Results 11 to 20 of about 3,629 (180)

Neurobehavioral Comorbidities in Canine Idiopathic Epilepsy: New Insights into Cognitive and Emotional Domains [PDF]

Animals
Neurobehavioral comorbidities in dogs with idiopathic epilepsy (IE) are increasingly recognized, yet their phenotypic variability and clinical implications remain poorly understood.
Rosado Belén, Palacio Jorge, Menchaca Carolina, García-Belenguer Sylvia   +3 more
doaj   +5 more sources

Retrospective study on canine idiopathic epilepsy treatment in primary care practices in the United States [PDF]

Frontiers in Veterinary Science
The aim of this study is twofold: to characterize the epidemiology of idiopathic epilepsy (IE) in a large US primary care provider, and to investigate primary care veterinarians’ anti-seizure drugs (ASDs) prescribing practices.
Elisa Pompermaier, Jo Ann Morrison, Fabio Stabile, Luisa De Risio   +3 more
doaj   +4 more sources

Imepitoin as novel treatment option for canine idiopathic epilepsy: pharmacokinetics, distribution, and metabolism in dogs [PDF]

Journal of Veterinary Pharmacology and Therapeutics, 2014
Imepitoin is a novel anti‐epileptic licensed in the European Union for the treatment of canine idiopathic epilepsy. The aim of this study was to characterize the pharmacokinetics of imepitoin in dogs and to evaluate the interaction with drug metabolizing enzymes. Upon administration of imepitoin tablets at a dose of 30 mg/kg to beagle dogs, high plasma
Rundfeldt C, Gasparic A, Wlaź P.
exaly   +5 more sources

Behavioral Changes in Dogs With Idiopathic Epilepsy Compared to Other Medical Populations

Frontiers in Veterinary Science, 2019
Anxiety related behaviors have been reported in humans diagnosed with idiopathic epilepsy (IE) and such traits may be altered depending on seizure phase. The purpose of this study was to determine the presence and severity of anxiety related behaviors in
Hilary A Levitin, Devon W Hague, Kelly C Ballantyne   +2 more
exaly   +3 more sources

The effect of phenobarbital treatment on behavioral comorbidities and on the composition and function of the fecal microbiome in dogs with idiopathic epilepsy

Frontiers in Veterinary Science, 2022
Phenobarbital (PB) is one of the most important antiseizure drugs (ASDs) to treat canine idiopathic epilepsy (IE). The effect of PB on the taxonomic changes in gastrointestinal microbiota (GIM) and their functions is less known, which may explain parts ...
Antja Watanangura, Sebastian Meller, Jan S Suchodolski   +2 more
exaly   +3 more sources

A comparative analysis and critical review of two rTMS treatment durations in dogs with drug-resistant idiopathic epilepsy [PDF]

BMC Veterinary Research
Background Repetitive transcranial magnetic stimulation (rTMS) is an effective, non-invasive management option for canine drug-resistant idiopathic epilepsy, but optimal stimulation protocols have not yet been established.
Delia Hünting, Sebastian Meller, Friederike Twele, Nina Meyerhoff, Sofie F.M. Bhatti, Holger A. Volk, Marios Charalambous   +6 more
doaj   +2 more sources

The fecal metabolome and microbiome are altered in dogs with idiopathic epilepsy compared to healthy dogs [PDF]

Scientific Reports
Idiopathic epilepsy (IE) is the most common chronic neurological disease in dogs, and a natural animal model for human epilepsy types with genetic and unknown etiology. The microbiota-gut-brain axis (MGBA) is a promising target for improving brain health
Fien Verdoodt, Myriam Hesta, Evy Goossens, Filip Van Immerseel, Jenifer Molina, Luc Van Ham, Lynn Vanhaecke, Lieselot Y. Hemeryck, Sofie F.M. Bhatti   +8 more
doaj   +2 more sources

ADAM23 is a common risk gene for canine idiopathic epilepsy. [PDF]

BMC Genet, 2017
Idiopathic or genetic adult-onset epilepsy is a common neurological disorder in domestic dogs. Genetic association has been reported only with ADAM23 on CFA 37 in few breeds. To identify novel epilepsy genes, we performed genome-wide association (GWA) analyses in four new breeds, and investigated the association of the previously reported ADAM23 ...
Koskinen LL, Seppälä EH, Weissl J, Jokinen TS, Viitmaa R, Hänninen RL, Quignon P, Fischer A, André C, Lohi H.   +9 more
europepmc   +7 more sources

Scalp electrode placement accuracy for the canine electroencephalography array [PDF]

Frontiers in Veterinary Science
IntroductionDespite the common occurrence of idiopathic epilepsy amongst neurological conditions in dogs, electroencephalography (EEG), the gold standard for seizure detection, is relatively neglected. The use of EEG in veterinary medicine is rudimentary
Stephen Everest, Stephen Everest, Myles St-Denis, Robert Dony, Luis Gaitero, Alexander Zur Linden, Miguel A. Cortez, Thomas Parmentier, Fiona M. K. James   +8 more
doaj   +2 more sources

The Postictal Phase in Canine Idiopathic Epilepsy: Semiology, Management, and Impact on the Quality of Life from the Owners' Perspective. [PDF]

Animals (Basel), 2023
Background: Dogs with idiopathic epilepsy experience not only the preictal and ictal seizure phases but also the postictal phase. To date, research has primarily focused on the preictal and ictal semiology and therapeutic control of ictal events. Research into the postictal phase‘s pathophysiology, as a therapeutic target and how it impacts the quality
Kähn C, Meyerhoff N, Meller S, Nessler JN, Volk HA, Charalambous M.   +5 more
europepmc   +4 more sources