Veterinary Sciences, 2022 Canine mammary tumor (CMT) is the most common tumor in canines after skin tumors. Long noncoding RNAs (lncRNAs) have crucial roles in human breast tumor initiation and progression, but the role of lncRNAs in canine mammary tumors is unclear.
Baochun Lu +4 more
doaj +2 more sources
Ligand-independent canonical Wnt activity in canine mammary tumor cell lines associated with aberrant LEF1 expression. [PDF]
PLoS ONE, 2014 Pet dogs very frequently develop spontaneous mammary tumors and have been suggested as a good model organism for breast cancer research. In order to obtain an insight into underlying signaling mechanisms during canine mammary tumorigenesis, in this study
Ana Gracanin +7 more
doaj +3 more sources
Presence and importance of oxidative stress parameters in malignant mammary gland tumors in dogs [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2021 This study aimed to evaluate the presence of oxidative stress based on lipid peroxidation and the DNA damage markers malondialdehyde (MDA) and 8-hydroxy-2"-deoxyguanosine (8-OHdG) in canine mammary gland carcinomas using immunohistochemistry techniques ...
Emin KARAKURT +6 more
doaj +1 more source
Celastrol Inhibits Canine Mammary Tumor Cells by Inducing Apoptosis via the Caspase Pathway
Frontiers in Veterinary Science, 2022 Canine mammary tumor is a serious disease threatening the health of dogs and can be used as a research model for human breast cancer. The study of canine mammary tumor has a role in improving the welfare of dogs.
Guoxing Ou +5 more
doaj +1 more source
Evaluation of Cytokeratin 7 Expression in Different Mammary Gland Neoplasms [PDF]
Iranian Journal of Veterinary Medicine, 2021 BACKGROUND: Cytokeratins are non-contractile intermediate filaments engaged in anchoring and structural functions forming a network to support cytoplasm.
Elnaz Elahirad +4 more
doaj +1 more source
Down-expression of klotho in canine mammary gland tumors and its prognostic significance
PLoS ONE, 2022 Since the discovery of klotho as an anti-aging gene, its association with tumors has been studied. Several previous studies have reported the down-expression of klotho in various human cancers, and much of its mechanism has been revealed.
Heaji Chung +3 more
doaj +2 more sources
Frontiers in Veterinary Science, 2021 Mammary tumors are the most prevalent neoplasms in non-neutered female dogs, with genetic and epigenetic alterations contributing to canine mammary carcinogenesis.
Luiz Roberto Biondi +4 more
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Expression of tumour transcription factor GLI1 in canine mammary tumours tissue
Veterinary Medicine and Science, 2022 Background Mammary tumor is one of the most common diseases of canine in pet clinics. Objectives This study investigates the distribution and expression of the tumor transcription factor GLI1 and the downstream proteins, Bmi1 and Sox2, in canine mammary ...
Penggang Liu +5 more
doaj +1 more source
Epidemiological Investigation of Canine Mammary Tumors in Mainland China Between 2017 and 2021
Frontiers in Veterinary Science, 2022 Epidemiological studies enable us to analyze disease behavior, define risk factors, and establish fundamental prognostic criteria. This study aimed to determine the epidemiological and clinical characteristics of canine tumors diagnosed during the years ...
Hui-Hua Zheng +6 more
doaj +1 more source
Anti-influenza neuraminidase inhibitor oseltamivir phosphate induces canine mammary cancer cell aggressiveness. [PDF]
PLoS ONE, 2015 Oseltamivir phosphate is a widely used anti-influenza sialidase inhibitor. Sialylation, governed by sialyltransferases and sialidases, is strongly implicated in the oncogenesis and progression of breast cancer.
Joana T de Oliveira +10 more
doaj +1 more source