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As Guest Editors of this Special Issue on canine mammary tumors, we are pleased to present a collection of articles on this highly relevant and timely topic [...
Luiz Gustavo de Almeida Chuffa +7 more
core +1 more source
DNA Methylation Status of the Estrogen Receptor α Gene in Canine Mammary Tumors
Estrogen receptor α (ERα) has an important role in mammary carcinogenesis, prognosis, and treatment. In human and canine mammary cancer, the most aggressive tumors show loss of ERα expression, which in human breast cancer has been attributed to ...
Yara de Oliveira Brandão +6 more
core +1 more source
Evaluation of 14-3-3σ as a Prognostic Marker in Canine Mammary Tumors
14-3-3σ is a regulatory protein involved in cell cycle control and has been implicated in both tumor-suppressive and tumor-promoting roles, depending on the biological context. While extensively studied in human cancers, limited information is available
Ana Hiruta +4 more
doaj +1 more source
Establishment of a PCR analysis method for canine BRCA2
Background Mammary tumors are the most common tumor type in both human and canine females. In women, carriers of mutations in BRCA2, a tumor suppressor gene product, have a higher risk of breast cancer.
Yoshikawa Yasunaga +10 more
doaj +1 more source
Evaluation of MCL-1 as a prognostic factor in canine mammary gland tumors.
Myeloid cell leukemia-1 (MCL-1), which belongs to the anti-apoptotic B cell lymphoma-2 family protein, is overexpressed in various cancers and is associated with cell immortality, malignant transformation, chemoresistance, and poor prognosis in humans ...
Jaeho Cho +3 more
doaj +1 more source
First description of basaloid carcinoma of the canine mammary gland: case report
The objective of this case report was to describe histopathological and immunohistochemical characteristics of the first reported basaloid carcinomas in the canine mammary gland.
K.Y.R. Nakagaki +3 more
doaj +1 more source
Antioxidant enzymes in canine mammary tumors
Spontaneous mammary tumors are very common in bitches. The involvement of oxidative stress and the function of antioxidant enzymes in cancerogenesis have been studied in depth in human medicine, while data in veterinary medicine are still fragmentary ...
FERLIZZA, ENEA +7 more
core +1 more source
Canine Mammary Tumors as a Potential Model for Human Breast Cancer in Comparative Oncology
Clinical and molecular similarities between canine mammary tumors (CMTs) and human breast cancer (HBC) propel scientists to further study their application in comparative oncology as a model for human breast cancer.
Amirhossein Razavirad +3 more
doaj +1 more source
EGFR and HER-2 expression by immunohistochemistry (IHC) and their mRNA by in situ hybridization (ISH) in canine mammary carcinomas in mixed tumors and carcinosarcomas.
Karine Araújo Damasceno (3142944) +8 more
core +1 more source
Comparative expression pathway analysis of human and canine mammary tumors [PDF]
Background Spontaneous tumors in dog have been demonstrated to share many features with their human counterparts, including relevant molecular targets, histological appearance, genetics, biological behavior and response to conventional treatments ...
John Castle +64 more
core +1 more source

