCV) are highly diffusive viruses that affect domestic and wild carnivores worldwide, yet limited data are available on their ...
Andrea Balboni +9 more
doaj +2 more sources
Many clinically relevant tissues are refractory to Ad5 transduction because of negligible levels of the primary Ad5 receptor, the coxsackie and adenovirus receptor (CAR). Thus, development of Ad vectors that display CAR-independent tropism could lead directly to therapeutic gain.
Glasgow, Joel N +5 more
openaire +3 more sources
Canine circovirus and Canine adenovirus type 1 and 2 in dogs with parvoviral enteritis [PDF]
Canine parvovirus type 2 (CPV-2) is one of the most relevant pathogens associated with enteritis in dogs and is frequently reported in association with the detection of other pathogens in faeces. In this study the concomitant presence of Canine circovirus (CanineCV) and Canine adenovirus (CAdV) DNA in faecal or intestine samples of 95 dogs with ...
Balboni A +6 more
openaire +3 more sources
Canine adenovirus type 2 (CAdV-2) is often found in co-infections with other pathogens causing canine infectious respiratory disease (CIRD). Rapid, efficient, and convenient pathogen detection is the best approach for early confirmatory diagnosis.
Li Xiao +7 more
doaj +1 more source
First Detection, Molecular Characterization, and Phylogenetic Analysis of Canine Influenza Virus A (H3N2) in Pakistan. [PDF]
Influenza and Other Respiratory Viruses, Volume 20, Issue 9, September 2026.
Umar S, Manzoor A.
europepmc +2 more sources

